Caries inhibitory activity of cacao bean husk extract in in-vitro and animal experiments

Archives of Oral Biology

Volumn 45, Issue 8, 2000, Pages 639-645

  Ooshima, T ^a   Osaka, Y ^a   Sasaki, H ^a   Osawa, K ^b   Yasuda, H ^b   Matsumura, M ^a   Sobue, S ^a   Matsumoto, M ^a  

^a OSAKA UNIVERSITY   (Japan)

^b Lotte Co Ltd   (Japan)

Author keywords

Cacao bean husk; Dental caries; Enzyme inhibitors; Glucosyltransferase; Mutans streptococci

Indexed keywords

ANTICARIES AGENT; BACTERIAL POLYSACCHARIDE; CACAO EXTRACT; GLUCAN; GLUCOSYLTRANSFERASE; PLANT EXTRACT; SUCROSE; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL GROWTH; BACTERIUM ADHERENCE; CACAO; CARIES PREVENTION; CELL ADHESION; CONCENTRATION RESPONSE; DENTAL CARIES; DRUG EFFECT; DRUG SYNTHESIS; ENZYMOLOGY; FACTORIAL ANALYSIS; GERMFREE ANIMAL; GROWTH INHIBITION; GROWTH, DEVELOPMENT AND AGING; MALE; METABOLISM; MICROBIOLOGY; NEWBORN; NONHUMAN; PLANT; RAT; RAT STRAIN; SOLUBILITY; STATISTICAL ANALYSIS; STREPTOCOCCUS MUTANS; STREPTOCOCCUS SOBRINUS; TOOTH PLAQUE; WATER SUPPLY;

ANALYSIS OF VARIANCE; ANIMALS; BACTERIAL ADHESION; CACAO; CARIOSTATIC AGENTS; DENTAL CARIES; DENTAL PLAQUE; FACTOR ANALYSIS, STATISTICAL; GLUCANS; GLUCOSYLTRANSFERASES; MALE; PHYTOTHERAPY; PLANT COMPONENTS; PLANT EXTRACTS; POLYSACCHARIDES, BACTERIAL; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SPECIFIC PATHOGEN-FREE ORGANISMS; STREPTOCOCCUS MUTANS; STREPTOCOCCUS SOBRINUS; SUCROSE; WATER SUPPLY;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA; PHASEOLUS (ANGIOSPERM); STREPTOCOCCUS MUTANS; STREPTOCOCCUS SOBRINUS; STREPTOCOCCUS SOBRINUS 6715; THEOBROMA CACAO;

EID: 0033932238     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9969(00)00042-X     Document Type: Article

References (19)

1. Hada S., Kakiuchi N., Hattori M., Namba T. Identification of antibacterial principles against Streptococcus mutans and inhibitory principles against glucosyltransferase from the seed of Areca catechu L. Phytother Research. 3:1989;140-144.
2. Hamada S., Horikoshi T., Minami T., Okahashi N., Koga T. Purification and characterization of cell-associated glucosyltransferase synthesizing water-insoluble glucan from serotype c Streptococcus mutans. Journal of General Microbiology. 135:1989;335-344.
3. Hamada S., Koga T., Ooshima T. Virulence factors of Streptococcus mutans and dental caries prevention. Journal of Dental Research. 63:1984;407-411.
4. Hamada S., Torii M. Effect of sucrose in culture media on the location of glucosyltransferase of Streptococcus mutans and cell adherence to glass surfaces. Infection and Immunity. 20:1978;592-599.
5. Hamada S., Torii M., Kotani S., Tsuchitani Y. Adherence of Streptococcus sanguis clinical isolates to smooth surfaces and interaction of the isolates with Streptococcus mutans glucosyltransferase. Infection and Immunity. 32:1981;364-372.
6. Keyes P.H. A method of recording and scoring gross carious lesions in the molar teeth of Syrian hamsters. Journal of Dental Research. 23:1944;439-444.
7. Keyes P.H. Dental caries in the molar teeth of rats. II. A method for diagnosing and scoring several types of lesions simultaneously. Journal of Dental Research. 37:1958;1088-1099.
8. Keyes P.H., Jordan H.V. Periodontal lesions in the Syrian hamster. III. Findings related to an infectious and transmissible component. Archives of Oral Biology. 9:1964;377-400.
9. Nakahara K., Kawabata S., Ono H., Ogura K., Tanaka T., Ooshima T., Hamada S. Inhibitory effect of oolong tea polyphenols on glucosyltransferases of mutans streptococci. Applied Environmental Microbiology. 59:1993;968-973.
10. Ooshima T., Fujiwara T., Takei T., Izumitani A., Sobue S., Hamada S. The caries inhibitory effects of GOS-sugar in vitro and in rat experiments. Microbiology and Immunology. 32:1988;1093-1105.
11. Ooshima T., Minami T., Aono W., Izumitani A., Sobue S., Fujiwara T., Kawabata S., Hamada S. Oolong tea polyphenols inhibit experimental dental caries in SPF rats infected with mutans streptococci. Caries Research. 27:1993;124-129.
12. Ooshima T., Izumitani A., Sobue S., Okahashi N., Hamada S. Non-cariogenicity of the disaccharide palatinose in experimental dental caries of rats. Infection and Immunity. 39:1983;43-49.
13. Ooshima T., Sobue S., Hamada S., Kotani S. Susceptibility of rats, hamsters, and mice to carious infection by Streptococcus mutans serotype c and d organisms. Journal of Dental Research. 60:1981;855-859.
14. Otake S., Makimura M., Kuroki T., Nishihara Y., Hirasawa M. Anticaries effects of polyphenolic compounds from Japanese green tea. Caries Research. 25:1991;438-443.
15. Regolati B., Hotz P. Cariostatic effect of glycerophosphate. Helvetica Odontologica Acta. 16:1972;13-18.
16. Rosenberg M., Gutnick D., Rosenberg E. Adherence of bacteria to hydrocarbons: simple method for measuring cell-surface hydrophobicity. FEMS Microbiology Letters. 9:1980;29-33.
17. Sakanaka S., Kim M., Taniguchi M., Yamamoto T. Antibacterial substances in Japanese green tea extract against Streptococcus mutans, a cariogenic bacterium. Agriculture Biological Chemistry. 53:1989;2307-2311.
18. Swain T., Hills W.E. Phenolic constituents of Prunus domestica. I. Quantative analysis of phenolic constituents. Journal of Science and Food Agriculture. 10:1959;63-68.
19. Wu-Yuan C.D., Chen C.Y., Wu R.T. Gallotannins inhibit growth, water-insoluble glucan synthesis, and aggregation of mutans streptococci. Journal of Dental Research. 67:1988;51-55.