Polyamines and thiols in the cytoprotective effect of L-cysteine and L-methionine on carbon tetrachloride-induced hepatotoxicity

Amino Acids

Volumn 18, Issue 4, 2000, Pages 319-327

  Chen, W ^a   Kennedy, D O ^a   Kojima, A ^a   Matsui Yuasa, Isao ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

Amino acids; Hepatocytes; L cysteine; L methionine; Polyamines glutathione; Protein sulfhydryl

Indexed keywords

CARBON TETRACHLORIDE; CYSTEINE; GLUTATHIONE; LACTATE DEHYDROGENASE; METHIONINE; POLYAMINE; PUTRESCINE; SPERMIDINE; SPERMINE;

AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME RELEASE; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0033921681     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007260070071     Document Type: Article

References (25)

1. Acuff RV, Smith JT (1983) The influence of cysteine and methionine supplements on polyamine biosynthesis in the rat. J Nutr 113: 2295-2299
2. Bacchi CJ (1981) Content, synthesis and functions of polyamines in trypanosomatids. J Protozol 28: 20-27
3. Bergmeyer HU, Bernt E, Hess B (1965) Lactate dehydrogenase. In: Bergmeyer HU (ed) Methods of enzymatic analysis. Academic Press, New York, pp 736-743
4. Beutler E, Duron O, Kelly BM (1963) Improved method for the determination of blood glutathione. J Lab Clin Med 61: 882-888
5. Burton K (1968) Determinations of DNA concentration with diphenylamine. Methods Enzymol 12B: 163-166
6. Ceconi SC, Bigoli C, Ferrari R, Albertini A, Guarnieri C (1985) Changes in the cardiac glutathione status after ischemia and reperfusion. Experientia 41: 42-43
7. Corti A, Dave C, Williams-Ashman HG, Mihich E, Schenone A (1974) Specific inhibition of the enzymic decarboxylation of S-adenosylmethionine by methylglyoxal bis (guanylhydrazone) and related substances. Biochem J 139: 351-357
8. Deleve LD, Kaplowitz N (1990) Importance and regulation of hepatic glutathione. Semin Liver Dis 10: 251-266
9. Heby O, Persson L (1990) Molecular genetics of polyamine synthesis in eukaryotic cells. Trends Biochem Sci 15: 153-158
10. Higaki I, Matsui-Yuasa I, Terakura M, Kinoshita H, Otani S (1994) Increased spermidine or spermine level is essential for hepatocyte growth factor-induced DNA synthesis in cultured rat hepatocytes. Gastroenterology 106: 1024-1031
11. Ishikawa T, Sies H (1984) Cardiac transport of glutathione disulfide and S-conjugate. Studies with isolated perfused rat heart during hydroperoxide metabolism. J Biol Chem 259: 3838-3843
12. Luk GD (1986) Essential role of polyamine metabolism in hepatic regeneration. Gastroenterology 90: 1261-1267
13. Matsui-Yuasa I, Koike N, Ohtani K, Otani S (1994) Effect of sucrose monostearate, an emulsifier, on polyamine metabolism and phosphatidylinositol turnover in Ehrlich ascites tumor cells. Biochim Biophys Acta 1224: 413-417
14. Meister A (1973) On the enzymology of amino acid transport. Science 180: 33-39
15. Moldeus P, Hogberg J, Orrenius S (1993) Isolation and use of liver cells. Methods Enzymol 51: 60-71
16. Orrenius S (1985) Biochemical mechanisms of cytotoxicity. Trends Pharmacol Sci 6: S15-S20
17. Pegg AE (1988) Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy. Cancer Res 48: 759-774
18. Pösö H, Pegg AE (1982) Effect of a-difluoromethylornithine on polyamine and DNA synthesis in regenerating rat liver. Biochim Biophys Acta 696: 179-186
19. Rigobello MP, Toninello A, Siliprandi D, Bindoli A (1993) Effect of spermine on mitochondrial glulathione release. Biochem Biophys Res Commun 194: 1276-1281
20. Stamler JS, Slivka A (1996) Biological chemistry of thiols in the vasculature and in vascular-related disease. Nutr Rev 54: 1-30
21. Stipanuk MH, Coloso RM, Garcia RAG, Banks MF (1992) Cysteine concentration regulates cysteine metabolism to glutathione, sulfate and taurine in rat hepatocytes. J Nutr 122: 420-427
22. Tabor CW, Tabor H (1984) Polyamines. Ann Rev Biochem 53: 749-790
23. Wang ST, Chen HW, Sheen LY, Lii CK (1997) Methionine and cysteine affect glutathione level, glutathione-related enzyme activities and the expression of glutathione S-transferase isozymes in rat hepatocytes. J Nutr 127: 2135-2141
24. Weis M, Rundgren M, Nelson S, Moldéus P (1996) Peroxidase-catalyzed oxidation of 3,5-dimethyl acetaminophen causes cell death by selective protein thiol modification in isolated rat hepatocytes. Chem Biol Interact 100: 255-265
25. Wu C, Miyagawa C, Kennedy DO, Yano Y, Otani S, Matsui-Yuasa I (1997) Involvement of polyamines in the protection of taurine against the cytotoxicity of hydrazine or carbon tetrachloride in isolated rat hepatocytes. Chem Biol Interact 103: 231-224