An overview of in vitro/ex vivo assays for preclinical evaluation of immunomodulation

Human and Experimental Toxicology

Volumn 19, Issue 4, 2000, Pages 246-250

  House, R V ^a  

^a Covance Laboratories Inc ^*  (United States)

Author keywords

Immunomodulation; Immunotherapeutic; Immunotoxicology; In vitro models; Rodents

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ASSAY; CONFERENCE PAPER; DOG; EXPERIMENTAL MODEL; HUMAN CELL; IMMUNE FUNCTION TEST; IMMUNOMODULATION; METHODOLOGY; NONHUMAN; PRIMATE; PRIORITY JOURNAL; QUALITY CONTROL; RODENT; SPECIES DIFFERENCE; SWINE;

ANIMALIA; CANIS FAMILIARIS; PRIMATES; RODENTIA; SUS SCROFA;

EID: 0033920994     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/096032700678815800     Document Type: Conference Paper

References (4)

1. Luster MI, Munson AE, Thomas PT, Holsapple MP, Fenters JD, White KL Jr., Lauer LD, Germolec DR, Rosenthal GJ, Dean JH. Development of a testing battery to assess chemical-induced immunotoxicity: National Toxicology Program's guidelines for immunotoxicity evaluation in mice. Fund Appl Toxicol 1988; 10: 2-19.
2. Luster MI, Portier C, Pait DG, White KL Jr., Gennings C, Munson AE, Rosenthal GJ. Risk assessment in immunotoxicology: I. Sensitivity and predictability of immune tests. Fund Appl Toxicol 1992; 18: 200-210.
3. Pastoret P-P, Griebel P, Bazin H, Govaerts A. Handbook of Vertebrate Immunology. Academic Press, San Diego, 1998.
4. Thomas PT, House RV. Preclinical immunotoxicity assessment. In: Derelanko MJ, Hollinger MA(eds.) CRC Handbook of Toxicology, CRC Press, Boca Raton, 1995, pp. 293-316.