Characterization of the α2-adrenoceptor subtype, which functions as α2-autoreceptor in human neocortex

Journal of Pharmacology and Experimental Therapeutics

Volumn 294, Issue 1, 2000, Pages 356-362

  Feuerstein, Thomas J ^a   Huber, Boris ^a   Vetter, Jan ^a   Aranda, Heike ^a   Van Velthoven, Vera ^a   Limberger, Norbert ^a,b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; AUTORECEPTOR; NORADRENALIN;

ADULT; AGED; ARTICLE; BINDING AFFINITY; FEMALE; HUMAN; HUMAN TISSUE; MALE; NEOCORTEX; NORADRENALIN RELEASE; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RECEPTOR BLOCKING; RECEPTOR DOWN REGULATION;

ADRENERGIC ALPHA-ANTAGONISTS; ADULT; AGED; AGED, 80 AND OVER; AUTORECEPTORS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOCORTEX; NOREPINEPHRINE; RECEPTORS, ADRENERGIC, ALPHA-2;

EID: 0033931278     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Agneter E, Singer EA, Sauermann W and Feuerstein TJ (1997) The slope parameter of concentration-response curves used as a touchstone for the existence of spare receptors. Naunyn-Schmiedeberg's Arch Pharmacol 356:283-292.
2. 3H]-noradrenaline release in rabbit hippocampus and human neocortex. Br J Pharmacol 116:1769-1774.
3. Altman DG (1991) Statistics in medical journals: Developments in the 1980s. Stat Med 10:1897-1913.
4. 2A-adrenergic receptor knockout mice. Mol Pharmacol 58:154-161.
5. 2C adrenergic receptor subtype in the opossum kidney and in the OK cell line. J Pharmacol Exp Ther 259:323-329.
6. 2 adrenergic receptor subtypes. Ann NY Acad Sci 763:1-7.
7. 2-adrenergic receptors: Comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning. Mol Pharmacol 42:1-5.
8. 2-adrenoceptors. Eur J Pharmacol 361:1-15.
9. Feuerstein TJ, Dooley DJ and Seeger W (1990) Inhibition of norepinephrine and acetylcholine release from human neocortex by ω-conotoxin GVIA. J Pharmacol Exp Ther 252:778-785.
10. Feuerstein TJ and Limberger N (1999) Mathematical analysis of the control of neurotransmitter release by presynaptic receptors as a supplement to experimental data. Naunyn-Schmiedeberg's Arch Pharmacol 359:349-359.
11. 2-adrenoceptors on serotonergic nerve endings in human and rat neocortex. J Neurochem 61:474-480.
12. Feuerstein TJ, Sauermann W, Allgaier C and Singer EA (1993b) Mathematical modelling and quantification of the autoinhibitory feedback control of noradrenaline release in brain slices. Naunyn-Schmiedeberg's Arch Pharmacol 347:171-179.
13. Goodall J, Hagan RM and Hughes IE (1984) A contribution, from a possible local anaesthetic action, to the effects of yohimbine on evoked noradrenaline overflow. J Pharm Pharmacol 36:278-280.
14. 2-adrenoceptor mediating prejunctional inhibition in rat atrium and cerebral cortex. Naunyn-Schmiedeberg's Arch Pharmacol 357:634-639.
15. Jackisch R, Kruchen A, Sauermann W, Hertting G and Feuerstein TJ (1994) The antiparkinsonian drugs budipine and biperiden are use-dependent (uncompetitive) NMDA receptor antagonists. Eur J Pharmacol 264:207-211.
16. 2A-Autoreceptors in rabbit atria and kidney. Naunyn-Schmiedeberg's Arch Pharmacol 352:31-42.
17. 2D-Autoreceptors in mouse brain. Naunyn-Schmiedeberg's Arch Pharmacol 352:43-48.
18. 2-autoreceptors in the rabbit pulmonary artery and human saphenous vein. Naunyn-Schmiedeberg's Arch Pharmacol 352:483-490.
19. 2A adrenergic receptor: The pharmacological properties of the bovine and rat receptors differ from the human and porcine receptors. J Pharmacol Exp Ther 271:735-740.
20. 2-autoreceptors in human brain cortex. Br J Pharmacol 107:1146-1151.
21. 2C-Adrenoceptor-modulated release of noradrenaline in human right atrium. Br J Pharmacol 116:2617-2624.
22. Segel IH (1975) Uncompetitive inhibition (simple linear uncompetitive inhibition), in Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Segel IH ed) pp 136-143, John Wiley and Sons, New York.
23. 2D-adrenergic receptors in bovine pineal gland. Mol Pharmacol 40:235-241.
24. Singer EA (1988) Transmitter release from brain slices elicited by single pulses: A powerful method to study presynaptic mechanisms. Trends Pharmacol Sci 9:274-276.
25. 2A/D-adrenoceptor-deficient mice. Naunyn-Schmiedeberg's Arch Pharmacol 360:540-551.
26. 2C subtype mediate inhibition of norepinephrine release in human kidney cortex. Mol Pharmacol 45:1168-1176.
27. 2A in the rabbit. Naunyn-Schmiedeberg's Arch Pharmacol 348:35-45.
28. 2-autoreceptors: Rat vena cava, rat atria, human kidney and guinea-pig urethra. Naunyn-Schmiedeberg's Arch Pharmacol 356:721-737.