An open-label clinical study of nitazoxanide in the treatment of human fascioliasis

Current Therapeutic Research - Clinical and Experimental

Volumn 61, Issue 6, 2000, Pages 339-345

  Kabil, Samir M ^a,c   Ashry, Esmat El ^a   Ashraf, Nassar K ^b  

^a ZAGAZIG UNIVERSITY   (Egypt)

^b US Naval Medical Research Unit No 3 Egypt   (Egypt)

^c NONE   (Egypt)

Author keywords

Fascioliasis; Nitazoxanide; Treatment

Indexed keywords

NITAZOXANIDE;

ABDOMINAL PAIN; ANOREXIA; ARTICLE; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; EGYPT; FASCIOLIASIS; FEVER; HEPATOMEGALY; HUMAN; MAJOR CLINICAL STUDY; NAUSEA; PARASITOSIS; PRIORITY JOURNAL;

EID: 0033921578     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(00)80003-X     Document Type: Article

References (27)

1. 1. Rim HJ, Farag HF, Sornmani S, Cross JH. Food-borne trematodes: Ignored or emerging? Parasitol Today. 1994;10:207-210.
2. 2. Hopkins DR. Homing in on helminthes. Am J Trop Med Hyg. 1992;46:626-634.
3. 3. Mas-Coma S, Bargues MD, Esteban JG. In: Dalton JP, ed. Human Fasciolosis. New York, NY: CABI Publishing; 1999:411-434.
4. 4. Rossignol JF, Cavier R. 2-Benzamido-5-nitrothiazoles. Chem Abstract. 1975;83:28216n.
5. 5. Rossignol JF, Stachulski A. Syntheses and antibacterial activities of tizoxanide an N-(nitrothiazolyl) salicylamide, and its O-aryl glucuronide. J Chem Res (S). 1999;1:44-45.
6. 6. Euzéby J, Prom Tep S, Rossignol JF. Experimentation des proprietes anthelminthiques de la nitazoxanide chez le chien, le chat et les ovins. Rev Med Vet. 1980;131:687-696.
7. 7. Cavier R, Rossignol JF. Etude de diverses associations d'anthelminthiques chez la souris. Rev Med Vet. 1982;133:779-783.
8. 8. Gargala G, Delauney A, Li XD, et al. Efficacy of nitazoxanide, tizoxanide and tizoxanide glucuronide against Cryptosporidium parvum development in sporozoite infected HCT-8 enterocytic cells. J Antimicrob Chemother. In press.
9. 9. Blagburn BL, Drain KL, Land TM, et al. Comparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide and paromomycin against Cryptosporidium parvum infections in a neonatal mouse model. Antimicrob Agents Chemother. 1998;42:2877-2882.
10. 10. Theodos CM, Griffiths JK, D'Onfro J, et al. The efficacy of nitazoxanide against Cryptosporidium parvum in cell culture and in animal models. Antimicrob Agents Chemother. 1998;42:1959-1965.
11. 11. Li XD, Brasseur P, Agnamey P, et al. Long-lasting anticryptosporidial activity of nitazoxanide in an immunosuppressed rat model. Antimicrob Agents Chemother. In press.
12. 12. Didier E, Maddry J, Kwong C, et al. Screening of compounds for antimicrosporidial activity in vitro. Folia Parasitol. 1998;45:129-139.
13. 13. Dubreuil L, Houcke I, Mouton Y, Rossignol JF. In vitro evaluation of activities of nitazoxanide and desacetyl-nitazoxanide against anaerobes and aerobic organisms. Antimicrob Agents Chemother. 1996;40:2266-2270.
14. 14. Mégraud F, Occhialini A, Rossignol JF. Nitazoxanide, a potential drug to eradicate Helicobacter pylori with no cross resistance to metronidazole. Antimicrob Agents Chemother. 1998;42:2836-2840.
15. 15. McVay CS, Rolfe RD. The in vitro and in vivo activities of nitazoxanide against Clostridium difficile. Antimicrob Agents Chemother. In press.
16. 16. Doumbo O, Rossignol JF, Prichard E, et al. Nitazoxanide in the treatment of cryptosporidial diarrhea and other intestinal parasitic infections associated with acquired immunodeficiency syndrome in tropical Africa. Am J Trop Med Hyg. 1997;56:637-639.
17. 17. Rossignol JF, Hidalgo H, Feregrino M, et al. A double-blind placebo controlled study of nitazoxanide in the treatment of cryptosporidial diarrhea in AIDS patients in Mexico. Tran R Soc Trop Med Hyg. 1998;92:663-666.
18. 18. Bicart-Sée A, Massip P, Linas MD, Datry A. Successful treatment with nitazoxanide of Enterocytozoon bieneusi microsporidiosis in a patient with AIDS. Antimicrob Agents Chemother. 2000;44:167-168.
19. 19. Abboud P, Lemée V, Gargala G, et al. Successful treatment of metronidazole-and albendazole-resistant giardiasis with nitazoxanide in a patient with AIDS. Emerg Infect Dis. In press.
20. 20. Romero Cabello R, Robert Guerrero L, Muñoz Garcia MR, Geyne Cruz A. Nitazoxanide for the treatment of intestinal protozoan and helminthic infections in Mexico. Trans R S Trop Med Hyg. 1997;91:701-703.
21. 21. Abaza H, El-Zayadi A, Kabil SM, Rizk H. Nitazoxanide in the treatment of patients with intestinal protozoan and helminthic infections: A report on 546 patients in Egypt. Curr Ther Res. 1998;59:116-121.
22. 22. Rossignol JF, Maisonneuve H. Nitazoxanide in the treatment of Taenia saginata and Hymenolepis nana. Am J Trop Med Hyg. 1984;33:511-512.
23. 23. Oscar Vásquez T, Rubén Alvarez Ch, Napoleón Gonzales S, et al. Diagnóstico y tratamiento de infección por Cyclospora cayetanensis en pacientes pediátricos. Rev Gastroenterol Peru. 1998;18:116-120.
24. 24. Rossignol JF, Abaza H, Friedman H. Successful treatment of heavily infected human fascioliasis with nitazoxanide: A case report. Trans R Soc Trop Med Hyg. 1998;92:103-104.
25. 25. Katz N, Chaves A, Pellegrino J. A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo. 1972;14:397-402.
26. 26. Campbell WC, Rew RS. Chemotherapy of Parasitic Diseases. New York: Plenum Press; 1986:401-425.
27. 27. Apt W, Aguilera X, Vega F, et al. Treatment of human chronic fascioliasis with triclabendazole: Drug efficacy and serologic response. Am J Trop Med Hyg. 1995;52:532-535.