Polymorphisms in the genes encoding platelet-derived growth factor A and α receptor

Journal of Molecular Medicine

Volumn 78, Issue 5, 2000, Pages 287-292

  Herrmann, Stefan Martin ^a,f   Ricard, Sylvain ^a   Nicaud, Viviane ^a   Brand, Eva ^a   Behague, Isabelle ^a   Blanc, Hervé ^a   Ruidavets, Jean Bernard ^b   Evans, Alun ^c   Arveiler, Dominique ^d   Luc, Gerald ^e   Poirier, Odette ^a   Cambien, François ^a  

^a Moleculaire des Patholo C   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e INSTITUT PASTEUR DE LILLE   (France)

^f FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Case control study; Genetic polymorphism; Myocardial infarction; Platelet derived growth factor; Platelet derived growth factor receptor

Indexed keywords

PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR RECEPTOR; TRANSCRIPTION FACTOR;

ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; GENETIC CODE; GENETIC POLYMORPHISM; GENOTYPE; HEART INFARCTION; HETEROZYGOSITY; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0033930256     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090000111     Document Type: Article

References (36)

1. 1. Ross R, Raines EW, Bowen-Pope DF (1986) The biology of platelet-derived growth factor. Cell 46:155-169
2. 2. Ross R (1993) The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362:801-809
3. 3. Heldin CH, Backstrom G, Ostman A, Hammacher A, Ronnstrand L, Rubin K, Nister M, Westermark B (1988) Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types. EMBO J 7:1387-1393
4. 4. Antoniades HN (1981) Human platelet-derived growth factor (PDGF). Purification of PDGF-I and PDGF-II and separation of their reduced subunits. Proc Natl Acad Sci USA 78:7314-7317
5. 5. Wang ZY, Deuel TF (1992) An S1 nuclease-sensitive homopurine/homopyrimidine domain in the PDGF A-chain promoter contains a novel binding site for the growth factor-inducible protein EGR-1. Biochem Biophys Res Commun 188:433-439
6. 6. Seifert RA, Hart CE, Phillips PE, Forstrom JW, Ross R, Murray MJ, Bowen-Pope DF (1989) Two different subunits associate to create isoform-specific platelet-derived growth factor receptors. J Biol Chem 264:8771-8778
7. 7. Bonthron DT, Morton CC, Orkin SH, Collins T (1988) Platelet-derived growth factor A chain: gene structure, chromosomal location, and basis for alternative mRNA splicing. Proc Natl Acad Sci U S A 85:1492-1496
8. 8. Rorsman F, Bywater M, Knott TJ, Scott J, Betsholtz C (1988) Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins. Mol Cell Biol 8:571-577
9. 9. Claesson-Welsh L, Hammacher A, Westermark B, Heldin CH, Nister M (1989) Identification and structural analysis of the A type receptor for platelet-derived growth factor. Similarities with the B type receptor. J Biol Chem 264:1742-1747
10. 10. Claesson-Welsh L, Eriksson A, Moren A, Severinsson L, Ek B, Ostman A, Betsholtz C, Heldin CH (1988) cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules. Mol Cell Biol 8:3476-3486
11. 11. Hart CE, Forstrom JW, Kelly JD, Seifert RA, Smith RA, Ross R, Murray MJ, Bowen-Pope DF (1988) Two classes of PDGF receptor recognize different isoforms of PDGF. Science 240: 1529-1531
12. 12. Afink GB, Nister M, Stassen BH, Joosten PH, Rademakers PJ, Bongcam-Rudloff E, Van Zoelen EJ, Mosselman S (1995) Molecular cloning and functional characterization of the human platelet-derived growth factor alpha receptor gene promoter. Oncogene 10:1667-1672
13. 13. Matsui T, Heidaran M, Miki T, Popescu N, La Rochelle W, Kraus M, Pierce J, Aaronson S (1989) Isolation of a novel receptor cDNA establishes the existence of two PDGF receptor genes. Science 243:800-804
14. 14. Claesson-Welsh L, Eriksson A, Westermark B, Heldin CH (1989) cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor. Proc Natl Acad Sci U S A 86:4917-4921
15. 15. Parra HJ, Arveiler D, Evans AE, Cambou JP, Amouyel P, Bingham A, McMaster D, Schaffer P, Douste-Blazy P, Luc G, Richard JL, Ducimetiere P, Fruchart JC, Cambien F (1992) A case-control study of lipoprotein particles in two populations at contrasting risk for coronary heart disease. The ECTIM Study. Arterioscler Thromb 12:701-707
16. 16. Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Bard JM, Bara L, Ricard S, Tiret L, Amouyel P, Alhenc-Gelas F, Soubrier F (1992) Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359:641-644
17. 17. Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T (1989) Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci U S A 86:2766-2770
18. 18. Saiki RK, Bugawan TL, Horn GT, Mullis KB, Erlich HA (1986) Analysis of enzymatically amplified beta-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probes. Nature 324:163-166
19. 19. Herrmann SM, Ricard S, Nicaud V, Mallet C, Evans A, Ruidavets JB, Arveiler D, Luc G, Cambien F (1998) The P-selectin gene is highly polymorphic: reduced frequency of the Pro715 allele carriers in patients with myocardial infarction. Hum Mol Genet 7:1277-1284
20. 20. Tiret L, Amouyel P, Rakotovao R, Cambien F, Ducimetiere P (1991) Testing for association between disease and linked marker loci: a log-linear-model analysis. Am J Hum Genet 48:926-934
21. 21. Nei M (1987) Molecular evolutionary genetics. Columbia University Press, New York
22. 22. Schattemann GC, Loushin C, Li T, Hart CE (1996) PDGF-A is required for normal murine cardiovascular development. Dev Biol 176:133-142
23. 23. Jawien A, Bowen-Pope DF, Lindner V, Schwartz SM, Clowes AW (1992) Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty. J Clin Invest 89:507-511
24. 24. Libby P, Warner SJ, Salomon RM, Birinyi LK (1988) Production of platelet-derived growth factor-like mitogen by smooth-muscle cells from human atheroma. N Engl J Med 318:1493-1498
25. 25. Wilcox JN, Smith KM, William LT, Schwartz SM, Gordon D (1988) Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization. J Clin Invest 82:1134-1143
26. 26. Hachida M, Zhang X, Lu H, Hoshi H, Furutani Y, Matsuoka R, Koyganagi H (1998) Association between degree of platelet-derived growth factor-A chain mRNA expression and coronary arteriosclerosis in the transplanted heart. Heart Vessels 13:24-29
27. 27. Khachigian LM, Anderson KR, Halnon NJ, Gimbrone MAJ, Resnick N, Collins T (1997) Egr-1 is activated in endothelial cells exposed to fluid shear stress and interacts with a novel shear-stress-response element in the PDGF A-chain promoter. Arterioscler Thromb Vasc Biol 17:2280-2286
28. 28. Schwartz SM, deBlois D, O'Brien ER (1995) The intima. Soil for atherosclerosis and restenosis. Circ Res 77:445-465
29. 29. Rekhter MD, Gordon D (1994) Does platelet-derived growth factor-A chain stimulate proliferation of arterial mesenchymal cells in human atherosclerotic plaques? Circ Res 75:410-417
30. 30. Zwijsen RM, Japenga SC, Heijen AM, van den Bos RC, Koeman JH (1992) Induction of platelet-derived growth factor chain A gene expression in human smooth muscle cells by oxidized low density lipoproteins. Biochem Biophys Res Commun 186:1410-1416
31. 31. Ferns GA, Raines EW, Sprugel KH, Motani AS, Reidy MA, Ross R (1991) Inhibition of neointimal smooth muscle cell accumulation after angioplasty by an antibody to PDGF. Science 253:1129-1132
32. 32. Buchman C, Skroch P, Dixon W, Tullius TD, Karin M (1990) A single amino acid change in CUP2 alters its mode of DNA binding. Mol Cell Biol 10:4778-4787
33. 33. Kageyama R, Pastan I (1989) Molecular cloning and characterization of a human DNA binding factor that represses transcription. Cell 59:815-825
34. 34. Kadonaga JT, Carner KR, Masiarz FR, Tjian R (1987) Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain. Cell 51:1079-1090
35. 35. Kageyama R, Merlino GT, Pastan I (1988) Epidermal growth factor (EGF) receptor gene transcription. Requirement for Sp1 and an EGF receptor-specific factor. J Biol Chem 263:6329-6336
36. 36. Cambien F, Poirier O, Nicaud V, Herrmann SM, Mallet C, Ricard S, Behague I, Hallet V, Blanc H, Loukaci V, Thillet J, Evans A, Ruidavets JB, Arveiler D, Luc G, Tiret L (1999) Sequence diversity in 36 candidate genes for cardiovascular disorders. Am J Hum Genet 65:183-191