Design of new analogues of glutamic acid with a conformationally restricted structure

Farmaco

Volumn 55, Issue 3, 2000, Pages 162-164

  Conti, Paola ^a   De Amici, Marco ^a   De Micheli, Carlo ^a  

^a Istituto di Chimica Farmaceutica e Tossicologica   (Italy)

Author keywords

AMPA agonists; Convulsant activity; Glutamate receptors; Isoxazolinylprolines; Kainic acid agonists

Indexed keywords

3 CARBOXYISOXAZOLINYLPROLINE DERIVATIVE; 3 HYDROXYISOXAZOLINYLPROLINE DERIVATIVE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; CONVULSANT AGENT; GLUTAMATE RECEPTOR; GLUTAMIC ACID DERIVATIVE; ISOXAZOLINE DERIVATIVE; KAINIC ACID; KAINIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BRAIN CORTEX; CONFERENCE PAPER; CONTROLLED STUDY; CONVULSION; DRUG CONFORMATION; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; MOUSE; NONHUMAN; RAT; SECOND MESSENGER; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; DRUG DESIGN; EXCITATORY AMINO ACID AGONISTS; GLUTAMATES; MICE; MOLECULAR CONFORMATION; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033929150     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(00)00011-2     Document Type: Article

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