A case of high molecular weight insulin-like growth factor-II (IGF-II)- producing hepatoma associated with frequent hypoglycemia and rapid-growth

Kanzo/Acta Hepatologica Japonica

Volumn 41, Issue 5, 2000, Pages 346-351

  Sato, Tsutomu ^a   Kato, Junji ^a   Honma, Hisato ^a   Kura, Toshirou ^a   Ohi, Motoo ^a   Murakami, Ken ^a   Sato, Yasushi ^a   Iyama, Satoshi ^a   Takada, Kouich ^a   Hagiwara, Seiya ^a   Takahashi, Minoru ^a   Sakamaki, Sumio ^a   Niitsu, Yoshiro ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN B;

ARTICLE; CLINICAL FEATURE; DIAGNOSTIC IMAGING; HUMAN; HYPOGLYCEMIA; LIVER CELL CARCINOMA;

EID: 0033921859     PISSN: 04514203     EISSN: None     Source Type: Journal    
DOI: 10.2957/kanzo.41.346     Document Type: Article

References (22)

1. McFadzean AJ, Todd D, Tso SC: Erythrocytosis associated with hepatocellular carcinoma. Blood 29 : 808-811, 1967
2. Oldenburg WA, van-Heerden JA, Sizemore GW, et al: Hypercalcemia and primary hepatic tumors. Arch Surg 117 : 1363-1366, 1882
3. Margolis S, Homcy C: Systemic manifestations of hepatoma. Medicine 51 : 381-391, 1972
4. Wu JC, Daughaday WH, Lee SD, et al: Radioimmunoassay of serum IGF I and IGF-II in patients with chronic liver diseases and hepatocellular carcinoma with or without hypoglycemia. J Lab Clin Med 112 : 589-594, 1988
5. Scott J, Cowell J, Robertson ME, et al: Insulin-like growth factor II gene expression in Wilms' tumor and embryonic tissues. Nature 317 : 260-263, 1985
6. Peres R, Betsholtz C, Westermark B, et al: Frequent expression of growth factors for mesenchymal cells in human mammary carcinoma cell lines. Cancer Res 47 : 3425-3429, 1987
7. Haselbacher GK, Irminger JC, Zapf J, et al: Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level. Proc Natl Acad Sci USA 84 : 1104-1106, 1987
8. Yee D, Cullen KJ, Paik S, et al: Insulin-like growth factor II mRNA expression in human breast cancer. Cancer Res 48 : 6691-6696, 1988
9. Tricoli JV, Rall LB, Karakousis CP, et al: Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas. Cancer Res 46 : 6169-6173, 1986
10. Zapf J, Hauri C, Waldvogel M, et al : Acute metabolic effects and half-lives of intravenously administered insulin-like growth factors I and II in normal and hypophysectomized rats. J Clin Invest 77 : 1768-1775, 1986
11. Shapiro ET, Bell GI, Polonsky KS, et al: Tumor hypoglycemia : Relationship to high molecular weight insulin-like growth factor II. J Clin Invest 85 : 1672-1679, 1990
12. Baxter RC, Daughaday WH : Impaired formation of the ternary insulin-like growth factor-binding protein complex in patients with hypoglycemia due to nonislet cell tumors. J Clin Endocrinol Metab 73 : 696-702, 1991
13. Zapf J, Schoenlc E, Jagars G, et al: Inhibition of the action of non-suppressible insulin-like activity on isolated rat fat cells by binding to its carrier protein. J Clin Invest 63 : 1077-1084, 1979
14. Drop SL, Valiquette G, Guyda HJ, et al: Partial purification and characterization of a binding protein for insulin-like activity (ILAs) in human amniotic fluid : a possible inhibitor of insulin-like activity. Acta Endocrinol (copenh) 90 : 505-518, 1979
15. Meuli C, Zapf J, Froesch ER : NSILA-carrier protein abolishes the action of non-suppressible insulin-like activity (NSILA-S) on perfused rat heart. Diabetologia 14 : 235-259, 1978
16. Rotwein P, Pollock KM, Watson M, et al: Insulin-like growth factor gene expression during rat embryonic development. Endocrinology 121 : 2141-2144, 1987
17. Adams SO, Nissley SP, Greenstein LA, et al: Synthesis of multiplication-stimulating activity (rat insulin-like growth factor II) by rat embryo fibroblasts. Endocrinology 112 : 979-987, 1983
18. Han VK, D'Ercole AJ, Lund PK: Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus. Science 236 : 193-197, 1987
19. Baxter RC: The somatomedins : the insulin-like growth factors. Adv Clin Chem 25 : 49-115, 1986