Analysis of the mechanisms of expiratory asynchrony in pressure support ventilation: A mathematical approach

Journal of Applied Physiology

Volumn 88, Issue 6, 2000, Pages 2143-2150

  Yamada, Yoshitsugu ^a   Du, Hong Lin ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b Clinical Research Department   (United States)

Author keywords

Mathematical modeling; Mechanical ventilation; Patient ventilator synchrony

Indexed keywords

AIRFLOW; ARTICLE; ARTIFICIAL VENTILATION; BREATHING MECHANICS; LUNG VENTILATION; MATHEMATICAL MODEL; PRIORITY JOURNAL;

EID: 0033933102     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.2000.88.6.2143     Document Type: Article

References (21)

1. Aslanian P and Brochard LJ. Partial ventilatory support. In: Physiological Basis of Ventilatory Support, edited by Marini JJ and Slutsky AS. New York: Marcel Dekker, 1998, p. 817-846.
2. Behrakis PK, Higgs BD, Baydur A, Zin WA, and Milic-Emili J. Respiratory mechanics during halothane anesthesia and anesthesia-paralysis in humans. J Appl Physiol 55: 1085-1092, 1983.
3. Bonmarchand G, Chevron V, Menard J-F, Girault C, Morits-Berthelot F, and Pasquis P, and Leroy J. Effects of pressure ramp slope values on the work of breathing during pressure support ventilation in restrictive patients. Crit Care Med 27: 715-722, 1999.
4. Branson RD and Campbell RS. Pressure support ventilation, patient-ventilator synchrony, and ventilator algorithm. Respir Care 43: 1045-1047, 1998.
5. Branson RD and Chatburn RL. New generation of microprocessor-based ventilators. In: Principles and Practice of Mechanical Ventilation, edited by Tobin MJ. New York: McGraw-Hill, 1994, p. 1247-1256.
6. Bunburaphong T, Imanaka H, Nishimura M, Hess D, and Kacmarek RM. Performance characteristics of bilevel pressure ventilators: a lung model study. Chest 111: 1050-1060, 1997.
7. Chao DC, Scheinhorn DJ, and Stearn-Hassenpflug M. Patient-ventilator trigger asynchrony in prolonged mechanical ventilation. Chest 112:1592-1599, 1997.
8. Fabry B, Guttmann J, Eberhard L, Bauer T, Haberthur C, and Wolff G. An analysis of desynchronization between the spontaneous breathing and ventilator during inspiratory pressure support. Chest 107: 1387-1394, 1995.
9. Garcia-Raimundo M, Fraga R, Saz T, Aguilar G, Belda FJ, and Maruenda A. Incidence and types of desynchronization between spontaneous breaths and ventilator assistance with pressure support during routine weaning from mechanical ventilation in postoperative patients (Abstract). Crit Care Med 27: S335, 1999.
10. Jubran A, Van de Graaff WB, and Tobin MJ. Variability of patient-ventilator interaction with pressure support ventilation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 152: 129-136, 1995.
11. MacIntyre NR. Respiratory function during pressure support ventilation. Chest 89: 677-683, 1986.
12. MacIntyre NR. Weaning from mechanical ventilator support: volume assisting intermittent breaths vs. pressure assisting every breath. Respir Care 33: 121-125, 1988.
13. Milic-Emili J and Zin WA. Relationship between neuromuscular respiratory drive and ventilatory output. In: Handbook of Physiology. The Respiratory System. Bethesda, MD: Am. Physiol. Soc., 1986, sect. 3, vol. III, pt. 2, p. 631-646.
14. Nava S, Bruschi C, Fracchia C, Braschi A, and Rubini F. Patient-ventilator interaction and inspiratory effort during pressure support ventilation in patients with different pathologies. Eur Respir J 10: 177-183, 1997.
15. Nellcor Puritan Bennett. Nellcor Puritan Bennett 840 Ventilator Operating Manual (version A). St. Louis, MO: Mallinkrodt, 1997.
16. Van de Graaff WB, Gordey K, Dornseif SE, Dries DJ, Kleinman BS, Kumar P, and Mathru M. Pressure support: changes in ventilatory pattern and components of the work of breathing. Chest 100: 1082-1089, 1991.
17. Yamada Y and Du H-L. Effects of different pressure support termination on patient-ventilator synchrony. Respir Care 43: 1048-1057, 1998.
18. Yamada Y, Shigeta M, Suwa K, and Hanaoka K. Respiratory muscle pressure analysis in pressure-support ventilation. J Appl Physiol 77: 2237-2243, 1994.
19. Younes M. Proportional assist ventilation and pressure support ventilation: similarities and differences. In: Ventilatory Failure, edited by Marini JJ and Roussos C. Berlin: Springer, 1992, p. 361-380.
20. Younes M. Patient-ventilator interaction with pressure-assisted modalities of ventilatory support. Semin Respir Med 14: 299-322, 1993.
21. Zin WA, Pengelly LD, and Milic-Emili J. Single-breath method for measurement of respiratory mechanics in anesthetized animals. J Appl Physiol 52: 1266-1271, 1982.