Treatment of severe atopic dermatitis by topical immune modulation using dinitrochlorobenzene

Journal of the American Academy of Dermatology

Volumn 42, Issue 4, 2000, Pages 687-689

  Mills, L Bruce ^a,b   Mordan, Lawrence J ^b   Roth, Harry L ^c   Winger, Edward E ^d   Epstein, William L ^c  

^a Department of Dermatology ^*  (United States)

^b Research and Education Foundation   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Immunodiagnostic Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE;

ARTICLE; ATOPIC DERMATITIS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTACT SENSITIZATION; DRUG EFFICACY; HUMAN; IMMUNOMODULATION; PRIORITY JOURNAL; TREATMENT OUTCOME;

EID: 0033926848     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1067/mjd.2000.104518     Document Type: Article

References (10)

1. Grewe M, Bruijnzeel-Koomen CAFM, Schopf E, Thepen T, Langeveld-Wildschut AG, Ruzick T, et al. A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis. Immunol Today 1998;19:359-61.
2. Mills LB. Stimulation of T-cellular immunity by cutaneous application of dinitrochlorobenzene. J Am Acad Dermatol 1986;14: 1089-90.
3. Stricker RB, Goldberg B, Epstein WL. Topical immune modulation (TIM): a novel approach to the immunotherapy of systemic disease. Immunol Lett 1997;59:145-50.
4. Hanifin J, Rajka G. Proceedings of First International Conference on Atopic Dermatitis. Acta Derm Venereol Suppl (Stockh) 1980;92:44-7.
5. Hanifin JM, Schneider LC, Leung DYM, Ellis CN, Jaffe HS, Izu AE, et al. Recombinant interferon gamma therapy for atopic dermatitis. J Am Acad Dermatol 1993;28:189-97.
6. Reinhold U, Kukel S, Brzoska J, Kreysel HW. Systemic interferon gamma treatment in severe atopic dermatitis. J Am Acad Dermatol 1993;29:58-63.
7. Ruzicka T, Bieber T, Schopf E, Rubins A, Dobozy A, Bos JD, et al. A short-term trial of tacrolimus ointment for atopic dermatitis: European Tacrolimus Multicenter Atopic Dermatitis Study Group. N Engl J Med 1997;337:816-21.
8. Boguniewicz M, Fielder VC, Raimer S, Lawrence ID, Leung DYM, Hanafin JM. A randomized vehicle-controlled trial of tacrolimus ointment for treatment of atopic dermatitis in children. J Allergy Clin Immunol 1998;102:635-42.
9. Stricker RB, Goldberg B. Safety of topical Dinitrochlorobenzene. Lancet 1995;346:1293.
10. Lauerma AI, Maibach HI, Granlund H, Erkko P, Kartamaa M, Stubb S. Inhibition of contact allergy reactions by topical FK506 [letter]. Lancet 1992;340:8818.