Physiological effects of extracellular nucleotides in the inner ear

Clinical and Experimental Pharmacology and Physiology

Volumn 27, Issue 8, 2000, Pages 575-580

  Housley, Gary D ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

ATP; Auditory neurotransmission; Cochlea; Hearing; P2X receptors; P2Y receptors; Purines; Sound transduction

Indexed keywords

ADENOSINE TRIPHOSPHATE; METABOTROPIC RECEPTOR;

ACOUSTIC NERVE FIBER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONTROLLED STUDY; DRUG EFFECT; ELECTROCHEMISTRY; ENZYME INHIBITION; GUINEA PIG; INNER EAR; NERVE CONDUCTION; NONHUMAN; NUCLEOTIDE METABOLISM; REVIEW; SIGNAL TRANSDUCTION; SMOOTH MUSCLE TONE; SOUND TRANSMISSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; EAR, INNER; EXTRACELLULAR SPACE; HUMANS; NUCLEOTIDES;

EID: 0033922997     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2000.03314.x     Document Type: Review

References (78)

1. 1. Abbracchio MP, Burnstock G. Purinergic signalling: Pathophysiological roles. Jpn. J. Pharmacol. 1998; 78: 113-45.
2. 2 receptor-channel activation and desensitization. Mol. Endocrinol. 1998; 12: 901-13.
3. 3. Thorne PR, Housley GD. Purinergic signalling in sensory systems. Semin. Neurosci. 1996; 8: 233-46.
4. 2 receptor subunit of the ATP-gated ion channel in the cochlea: Implications for sound transduction and auditory neurotransmission. J. Neurosci. 1999; 19: 8377-88.
5. 5. Chen C-C, Akoplan AN, Sivilotti L, Colquhoun D, Burnstock G, Wood JN. A P2x purinoceptor expressed by a subset of sensory neurons. Nature 1995; 377: 428-31.
6. 3 receptor subunits can account for ATP-gated currents in sensory neurons. Nature 1995; 377: 432-5.
7. 7. Burnstock G, Wood JN. Purinergic receptors: Their role in nociception and primary afferent neurotransmission. Curr. Opin. Neurobiol. 1996; 6: 526-32.
8. 8. Burnstock G. A unifying purinergic hypothesis for the initiation of pain. Lancet 1996; 347: 1604-5.
9. 3 receptor immunoreactive nerves in rat taste buds. Neuroreport 1999; 10: 1107-11.
10. 2 receptor subunit of the ATP-gated ion channels in the rat central nervous system. J. Comp. Neurol. 1999; 407: 11-32.
11. 2 receptor subunit of the ATP-gated ion channel in the retina. Neuroreport 1997; 8: 1083-8.
12. 12. Brändle U, Guenther E, Irrle C, Wheeler-Schilling TH. Gene expression of the P2X receptors in the rat retina. Mol. Brain Res. 1998; 59: 269-72.
13. 7-receptor subunit in neurons of the rat retina. Mol. Brain Res. 1998; 62: 106-9.
14. 2+-permeable P2X receptor channels in cultured rat retinal ganglion cells. J. Neurosci. 1999; 19: 3353-66.
15. 15. Housley GD. Extracellular nucleotide signaling in the inner ear. Mol. Neurobiol. 1998; 16: 21-48.
16. 3 receptors form stable trimers: A novel structural motif of ligand-gated ion channels. EMBO J. 1998; 17: 3016-28.
17. 17. Virginio C, MacKenzie A, Rassendren FA, North RA, Surprenant A. Pore dilation of neuronal P2X receptor channels. Nat. Neurosci. 1999; 2: 315-21.
18. 18. Khakh BS, Bao XR, Labarca C, Lester HA. Neuronal P2X transmittergated cation channels change their ion selectivity in seconds. Nat. Neurosci. 1999; 2: 322-30.
19. 6 channel subunits coassemble into a novel heteromeric ATP receptor. J. Neurosci. 1998; 18: 7152-9.
20. 20. Barnard EA, Burnstock G, Webb TE. G protein-coupled receptors for ATP and other nucleotides: A new receptor family. Trends Pharmacol. Sci. 1994; 15: 67-70.
21. 21. Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol. Rev. 1998; 50: 413-92.
22. 22. Boyer JL, Lazarowski ER, Chen XH, Harden TK. Identification of a P2Y-purinergic receptor that inhibits adenylyl cyclase. J. Pharmacol. Exp. Ther. 1993; 267: 1140-6.
23. 23. Ashmore JF, Ohmori H. Control of intracellular calcium by ATP in isolated outer hair cells of the guinea-pig cochlea. J. Physiol. 1990; 428: 109-31.
24. 24. Nakagawa T, Akaike N, Kimitsuki T, Komune S, Arima T. ATP-induced current in isolated outer hair cells of guinea pig cochlea. J. Neurophysiol. 1990; 63: 1068-74.
25. 25. Hoyle CHV. Purinergic cotransmission: Parasympathetic and enteric nerves. Semin. Neurosci. 1996; 8: 207-15.
26. 26. Housley GD, Greenwood D, Ashmore JF. Localization of cholinergic and purinergic receptors on outer hair cells isolated from the guinea-pig cochlea. Proc. R. Soc. Lond. B 1992; 249: 265-73.
27. 27. Elgoyhen AB, Johnson DS, Boulter J, Vetter DE, Heinemann S. Alpha 9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell 1994; 79: 705-15.
28. 28. Glowatzki E, Wild K, Brändle U et al. Cell-specific expression of the α9-ACh receptor subunit in auditory hair cells revealed by single-cell RT-PCR. Proc. R. Soc. Lond. B 1995; 262: 141-7.
29. 29. Luo L, Bennett T, Jung HH, Ryan AF. Developmental expression of alpha 9 acetylcholine receptor mRNA in the rat cochlea and vestibular inner ear. J. Comp. Neurol. 1998; 393: 320-31.
30. 30. Housley GD, Ashmore JF. Direct measurement of the action of acetylcholine on isolated outer hair cells of the guinea pig cochlea. Proc. R. Soc. Lond. B 1991; 244: 161-7.
31. 31. Housley GD, Ryan AF. Cholinergic and purinergic neurohumoral signalling in the inner ear: A molecular physiological analysis. Audiol. Neuro-Otol 1997; 2: 92-110.
32. 32. Munoz DJ, Thorne PR, Housley GD, Billett TE. Adenosine 5′-triphosphate (ATP) concentrations in the endolymph and perilymph of the guinea-pig cochlea. Hear. Res. 1995; 90: 119-25.
33. 33. Thorne PR, Muñoz DJB, Housley GD, Vlajkovic S, Kendrick IS, Rasam M. Regulation of cochlear sensitivity by extracellular ATP. Proc. Assoc. Res. Otolaryngol. 1999; 22: P482.
34. 34. Vlajkovic SM, Thorne PR, Housley GD, Muñoz DJ, Kendrick IS. Ecto-nucleotidases terminate purinergic signalling in the cochlear endolymphatic compartment. Neuroreport 1998; 9: 1559-65.
35. 35. Vlajkovic SM, Thorne PR, Housley GD, Muñoz DJ, Kendrick IS. The pharmacology and kinetics of ecto-nucleotidases in the perilymphatic compartment of the guinea-pig cochlea. Hear. Res. 1998; 117: 71-80.
36. 36. Mockett BG, Housley GD, Thorne PR. Fluorescence imaging of extracellular purinergic receptor sites and putative ecto-ATPase sites on isolated cochlear hair cells. J. Neurosci. 1994; 14: 6992-7007.
37. 37. White P, Thorne P, Housley G, Mockett B, Billett T, Burnstock G. Quinacrine staining of marginal cells in the stria vascularis of the guinea-pig cochlea: A possible source of extracellular ATP? Hear. Res. 1995; 90: 97-105.
38. 2+-dependent release of ATP from the organ of Corti measured with a luciferin-luciferase bioluminescence assay. Audit. Neurosci. 1996; 2: 187-92.
39. 39. Mountain DC. Electromechanical properties of hair cells. In: Altschuler RA, Hoffman DW, Bobbin RP (eds). Neurobiology of Hearing: The Cochlea. Raven Press, New York. 1986; 77-90.
40. 40. Ashmore JF, Kolston PJ. Hair cell based amplification in the cochlea. Curr. Opin. Neurobiol. 1994; 4: 503-8.
41. 41. Pickles JO, Corey DP. Mechanoelectrical transduction by hair cells. Trends Neurosci. 1992; 15: 254-9.
42. 42. Denk W, Holt JR, Shepherd GMG, Corey DP. Calcium imaging of single stereocilia in hair cells: Localization of transduction channels at both ends of tip links. Neuron 1995; 15: 1311-21.
43. 43. Zheng J, Shen X, He DZZ, Long KB, Madison LD, Dallos P. Prestin is the motor protein at cochlear outer hair cells. Nature 2000; 405: 149-55.
44. 44. Ashmore JF. A fast motile response in guinea-pig outer hair cells: The cellular basis of the cochlear amplifier. J. Physiol. 1987; 388: 323-47.
45. + influx via P2X receptors in cochlear hair cells. Hear. Res. 1998; 119: 1-13.
46. 46. Ashmore JF. The GL Brown Prize Lecture. The cellular machinery of the cochlea. Exp. Physiol. 1994; 79: 113-34.
47. 2+ store to the base of the sensory hair bundle. J. Neurosci. 1999; 19: 6918-29.
48. 48. Schmidt RS, Fernandez C. Development of mammalian endocochlear potential. J. Exp. Zool. 1963; 153: 227-35.
49. + secretion and the transepithelial voltage across marginal cells of stria vascularis in vitro. Hear. Res. 1995; 84: 19-29.
50. 50. Raybould NP, Housley GD. Variation in expression of the outer hair cell P2X receptor conductance along the guinea-pig cochlea. J. Physiol. 1997; 498: 717-27.
51. 51. Munoz DJ, Thorne PR, Housley GD, Billett TE, Battersby JM. Extracellular adenosine 5′-triphosphate (ATP) in the endolymphatic compartment influences cochlear function. Hear. Res. 1995; 90: 106-18.
52. 52. Munoz DJ, Thorne PR, Housley GD. P2X receptor-mediated changes in cochlear potentials arising from exogenous adenosine 5′-triphosphate in endolymph. Hear. Res. 1999; 138: 56-64.
53. 53. Kirk DL, Yates GK. ATP in endolymph enhances electrically-evoked oto-acoustic emissions from the guinea pig cochlea. Neurosci. Lett. 1998; 250: 149-52.
54. 2 receptor subunit of the adenosine 5′-triphosphate-gated ion channel in the adult and developing rat inner ear by in situ hybridization. J. Comp. Neurol. 1998; 393: 403-14.
55. 55. King M, Housley GD, Raybould NP, Greenwood D, Salih SG. Expression of ATP-gated ion channels by Reissner's membrane epithelial cells. Neuroreport 1998; 9: 2467-74.
56. + channel in apical membrane of strial marginal cells. Hear. Res. 1998; 115: 82-92.
57. 57. Liu J, Kozakura K, Marcus DC. Evidence for purinergic receptors in vestibular dark cell and strial marginal cell epithelia of the gerbil. Audit. Neurosci. 1995; 1: 331-40.
58. + secretion in the inner ear. Proc. Assoc. Res. Otolaryngol. 1999; 22: P308.
59. 59. Santos-Sacchi J. Asymmetry in voltage-dependent movements of isolated outer hair cell motility and capacitance. J. Neurosci. 1989; 9: 2954-62.
60. 60. Housley GD, Connor BJ, Raybould NP. Purinergic modulation of outer hair cell electromotility. In: Flock Å, Ottoson D, Ulfendahl M (eds). Active Hearing. Pergamon, Oxford. 1995; 221-38.
61. 2+ signaling in Dieters cells of the guinea-pig cochlea: Active process in supporting cells? In: Flock Å, Ottoson D, Ulfendahl M (eds). Active Hearing. Pergamon, Oxford. 1995; 195-207.
62. 62. Chen C, Bobbin RP. P2X receptors in cochlear Deiters' cells. Br. J. Pharmacol. 1998; 124: 337-44.
63. 63. Kujawa SG, Erostegui C, Fallon M, Crist J, Bobbin RP. Effects of adenosine 5′-triphosphate and related agonists on cochlear function. Hear. Res. 1994; 76: 87-100.
64. 64. Pickles JO. An Introduction to the Physiology of Hearing. Academic Press, London. 1988.
65. 65. Ottersen OP, Takumi Y, Matsubara A, Landsend AS, Laake JH, Usami S. Molecular organization of a type of peripheral glutamate synapse: The afferent synapses of hair cells in the inner ear. Prog. Neurobiol. 1998; 54: 127-48.
66. 66. Robertson D. Horseradish peroxidase injection of physiologically characterized afferent and efferent neurones in the guinea pig spiral ganglion. Hear. Res. 1984; 15: 113-21.
67. 67. Vlajkovic SM, Housley GD, Greenwood D, Thorne PR. Evidence for alternative splicing of ecto-ATPase associated with termination of purinergic transmission. Mol. Brain Res. 1999; 73: 85-92.
68. 2 receptor subunit expression in a subpopulation of cochlear type I spiral ganglion neurones. Neuroreport 1998; 9: 279-82.
69. 69. Salih SG, Housley GD, Raybould NP, Thorne PR. ATP-gated ion channel expression in primary auditory neurones. Neuroreport 1999; 10: 2579-86.
70. 70. Xiang Z, Bo X, Burnstock G. P2X receptor immunoreactivity in the rat cochlea, vestibular ganglion and cochlear nucleus. Hear. Res. 1999; 128: 190-6.
71. 2+ mobilization of type 1 spiral ganglion cells from the guinea pig cochlea. Acta Oto-Laryngol. 1997; 117: 545-52.
72. 72. Munoz DJ, McFie C, Thorne PR. Modulation of cochlear blood flow by extracellular purines. Hear. Res. 1999; 127: 55-61.
73. 73. Ren T, Nuttall AL, Miller JM. ATP-induced cochlear blood flow changes involve the nitric oxide pathway. Hear. Res. 1997; 112: 87-94.
74. 74. Urano T, Nishimori H, Han H et al. Cloning of P2XM, a novel human P2X receptor gene regulated by p53. Cancer Res. 1997; 57: 3281-7.
75. 1 suggests a role for nucleotide signalling in development of the chick embryo. Dev. Dyn. 1999; 214: 152-8.
76. 76. Valera S, Hussy N, Evans RJ et al. A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP. Nature 1994; 371: 516-19.
77. 77. Owens GP, Hahn WE, Cohen JJ. Identification of mRNAs associated with programmed cell death in immature thymocytes. Mol. Cell. Biol. 1991; 11: 4177-88.
78. 2+ responses to acetylcholine and adenosine triphosphate in the otocyst of chick embryo. J. Neurobiol. 1995; 28: 23-34.