Effects of aniracetam on impaired sleep patterns in stroke-prone spontaneously hypertensive rats

Psychiatry and Clinical Neurosciences

Volumn 54, Issue 3, 2000, Pages 314-316

  Kimura, Mayumi ^a   Okano, Shukan ^a   Inoué, Shojiro ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Acetylcholine deficit; Aniracetam; Infarction; Rapid eye movement sleep impairment; Spontaneously hypertensive rat

Indexed keywords

ANIRACETAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; COGNITION; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; ESSENTIAL HYPERTENSION; MULTIINFARCT DEMENTIA; NONHUMAN; RAT; REM SLEEP; SLEEP PATTERN; STROKE;

ANIMALS; MALE; NOOTROPIC AGENTS; POLYSOMNOGRAPHY; PYRROLIDINONES; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SLEEP STAGES; SLEEP, REM;

EID: 0033934521     PISSN: 13231316     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1819.2000.00693.x     Document Type: Conference Paper

References (4)

1. Otomo E, Harai S, Terashi A et al. Clinical utility of aniracetam in treatment of neurological symptoms accompanying cerebrovascular disorders - a double-blinded comparative trial using a placebo as a control. J. Clin. Exp. Med. 1991; 156: 143-187.
2. Togashi H, Matsumoto M, Yoshioka M, Hirokami M, Minami M, Saito H. Neurochemical profiles in cerebrospinal fluid of stroke-prone spontaneously hypertensive rats. Neurosci. Lett. 1994; 27: 520-526.
3. Koyama Y, Kayama Y, Sakai K. Differential physiological properties of two populations of PS-on neurons in the mesopontine tegmentum. In: Mallick BN, Inoué S (eds). Rapid Eye Movement Sleep. Narosa Publishing House, New Delhi, 1999; 221-232.
4. Nakamura K, Shirane M. Activation of the reticulothalamic cholinergic pathway by the major metabolites of aniracetam. Eur. J. Pharmacol. 1999; 380: 81-39.