Preparation of 4-hydroxy-2-trifluoromethylthiophene: A novel bioisostere of α,α,α-trifluoro-m-cresol

Synthesis

Volumn , Issue 8, 2000, Pages 1078-1080

  Karp, Gary M ^a   Samant, Dilip ^b   Mukhopadhyay, Sudarsan ^b   Condon, Michael E ^a   Kleemann, Axel ^c  

^a PFIZER INC   (United States)

^b Starks Associates Inc   (United States)

^c Cyanamid Forschung GmbH   (Germany)

Author keywords

Addition reactions; Bioisosteres; Cyclizations; Fiesselmann reaction; Thiophenes

Indexed keywords

CRESOL; PYRIDINE DERIVATIVE; THIOPHENE DERIVATIVE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; SYNTHESIS;

EID: 0033924888     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-6320     Document Type: Article

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