Expression of the genetic variants of human alpha-1-acid glycoprotein in cancer

Clinical Biochemistry

Volumn 33, Issue 3, 2000, Pages 197-202

  Duché, Jean Claude ^a   Urien, Saïk ^a   Simon, Nicolas ^a   Malaurie, Emmanuelle ^a   Monnet, Isabelle ^a   Barré, Jérôme ^a  

^a CENTRE HOSPITALIER INTERCOMMUNAL DE CRÉTEIL   (France)

Author keywords

Alpha 1 acid glycoprotein; Cancer patients; Genetic variants

Indexed keywords

OROSOMUCOID;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER; CONTROLLED STUDY; FEMALE; GENETIC VARIABILITY; HUMAN; IMMUNOBLOTTING; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; NEPHELOMETRY; OVARY CANCER; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION; HUMANS; ISOELECTRIC FOCUSING; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEPHELOMETRY AND TURBIDIMETRY; OROSOMUCOID; OVARIAN NEOPLASMS; POLYMORPHISM, GENETIC; STATISTICS, NONPARAMETRIC; VARIATION (GENETICS);

EID: 0033929869     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(00)00048-5     Document Type: Article

References (19)

1. Kremer J.M.H., Wilting J., Janssen L.M.H. Drug binding to human alpha-1-acid glycoprotein in health and disease. Pharmacol Rev. 40:1988;1-47.
2. Routledge P.A. Clinical relevance of alpha-1-acid glycoprotein in health and disease. Baumann P., Eap C.B., Müller W.E., Tillement J.P. Alpha-1-acid glycoprotein. Genetics, biochemistry, physiological functions and pharmacology. 1989;185-198 Alan R. Liss, New York.
3. Schmid K. Human plasma alpha-1-acid glycoprotein Biochemical properties, the amino acid sequence and the structure of the carbohydrate moiety, variants and polymorphism . Baumann P., Eap C.B., Müller W.E., Tillement J.P. Alpha-1-acid glycoprotein. Genetics, biochemistry, physiological functions and pharmacology. 1989;7-22 Alan R. Liss, New York.
4. Yuasa I., Weidinger S., Umetsu K., et al. Orosomucoid system 17 additional orosomucoid variants and proposal for a new nomenclature . Vox Sang. 64:1993;47-55.
5. Eap C.B., Cuendet C., Baumann P. Binding of d-methadone, l-methadone and dl-methadone to proteins in plasma of healthy volunteers Role of the variants of alpha-1-acid glycoprotein . Clin Pharmacol Ther. 47:1990;338-346.
6. Weidinger S., Müller T., Schwarzfischer F., Cleve H. Three new orosomucoid (ORM) variants revealed by isoelectric focusing and print immunofixation. Hum Genet. 77:1987;286-288.
7. Eap C.B., Baumann P. Genetic polymorphism of human alpha-1-acid glycoprotein. Baumann P., Eap C.B., Müller W.E., Tillement J.P. Alpha-1-acid glycoprotein. Genetics, biochemistry, physiological functions and pharmacology. 1989;111-125 Alan R. Liss, New York.
8. Dente L., Pizza M.G., Metspalu A., Cortese R. Structure and expression of the genes coding for human AAG. EMBO J. 6:1987;2289-2296.
9. Tomei L., Eap C.B., Baumann P., Dente L. Use of transgenic mice for characterization of human alpha-1-acid glycoprotein (orosomucoid) variants. Hum Genet. 84:1989;89-91.
10. Schreiber G. Synthesis, processing and secretion of plasma proteins by liver and other organs and their regulation. Plasma proteins. 5:1987;293-363.
11. Eap C.B., Fischer J.F., Baumann P. Variations in relative concentrations of variants of alpha-1-acid glycoprotein. Clin Chim Acta. 203:1991;379-386.
12. Van Dijk W., Pos O., van der Stelt M.E., et al. Inflammation-induced changes in expression and glycosylation of genetic variants of α-1-acid glycoprotein. Studies with human sera, primary cultures of human hepatocytes and transgenic mice. Biochem J. 276:1991;343-348.
13. Duché J.C., Hervé F., Tillement J.P. Study of the expression of the genetic variants of human alpha-1-acid glycoprotein in healthy subjects using isoelectric focusing and immunoblotting. J Chromatogr. 715:1998;103-109.
14. Eap C.B., Baumann P. Isoelectric focusing of alpha-1-acid glycoprotein (orosomucoid) in immobilized pH-gradients with 8 M urea Detection of its desialylated variants using an alkaline phosphatase-linked secondary antibody system . Electrophoresis. 9:1988;650-654.
15. Mittermüller J., Weidinger S. Genetic study of orosomucoid by isoelectric focusing and immunoprinting in patients with carcinoma. Electrophoresis. 13:1992;785-786.
16. Fan C., Stendahl U., Stjernberg N., Beckman L. Association between orosomucoid types and cancer. Oncology. 52:1995;498-500.
17. Hervé F., Duché J.C., Jaurand M.C. Changes in expression and microheterogeneity of the genetic variants of human α-1-acid glycoprotein in malignant mesothelioma. J Chromatogr. 715:1998;111-123.
18. Tiula E., Neuvonen P.J. Antiepileptic drugs and α1 acid glycoprotein. N Engl J Med. 307:1982;1148.
19. Baumann P., Tinguely D., Schöpf J. Increase of α1 acid glycoprotein after treatment with amitriptyline. Br J Clin Pharm. 14:1982;102-103.