Clinical trials in palliative care: an ethical evaluation

Patient Education and Counseling

Volumn 41, Issue 1, 2000, Pages 55-62

  Janssens, Rien ^a   Gordijn, Bert ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Autonomy; Beneficence; Human experimentation; Social justice

Indexed keywords

ARTICLE; CLINICAL TRIAL; EVALUATION; EXPERIMENTATION; HUMAN; JUSTICE; MEDICAL CARE; MEDICAL ETHICS; NETHERLANDS; PALLIATIVE THERAPY; PRIORITY JOURNAL; QUALITY OF LIFE;

BIOMEDICAL AND BEHAVIORAL RESEARCH; DEATH AND EUTHANASIA;

BIOETHICS; CLINICAL TRIALS; HUMANS; PALLIATIVE CARE;

EID: 0033921802     PISSN: 07383991     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0738-3991(00)00115-4     Document Type: Article

References (30)

1. Cancer pain relief and palliative care. Technical report series 804. 1990;WHO, Geneva.
2. Rothman D.J. Strangers at the bedside: a history of how law and bioethics transformed medical decision making. 1991;Basic Books, New York.
3. Pappworth M.H. Human guinea pigs. 1967;Routledge, London.
4. Beecher H.K. Ethics in clinical research. N Engl J Med. 274:1966;1354-1360.
5. Zwart H.A.E. Weg met de ethiek? Filosofische beschouwingen over geneeskunde en ethiek. Down with ethics? Philosophical considerations on medicine and ethics :1995;Thesis Publishers, Amsterdam.
6. Saunders C., Summers D., Teller N. Hospice: the living idea. 1981;Edward Arnold, Leeds.
7. Twycross R.G. Choice of strong analgesic in terminal cancer: diamorphine or morphine? Pain. 3:1977;93-104.
8. Saunders C. Hospice care. Am J Med. 65:1978;726-728.
9. Calman K.C., Hanks G.W.C. Clinical and health services research in palliative care. Doyle D., Hanks G.W.C., Macdonald N. Oxford textbook on palliative medicine. 1993;73-77 Oxford University Press, Oxford.
10. Calman K.C., Hanks G.W.C. Clinical and health services research in palliative care. Doyle D., Hanks G.W.C., Macdonald N. The oxford textbook of palliative medicine. 1993;73-77 Oxford University Press, Oxford.
11. Thorpe G. Experiments on the dying. Williams C.J. Introducing new treatments for cancer: practical, ethical and legal problems. 1992;217-225 John Wiley and Sons, Chichester.
12. McQuay H., Moore A. Need for rigorous assessment of palliative care: although difficult, randomised trials are mandatory. Br Med J. 309:1994;1315-1316.
13. McWhinney I.R., Bass M.J., Donner A. Evaluation of a palliative care service: problems and pitfalls. Br Med J. 309:1994;1340-1342.
14. Blackledge G., Lawton F.F. The ethics and practical problems of phase I and II studies. Williams C.J. Introducing new treatments for cancer: practical, ethical and legal problems. 1992;137-148 John Wiley and Sons, Chichester.
15. Calman K.C., Hanks G.W.C. Clinical and health services research in palliative care. Doyle D., Hanks G.W.C., Macdonald N. Oxford textbook of palliative medicine. 1993;73-77 Oxford University Press, Oxford.
16. Holdener E.E., Decoster G., Lim C.M. Ethical aspects of phase I studies in cancer patients. Williams C.J. Introducing new treatments for cancer. Practical, ethical and legal problems. 1992;149-159 John Wiley and Sons, Chichester.
17. Max M.B., Portenoy R.K. Pain research: designing clinical trials in palliative care. Doyle D., Hanks G.W.C., Macdonald N. Oxford textbook on palliative medicine. 1993;77-86 Oxford University Press, Oxford.
18. Skinner B. One patient looks at cancer. Stoll B.A. Coping with cancer stress. 1986;175-185 Nijhoff, Dordrecht.
19. Ricoeur P. Life in quest of narrative. Wood D. On Paul Ricoeur: narratives and interpretation. 1991;Routledge, London.
20. Spaink K. Lichaam is lot - and so what? The body is fate - and so what. Tongeren van P.J.M. Het lot in eigen hand? Destiny in one's own hand :1994;Gooi en Sticht, Baarn.
21. Declaration of Helsinki IV. 1989;World Medical Association, Hong Kong.
22. Katz J. The consent principle of the Nuremberg Code: its significance then and now. Annas G.J., Grodin M.A. The Nazi doctors and the Nuremberg Code: human rights in human experimentation. 1992;227-239 Oxford University Press, Oxford.
23. Welie J.V.M. In the face of suffering: prolegomena to a philosophical foundation of clinical ethics. 1994;Nijmegen University Press, Nijmegen.
24. Janssens M.J.P.A., Zylicz Z., ten Have H.A.M.J. Articulating the concept of palliative care: philosophical and theological perspectives. J Palliat Care. 15:1999;38-44.
25. Welie J.V.M. Authenticity as a foundational principle of medical ethics. Theor Med. 15:1994;211-225.
26. Thorpe G. Experiments on the dying. Williams C.J. Introducing new treatments for cancer: practical, ethical and legal problems. 1992;217-225 John Wiley and Sons, Chichester.
27. Kodish E., Post S.G. Oncology and hope. J Clin Oncol. 13:1995;1817-1822.
28. Zylicz Z., Janssens M.J.P.A. Options in palliative care: dealing with those who want to die. Baillère's Clin Anaesthesiol. 12:1998;121-131.
29. Moltmann J. Theologie der Hoffnung. Untersuchungen zur Begründung und zu den Konsequenzen einer christlichen Eschatologie. Theology of hope. Investigations in the foundations and consequences of a Christian eschatology :1966;Kaiser Verlag, München.
30. Sacred congregation for the doctrine of the faith. Declaration on euthanasia. 1980;Vatican Press, Vatican City.