The effects of exercise training intensification on glucose disposal in elite cyclists

International Journal of Sports Medicine

Volumn 21, Issue 5, 2000, Pages 338-343

  Manetta, J ^a   Brun, J F ^a   Mercier, J ^a   Prefaut, C ^a  

^a LAPEYRONIE HOSPITAL   (France)

Author keywords

Exercise training; Glucose uptake; Insulin sensitivity; Minimal model

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; CYCLING; EXERCISE; GLUCOSE TRANSPORT; HUMAN; HUMAN EXPERIMENT; INSULIN SENSITIVITY; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MODEL;

ADULT; BICYCLING; CASE-CONTROL STUDIES; ENERGY METABOLISM; GLUCOSE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; PHYSICAL ENDURANCE;

EID: 0033928285     PISSN: 01724622     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-3781     Document Type: Article

References (36)

1. 1 Astrand PO, Rodahl K. Physiological basis of exercise. Textbook of work physiology; 3rd ed. New York: MacGraw Hill, 1986
2. 2 Bergman RN, Ider YZ, Bowden CR, Cobelli C. Quantitative estimation of insulin sensitivity. Am J Physiol 1979; 236: E667-E677
3. 3 Bergman RN, Finegood DT, Adler M. Assessment of insulin sensitivity in vivo. Endocr Rev 1985; 6: 45-86
4. 4 Bouix O, Brun JF, Orsetti A. The magnitude, the kinetics and the metabolic efficiency of first-phase insulin response to intravenous glucose are related. Horm Metab Res 1993; 25: 312-316
5. 5 Brun JF, Boegner C, Orsetti A. Le minimal model: un nouvel outil pour l'etude des hypoglycémies du sportif. Sci Sports 1994; 9: 47-49
6. 6 Brun JF, Guintrand-Hugret R, Boegner C, Bouix O, Orsetti A. Influence of short submaximal exercise on parameters of glucose assimilation analyzed with minimal model. Metabolism 1995; 44: 833-840
7. 7 Brun JF, Bouix O, Monnier JF, Blanchon P, Jourdan N, Baccara MT, Fedou C, Orsetti A. Increased insulin sensitivity and basal insulin effectiveness in postprandial reactive hypoglycaemia. Acta Diabetologica 1996; 33: 1-6
8. 8 Brooks GA, Mercier J. Balance of carbohydrate and lipid during exercise: the 'crossover' concept. J Appl Physiol 1994; 76: 2253-2261
9. 9 Douen AG, Ramlal T, Rastogi S. Exercise induces recruitment of the insulin-responsive glucose transporter. Evidence for distinct intracellular insulin-and exercise-recruitable transporter pools in skeletal muscle. J Biol Chem 1990; 265: 13427-13430
10. 10 Engfred K, Kjaer M, Secher NH, Friedman DB. Hypoxia and training-induced adaptation of hormonal responses to exercise in humans. Eur J Appl Physiol 1990; 68: 303-309
11. 11 Finegood DT, Tzur D. Reduced glucose effectiveness associated with reduced insulin release: an artifact of the minimal model method. Am J Physiol 1996; 271: E485-E495
12. 12 Houmard JA, Egan PC, Neufer PD, Friedeman JE, Wheeler WS, Israel RG. Elevated skeletal muscle glucose transporter levels in exercise-trained middle-aged men. Am J Physiol (Endocrinol Metab. 24) 1991; 261: E437-E443
13. 13 Khan SE, Bergman RN, Schwartz MW, Taborsky GJ. Porte D Jr. Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans. Am J Physiol 1992; 262: E518-E523
14. 14 Klip A, Marette A. Acute and chronic signals controlling glucose transport in skeletal muscle. J Cell Biochem 1992; 48: 51-60
15. 15 Koivisto VA, Yki-Järvinen A, DeFronzo R. Physical training and insulin sensitivity. Diabetes Metab Rev 1986; 1: 445-481
16. 16 Lukaski HC, Johnson PE, Bolonchuch WW, Lykken V. Assessment of fat-free mass using bioelectrical impedance measurements of the human body. Am J Clin Nutr 1985; 41: 810-817
17. 17 Manetta J, Khaled S, Bouix D, Krechiem K, Brun JF, Orsetti A. Evaluation d'un questionnaire alimentaire court par comparaison avec un entretien diététique chez des sujets sportifs et sédentaires. Sci Sport 1997; 12: 210-213
18. 18 Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419
19. 19 Mikines KJ, Sonne B, Farrel PA. Effect of physial exercise on sensitivity and responsiveness to insulin in humans. Am J Physiol 1988; 254: E248-E259
20. 20 Monnier JF, Raynaud E, Brun JF, Orsetti A. Evaluation de la répétabilité moyenne d'une technique d'impédancemétrie appliquée à la détermination de la composition corporelle. Sci Sports 1997; 12: 208-209
21. 21 Ni TC, Ader M, Bergman RN. Reassessment of glucose effectiveness and insulin sensitivity from minimal model analysis. A theoretical evaluation of the single compartment glucose distribution assumption. Diabetes 1997; 46: 1813-1821
22. 22 Oja P, Laukkanen RM, Kukkonen-Harjula TK, Vuori IM. Training effect of cross country skiing and running on maximal aerobic cycle performance and blood lipids. Eur J Appl Physiol 1991; 62: 400-404
23. 23 Orsetti A, Brun JF, Galtier-Dereure F. Effect de l'obésité sur l'insulino-résistance des DNIDs et des sujets non diabétiques. ALFE-DIAM Paris: Diabete & Metabolisme, 1996
24. 24 Ploug T, StallKnecht BM, Pedersen O, Khan BB, Ohkuwa T, Vinten J, Galbo H. Effect of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle. Am J Physiol 1990; 259: E778-E786
25. 25 Quon MJ, Cochran C, Taylor SI, Eastman RC. Non-insulin-mediated glucose disappearance in subjects with IDDM: discordance between experimental results and minimal-model analysis. Diabetes 1994; 43: 890-896
26. 26 Rodnick KJ, Haskell WL, Swislocki A. Demonstration of a relationship between level of physical training and insulin-stimulated glucose utilisation in normal humans. Am J Physiol 1987; 253: E489-E495
27. 27 Rosenthal M, Haskell WL, Solomon R, Widstrom A, Reaven GM. Demonstration of a relationship between level of physical training and insulin-stimulated glucose utilisation in normal humans. Diabetes 1983; 32: 408-411
28. 28 Ruderman NB, Balton T, Zorzano A, Goodman M. The post-exercise state: altered effects of insulin on skeletal muscle and their physiologic relevance. Diabetes Metab Rev 1986; 1: 425-444
29. 29 Seals DR, Hagberg JM, Allen WK, Hurley BF, Dalsky GP, Ehsani A, Hollozy JO. Glucose tolerance in young and older athletes and sedentary men. J Appl Physiol 1984; 56: 1521-1525
30. 30 Steil GM, Bergman RM. Reduced sampling for the minimal model estimate of insulin sensitivity from the modified and standard frequency sampled IVGTT. Diabetes 1991; 40: 38A
31. 31 Tamburrano G, Leonetti F, Sbraccia P, Giaccari A, Locuratolo N, Lala A. Increased insulin sensitivity in patients with idiopathic reactive hypoglycemia. J Clin Endocrinol Metab 1989; 69: 885-891
32. 32 Tokuyama K, Higaki Y, Fujitani J, Kiyonaga A, Tanaka H, Shindo M, Fukushima M, Nakal Y, Imura H, Nagata I. Intravenous glucose tolerance test-derived glucose effectiveness in physically trained humans. Am J Physiol 1993; 265: E298-E303
33. 33 Walton C, Godland IF, Proudler J, Felton CV, Wynn V. Effect of body mass index and fat distribution on insulin sensitivity, secretion in nonobese healthy men. J Clin Endocr Metab 1990; 75: 170-175
34. 34 Wahlund H. Determination of physical working capacity. Acta Med Scand 1948; 215: 1-78
35. 35 Ward GM, Weber KM, Walters IM, Altken PM, Lee B, Best JD, Boston RC, Alford FP. A modified minimal model analysis of insulin sensitivity and glucose-mediated disposal in insulin-dependent diabetes. Metabolism 1991; 40: 4-9
36. 36 Yang YJ, Youn JA, Bergman RN. Modified protocols to improve insulin sensitivity estimation using the minimal model. Am J Physiol 1987; 253: E595-E602