Correlating the severity of paraquat poisoning with specific hemodynamic and oxygen metabolism variables

Critical Care Medicine

Volumn 28, Issue 6, 2000, Pages 1877-1883

  Yamamoto, Isotoshi ^a   Saito, Takeshi ^a   Harunari, Nobuyuki ^b   Sato, Yoji ^c   Kato, Hirotaka ^a   Nakagawa, Yoshihide ^a   Inokuchi, Sadaki ^a   Sawada, Yuhsuke ^a   Makuuchi, Hiroyasu ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHUKYO HOSPITAL   (Japan)

^c DOKKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cardiac output; Hyperdynamic state; Oxygen consumption; Oxygen delivery; Oxygen extraction; Oxygen metabolism; Paraquat poisoning; Severity index; Severity index of paraquat poisoning; Systemic vascular resistance

Indexed keywords

OXYGEN; PARAQUAT;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DISEASE SEVERITY; FEMALE; HEART INDEX; HEART OUTPUT; HEART WORK; HEMODYNAMICS; HUMAN; MALE; OXYGEN CONSUMPTION; PARAQUAT POISONING; PRIORITY JOURNAL; SURVIVAL TIME; SYSTEMIC VASCULAR RESISTANCE;

EID: 0033931346     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200006000-00032     Document Type: Article

References (39)

1. 1. Crome P: Paraquat poisoning 1986. Lancet 1988; 1:333-334
2. 2. Vale JA, Meredith TJ, Buckley BM: Paraquat poisoning: clinical feature and immediate general management. Human Toxicol 1987; 6:41-47
3. 3. Sawada Y, Yamamoto I, Hirokane T, et al: Severity index of paraquat poisoning. Lancet 1988; i:1333
4. 4. Hirai K, Witsch H, Cote MG: Mitochondrial injury of pulmonary alveolar epithelial cells in acute paraquat intoxication. Exp Mol Pathol 1985; 43:242-252
5. 5. Yamamoto I, Sawada U, Ueyama M, et al: A clinical study of pulmonary edema on paraquat poisoning by double indicator dilution method using heat sodium [summary in English]. Kokyu To Junkan 1989; 37:517-521
6. 6. Smith LL: Mechanism of paraquat toxicity in lung and its relevance to treatment. Toxicol 1987; 6:31-36
7. 7. Bus JS, Aust SD, Gibson JE: Superoxide-and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl xiologen) toxicity. Biochem Biophys Res Commun 1974; 58:749-755
8. 8. Bus JS, Aust SD, Gibson JE: Lipid peroxidation: A possible mechanism for paraquat toxicity. Res Commun Chem Pathol Pharmacol 1975; 11:31-38
9. 9. Baldwin RC, Pasi A, MacGregor JT, et al: The rates of radical formation from the dipyridilium herbicides, paraquat, diquat and morfamquat in homogenates of rat lung kidney and liver. Toxicol Appl Pharmacol 1975; 32: 298-304
10. 10. Hirai k, Ikeda K, Wang GY: Praquat damage of rat liver mitochondrial by superoxide production depends on extramitochondrial NADH. Toxicology 1992; 72:1-16
11. 11. Costantini P, Petronilli V, Colonna R, et al: On the effects of paraquat on isolated mitochondria: Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide. Toxicology 1995; 99:77-88
12. 12. Ernstoff JJ, Howard DA, Marshall JB, et al: A randomized blinded clinical trial of rapid colonic lavage solution (Golytely) compared with standard preparation for colonoscopy and barium enema. Gastroenterology 1983; 84:1512-1516
13. 13. Knepil J: A short, simple method for the determination of paraquat in plasma. Clin Chim Acta 1977; 79:387-390
14. 14. Madhu C, Gregus Z, Klaassen CD: Simple method for analysis of diquat in biological fluids and tissues by high-performance liquid chromatography. J Chromatogr B Biomed Appl 1995; 674:193-196
15. 15. Proudfoot AT, Stewart MJ, Levitt T, et al: Paraquat poisoning: Significance of plasma-paraquat concentration. Lancet 1979; 2:330-332
16. 16. Yoshioka T, Sugimoto T, Kinoshita N, et al: Effects of concentration reduction and partial replacement of paraquat by diquat on human toxicity: A clinical survey. Hum Exp Toxicol 1992; 11:241-245
17. 17. Wrong RC, Stevens JB: Bipyridylium herbicide toxicity in vitro: Comparative study of the cytotoxicity of paraquat and diquat toward the pulmonary alveolar macrophage. J Toxicol Environ Health 1986; 18:393-407
18. 18. Nagi AH: Paraquat and adrenal cortical necrosis. BMJ 1970; 13:669
19. 19. Parkinson C: The changing patterns of paraquat poisoning in man. Histopathology 1980; 4:171-183
20. 20. Reif RM, Lewinsohn G: Paraquat myocarditis and adrenal cortical necrosis. J Forensic Sci 1983; 28:505-509
21. 21. Webb DB, Leopord JD: Vasodilation and rehydration in paraquat poisoning. Hum Toxicol 1983; 3:531-534
22. 22. Sone T, Talbot A, Harada T, et al: The effect of 24% paraquat (1,1′-dimethyl-4,4′-bipyridylium dichloride) on hemodynamics, blood gases, plasma lactate and plasma catecholamines in dogs. Vet Hum Toxicol 1989; 31:149-153
23. 23. Sato Y, Yamamoto I, Sawada Y, et al: Hemodynamics of paraquat poisoning in acute phase [summary in English]. J Clin Exp Med 1987; 143:867-868
24. 24. Jain A, Shroff SG, Janicki JS, et al: Relation between mixed venous oxygen saturation and cardiac index. Chest 1991; 99:1403-1409
25. 25. Inoue T, Morooka S, Sakai Y, et al: Oxygen demand-supply relationship in peripheral tissues as a therapeutic indicator in acute myocardial infarction with advanced heart failure. Cardiology 1993; 82:30-35
26. 26. Silance PG, Simon C, Vincent JL: The relation between cardiac index and oxygen extraction in acutely ill patients. Chest 1994; 105:1190-1197
27. 27. Astiz ME, Rackow EC, Falk JL, et al: Oxygen delivery and consumption in patients with hyperdynamic septic shock. Crit Care Med 1987; 15:26-28
28. 28. Schumaker PT, Samsel RD: Oxygen delivery and uptake by peripheral tissues physiology and pathology. Crit Care Clin 1989; 5:255-267
29. 29. Herbertson MJ, Werner HA, Russell JA, et al: Myocardial oxygen extraction ratio is decreased during endotoxemia in pigs. J Appl Physiol 1995; 79:479-486
30. 30. Hayes MA, Timmins AC, Yau EH, et al: Oxygen transport patterns in patients with sepsis syndrome or septic shock: Influence of treatment and relationship to outcome. Crit Care Med 1997; 25:926-936
31. 31. Ciocca RG, Wilkerson DK, Conway RS, et al: Increased oxygen extraction as adaption to acute renal ischemia. J Invest Surg 1994; 7:519-526
32. 32. Samsel R, Nelson D, Sanders W, et al: Effect of endotoxin on systemic and skeletal muscle oxygen extraction. J Appl Physiol 1988; 65: 1377-1382
33. 2 uptake during endotoxemia. J Appl Physiol 1988; 64:2410-2419
34. 34. Rackow EC, Astiz ME, Weil MH: Cellular oxygen metabolism during sepsis and shock: The relationship of oxygen consumption to oxygen delivery. JAMA 1988; 259:1989-1993
35. 35. Asitz ME, Backow EC, Kaufman B, et al: Relationship of oxygen delivery and mixed venous oxygenation to lactic acidosis in patients with sepsis and acute myocardial infarction. Crit Care Med 1988; 16:655-658
36. 36. Bakker J, Coffernils M, Leon M, et al: Blood lactate levels are superior to oxygen derived variables in predicting outcome in human septic shock. Chest 1991; 99:956-962
37. 37. Parker MM, Suffredini AF, Natanson C, et al: Response of left ventricular function in survivors and nonsurvivors of septic shock. J Crit Care 1989; 4:19-25
38. 38. Vincent JL, Gris P, Coffernils M, et al: Myocardial depression characterize the fatal course of sepsis shock. Surgery 1992; 111: 660-667
39. 39. Shimada H, Hirai K, Simamura E, et al: Mitochondrial NADH-quinone oxidoreductase of the outer membrane is responsible for paraquat cytotoxicity in rat livers. Arch Biochem Biophys 1998; 351:75-81