Effects of Naturin 2 on colony formation by hematopoietic progenitor cells in human umbilical cord blood mediated by induction of release of growth factors

In Vivo

Volumn 14, Issue 3, 2000, Pages 441-446

  Lu, Li ^a,b,c   Jia, Xiao Qing ^d,e  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WALTHER CANCER INSTITUTE   (United States)

^d Greenland Inc   (United States)

^e Xing Ya Pharmaceutical Co Ltd   (China)

Author keywords

Hematopoietic stem progenitor cells, naturin 2, cytokines

Indexed keywords

BIOLOGICAL RESPONSE MODIFIER; COLONY STIMULATING FACTOR 1; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 3; NATURIN 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; COLONY FORMATION; CYTOKINE RELEASE; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; UMBILICAL CORD BLOOD;

EID: 0033918313     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Shen R-N, Lu L, Hong W-D, Jia X-Q, Wong M-L, Kaiser HE: Naturin: A potent bio-immunomodifier in experimental studies and clinical trials. In Vivo 10: 201-210, 1996.
2. Shen R-N, Lu L, Jia X-Q, Wong M-L, Kaiser HE: The therapeutic effect of Naturin 2 on Lewis lung carcinoma and murine-AIDS. In "Eicosanoids and other cioactive lipids in cancer inflammation and radiation injury", edited by Honn et al. Plenum press, N.Y. pp. 541-549, 1997.
3. Abramson S, Miller RG, Phillips RA: The identification in adult bone marrow of pluripotent and restricted stem cells of the myeloid and lymphoid system. J Exp Med 145: 1567-1579, 1977.
4. Spangrude GJ, Smith L, Uchida N, Ikuta K, Heimfeld S, Friedman J, Weissman IL: Mouse hematopoietic stem cells. Blood 78: 1395-1402, 1991.
5. Lu L, Shen R-N, Broxmeyer HE: Stem cell from bone marrow, umbilical cord blood and peripheral blood for clinical application: current status and future application. CRC Critical Reviews in Hematology/Oncology 22: 61-78, 1996.
6. Dexter TM, Allen TD, Lajtha LG: Conditions controlling the proliferation of haemopoietic stem cells in vitro. J cell Physiol 91: 335-344, 1977.
7. Morrison SJ, Shah NM, Anderson DJ: Regulatory mechanisms in stem cell biology. Cell 88: 287-298, 1997.
8. Broxmeyer HE, Lu L, Gaddy J, Ruggieri L, Srivastava A, Risdon G: Human umbilical cord blood transplantation: The immunology, expansion and therapeutic applications of hematopoietic stem and progenitor cells. In: Hematopoietic Stem cells: Biology and Therapeutic Applications. D.J. Levitt and R. Mertelsmann [eds], New Yord, Basel. Hong Kong, pp. 297-317, 1995.
9. Lu L, Heinrich MC, Wang L-S, Dai M-S, Zigler AJ, Chai L, Broxmeyer HE: Retroviral-mediated gene transduction of c-kit into single hematopoietic progenitor cells from cord blood enhances erythroid colony formation and decreases sensitivity to inhibition by tumor necrosis factor-α and transforming growth factor-β1. Blood 94: 2319-2332, 1999.
10. Lu L, Srour EF, Warren DJ, Walker D, Graham CD, Walker EB, Jansen J, Broxmeyer HE: Enhancement of release of granulocyte-and granulocyte-macrophage colony-stimulating factors from phytohemagglutinin-stimulated sorted subsets of human T lymphocytes by recombinant human tumor necrosis factor-α. Synergism with recombinant human IFN-γ. J Immunol 141: 210-207, 1988.
11. Lu L, Walker D, Graham CD, Waheed A, Shadduck RK, Broxmeyer HE: Enhancement of release from MHC class antigen-positive monocytes of hematopoietic colony stimulating factors CSF-1 and G-CSF by recombinant human tumor necrosis factor-alpha: Synergism with reecombinant human interferon-gamma. Blood 72: 34-41, 1988.