Synthesis of fluorosugar analogues of 2,5,6-trichloro-1-(β-D- ribofuranosyl)benzimidazole as antivirals with potentially increased glycosidic bond stability

Journal of Medicinal Chemistry

Volumn 43, Issue 12, 2000, Pages 2473-2478

  Gudmundsson, Kristjan S ^a,b   Freeman, George A ^a,b   Drach, John C ^b   Townsend, Leroy B ^b  

^a GLAXOSMITHKLINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,5,6 TRICHLORO 1 (BETA DEXTRO RIBOFURANOSYL)BENZIMIDAZOLE; BENZIMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CYTOMEGALOVIRUS; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; GLYCOSYLATION;

ANTIVIRAL AGENTS; BENZIMIDAZOLES; CELL DIVISION; CELLS, CULTURED; CYTOMEGALOVIRUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; FLUORINE; HERPESVIRUS 1, HUMAN; HUMANS; PLAQUE ASSAY; RIBONUCLEOSIDES; SKIN; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0033934529     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990219s     Document Type: Article

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