Activated macrophages increase the susceptibility of rat hepatocytes to ethanol-induced oxidative stress: Conflicting effects of nitric oxide

Alcohol and Alcoholism

Volumn 35, Issue 3, 2000, Pages 230-235

  Griffon, B ^a   Cillard, J ^a   Chevanne, M ^a   Morel, I ^a   Cillard, P ^a   Sergent, O ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ARTICLE; COCULTURE; CONTROLLED STUDY; ENZYME INDUCTION; INFLAMMATION; LIVER CELL; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0033933327     PISSN: 07350414     EISSN: None     Source Type: Journal    
DOI: 10.1093/alcalc/35.3.230     Document Type: Article

References (39)

1. Adachi, Y., Bradford, B. U., Gao, W., Bojes, H. K. and Thurman, R. G. (1994) Inactivation of Kupffer cells prevents early alcohol-induced liver injury. Hepatology 20, 453-460.
2. Adams, D. O., Kao, K.,Farb, R. and Pizzo, S. U. (1980) Effector mechanisms of cytolytically activated macrophages. Secretion of cytolytic factor by activated macrophages and its relation to secreted neutral protease. Journal of Immunology 124, 293-300.
3. Bautista, A. P. and Spitzer, J. J. (1992) Acute ethanol intoxication stimulates Superoxide anion production by in situ perfused rat liver. Hepatology 15, 892-898.
4. Billiar, T. R., Curran, R. D., Stuehr, D. J., West, M. A., Bentz, B. G. and Simmons, R. L. (1989) An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. Journal of Experimental Medicine 169, 1467-1472.
5. Bradford, M. M. (1976) A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Analytical Biochemistry 72, 248-254.
6. Chamulitrat, W. and Spitzer, J. J. (1996) Nitric oxide and liver injury in alcohol-fed rats after lipopolysaccharide administration. Alcoholism: Clinical and Experimental Research 20, 1065-1070.
7. Chamulitrat, W., Jordan, S. J. and Mason, R. D. (1994) Nitric oxide production during endotoxin shock in carbon tetrachloride-treated rats. Molecular Pharmacology 46, 391-397.
8. Curran, R. D., Billiar, T. R., Stuehr, D. J., Hoffmann, K. and Simmons, R. L. (1989) Hepatocyles produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells. Journal of Experimental Medicine 170, 1769-1774.
9. Gardner, C. R., Heck, D. E., Yang, C. S., Thomas, P. E., Zhang, X. J., DeGeorge, G. L., Laskin, J. D. and Laskin, D. L. (1998) Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat. Hepatology 26, 748-754.
10. Goto, M., Lemasters, J. J. and Thurman, R. G. (1994) Activation of voltage-dependent calcium channels in Kupffer cells by chronic treatment with alcohol in the rat. Journal of Pharmacology and Experimental Therapeutics 267, 1264-1268.
11. 2 release. Hepatology 28, 1300-1308.
12. Guguen, C., Guillouzo, A., Boisnard, M., Le Cam, A. and Bourel, M. (1975) Etude structurale de monocouches d'hépatocytes de rat adulte cultivés en présence d'hémisuccinate d'hydrocortisone. Biologie et Gastroenterologie 8, 223-231.
13. Hunt, N. and Goldin, R. (1992) Nitric oxide production by monocytes in alcoholic liver diseases. Journal of Hepatology 14, 146-150.
14. Ishii, K., Furudera, S., Kumashiro, R., Seo, J., Koga, Y, Sata, M. and Tanikawa, K. (1994) Role of serum interleukin-8 and intercellular adhesion molecule-1 in the severity of alcoholic hepatitis. Alcohol and Alcoholism 29 (Suppl.), 81-85.
15. Jaeschke, H., Farhood, A. and Smith, W. (1994) Contribution of complement-stimulated hepatic macrophages and neutrophils to endotoxin-induced liver injury in rats. Hepatology 19, 973-979.
16. Janero, D. R. (1990) Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radical Biology and Medicine 9, 515-540.
17. Karakucuk, I., Dilly, S. A. and Maxwell, J. D. (1989) Portal tract macrophages are increased in alcoholic liver disease. Histopathology 14, 245-254.
18. Kmiec, Z., Hughes, R. D., Moore, K. P., Sheron, N., Gove, C. D., Nouri-Aria, K. T. and Williams, R. (1993) Effect of supernatants from Kupffer cells stimulated with galactosamine and endotoxin on the function of isolated rat hepatocytes. Hepato-Gastroenterology 40, 259-261.
19. Koop, D. R., Klopfenstein, B., Limuro, Y. and Thurman, R. G. (1997) Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1. Molecular Pharmacology 51, 944-950.
20. Kuiper, J., Brouwer, A., Knook, D. L. and Van Berkel, T. J. C. (1994) Kupffer and sinusoidal endothelial cells. In The Liver: Biology and Pathobiology, 3rd edn, Arias, I. M., Boyer, J. L., Fausto, N., Jacoby, W. B., Schachler, D. A. and Shafritz, D. A. eds, pp. 791-818. Raven Press, New York.
21. Kurose, I., Kato, S., Fukumura, D., Miura, S., Suematsu, M. and Tsuchiya, M. (1993) Nitric oxide mediates lipopolysaccharide-induced alteration of mitochondrial function in cultured hepatocytes and isolated perfused liver. Hepatology 18, 380-388.
22. Laskin, D. L. and Pilaro, A. M. (1986) Potential role of activated macrophages in acetominophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver. Toxicology and Applied Pharmacology 86, 204-215.
23. Lee, H.-S. and Csallany, A. S. (1987) Measurement of free and bound malondialdehyde in vitamin E-deficient and -supplemented rat liver tissues. Lipids 22, 104-107.
24. Limuro, Y., Yamamoto, M., Kohno, H., Itakura, J., Fujii, H. and Matsumoto, Y. ( 1994) Blockade of liver macrophages by gadolinium chloride reduces lethality in endotoxemic rats - analysis of mechanisms of lethality in endotoxemia. Journal of Leukocyte Biology 55, 723-728.
25. Mawet, E., Shiratori, Y., Hikida, Y, Takada, H., Yoshida, H., Okano, K., Komatsu, Y, Matsumura, M., Niwa, Y. and Omata, M. (1996) Cytokine-induced neutrophil chemoattractant release from hepatocytes is modulated by Kupffer cells. Hepatology 23, 353-358.
26. McMillan, J. M. and Jollow, D. J. (1995) Macrophage enhancement of galactosamine hepatotoxicity using rat hepatocyte culture system. Research Communications in Chemical Pathology and Pharmacology 88, 327-338.
27. Morel, I., Lescoat, G., Cillard, J., Pasdeloup, N., Brissot, P. and Cillard, P. (1990) Quantitative evaluation of free malondialdehyde and enzyme leakage as indices of iron damage in rat hepatocyte cultures. Involvement of free radicals. Biochemical Pharmacology 39, 1647-1655.
28. Muller, A. and Sies, H. (1982) Role of alcohol dehydrogenase activity and of acetaldehyde in ethanol-induced ethane and pentane production by isolated perfused rat liver. Biochemical Journal 206, 153-156.
29. Nagase, S., Isobe, H., Ayukawa, K., Sakai, H. and Nawata, H. (1995) Inhibition of nitric oxide production increases dimethylnitrosamine-induced liver injury in rats. Journal of Hepatology 23, 601-604.
30. Sergent, O., Morel, I., Chevanne, M., Cillard, P. and Cillard, J. (1995) Oxidative stress induced by ethanol in rat hepatocyte cultures. Biochemistry and Molecular Biology International 35, 575-583.
31. Sergent, O., Griffon, B., Morel, I., Chevanne, M., Dubos, M. P., Cillard, P. and Cillard, J. (1997) Effect of nitric oxide on iron-mediated oxidative stress in primary rat hepatocyte culture. Hepatology 25, 122-127.
32. Stadler, J., Billiar, T. R., Curran, R. D., Stuehr, D. J., Ochoa, J. and Simmons, R. L. (1991) Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. American Journal of Physiology 260, C910-C916.
33. Suzuki, S., Nakamura, S., Serizawa, A., Sakaguchi, T., Konno, H., Muro, H., Kosugi, I. and Baba, S. (1996) Role of Kupffer cells and the spleen in modulation of endotoxin-induced liver injury after partial hepatectomy. Hepatology 24, 219-225.
34. Takahashi, T., Kamimura, T. and Ichida, F. (1987) Ultrastructural findings on polymorphonuclear leucocyte infiltration and acute hepatocellular damage in alcoholic hepatitis. Liver 7, 347-358.
35. Takeyamo, Y, Kamiruma, S., Kuroiwa, A., Sohda, T., Irie, M., Shijo, H. and Okumura, M. (1996) Role of Kupffer cell-derived reactive oxygen intermediates in alcoholic liver disease in rat in vivo. Alcoholism: Clinical and Experimental Research 20, 335A-339A.
36. Wang, J. F., Greenberg, S. S. and Spitzer, J. J. (1995) Chronic alcohol administration stimulates nitric oxide formation in the rat liver with or without pretreatment with lipopolysaccharide. Alcoholism: Clinical and Experimental Research 19, 387-393.
37. Wickramasinghe, S. N. (1989) Role of Superoxide anion radicals in ethanol metabolism by blood monocyte-derived human macrophages. Journal of Experimental Medicine 169, 755-763.
38. Williams, A. J. K. and Barry, R. E. (1987) Free radical generation by neutrophils: A potential mechanism of cellular injury in acute alcoholic hepatitis. Gut 28, 1157-1161.
39. Yamada, S., Mochida, S., Ohno, A., Hirata, K., Ogata, I., Ohta, Y. and Fujiwara, K. (1991) Evidence for enhanced secretory function of hepatic macrophages after long-term ethanol feeding in rats. Liver 11, 220-224.