Peripheral and intraamygdalar administration of the dopamine D1 receptor antagonist SCH 23390 blocks fear-potentiated startle but not shock reactivity or the shock sensitization of acoustic startle

Behavioral Neuroscience

Volumn 114, Issue 2, 2000, Pages 262-272

  Greba, Quentin ^a   Kokkinidis, Larry ^a  

^a UNIVERSITY OF CANTERBURY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DOPAMINE 1 RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; AUDITORY STIMULATION; AVERSIVE BEHAVIOR; CONDITIONING; EMOTION; FEAR; LEARNING DISORDER; MALE; NONHUMAN; RAT; SENSITIZATION; SHOCK; STARTLE REFLEX; STIMULUS RESPONSE;

EID: 0033914475     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.114.2.262     Document Type: Article

References (56)

1. Arnt, J. (1982). Pharmacological specificity of conditioned avoidance response inhibition in rats: Inhibition by neuroleptics and correlation to dopamine receptor blockade. Acta Pharmacologica et Toxicologica, 51, 321-329.
2. Aronson, T. A., & Craig, L. (1986). Cocaine precipitation of panic disorder. American Journal of Psychiatry, 143, 643-645.
3. Bijak, M., & Smialowski, A. (1989). Serotonin receptor blocking effect of SCH 23390. Pharmacology, Biochemistry and Behavior, 32, 585-587.
4. Blackburn, J. R., Pfaus, J. G., & Phillips, A. G. (1992). Dopamine functions in appetitive and defensive behaviors. Progress in Neurobiology, 39, 247-279.
5. Borowski, T. B., & Kokkinidis, L. (1994). Cocaine preexposure sensitizes conditioned fear in a potentiated acoustic startle paradigm. Pharmacology, Biochemistry and Behavior, 49, 935-942.
6. Borowski, T. B., & Kokkinidis, L. (1996). Contribution of ventral tegmental area dopamine neurons to expression of conditional fear: Effects of electrical stimulation, excitotoxin lesions, and quinpirole infusion on potentiated startle in rats. Behavioral Neuroscience, 110, 1349-1364.
7. 1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: Implications for psychomotor stimulant psychosis. Behavioral Neuroscience, 112, 952-965.
8. 2 subtypes of dopamine receptors in rat brain. Journal of Neurochemistry, 6, 3177-3188.
9. 1 antagonist SCH 23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat. Brain Research, 692, 47-56.
10. Coco, M. L., Kuhn, C. M., Ely, T. D., & Kilts, C. D. (1992). Selective activation of mesoamygdaloid dopamine neurons by conditioned stress: Attenuation by diazepam. Brain Research, 590, 39-47.
11. Davis, M. (1989). Sensitization of the acoustic startle reflex by footshock. Behavioral Neuroscience, 103, 495-503.
12. Davis, M. (1992). The role of the amygdala in conditioned fear. In J. P. Aggleton (Ed.), The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction (pp. 255-305). New York: Wiley-Liss.
13. Davis, M., Falls, W. A., Campeau, S., & Kim, M. (1993). Fear-potentiated startle: A neural and pharmacological analysis. Behavioural Brain Research, 58, 175-198.
14. 1 dopamine receptor in the rat brain: Quantitative autoradiographic localization using an iodinated ligand. Neuroscience, 26, 83-100.
15. Deutch, A. Y., Tam, S. Y., & Roth, R. H. (1985). Footshock and conditioned stress increase 3,4 dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not the substantia nigra. Brain Research, 333, 143-146.
16. Fanselow, M. S. (1990). Factors governing one-trial contextual conditioning. Animal Learning & Behavior, 18, 264-270.
17. Frey, U., Matthies, H., Reymann, K. G., & Matthies, H. (1991). The effect of dopaminergic D1 receptor blockade during tetanization on the expression of long-term potentiation on the rat CA1 region in vitro. Neuroscience Letters, 129, 111-114.
18. Frey, U., Schroeder, H., & Matthies, H. (1990). Dopaminergic antagonists prevent long-term maintenance of posttetanic LTP in the CA1 region of hippocampal slices. Brain Research, 522, 69-75.
19. Gawin, F. H. (1986). Neuroleptic reduction of cocaine-induced paranoia but not euphoria? Psychopharmacology, 90, 142-143.
20. Gelowitz, D. L., & Kokkinidis, L. (1999). Enhanced amygdala kindling after electrical stimulation of the ventral tegmental area: Implications for fear and anxiety. Journal of Neuroscience, 19, 1-5.
21. Gifkins, A., & Kokkinidis, L. (2000). Direct infusion of quinpirole, muscimol, and flurazepam into the ventral tegmental area block the shock sensitization of acoustic startle: Implications for benzodiazepines and anxiety. Unpublished manuscript.
22. Gordon, M. K., & Rosen, J. B. (1999). Lasting effects of repeated cocaine administration on acoustic and fear-potentiated startle in rats. Psychopharmacology, 144, 1-7.
23. Guarraci, F. A., Frohardt, R. J., & Kapp, B. S. (1999). Amygdaloid D1 receptor involvement in Pavlovian fear conditioning. Brain Research, 827, 28-40.
24. Guarraci, F. A., & Kapp, B. S. (1999). An electrophysiological characterization of ventral tegmental area dopaminergic neurons during differential Pavlovian fear conditioning in the awake rabbit. Behavioural Brain Research, 99, 169-179.
25. Huang, Y.-Y., & Kandel, E. R. (1996). D1/D5 receptors mediate a protein synthesis-dependent late phase of LTP in the amygdala. Society for Neuroscience Abstracts, 22, 332.
26. Ichihara, K., Nabeshima, T., & Kameyama, T. (1989). Differential effects of pimozide and SCH 23390 on acquisition of learning in mice. European Journal of Pharmacology, 164, 189-195.
27. Inoue, T., Hashimoto, S., Tsuchiya, K., Izumi, T., Ohmori, T., & Koyama, T. (1996). Effect of citalopram, a selective serotonin reuptake inhibitor, on the acquisition of conditioned freezing. European Journal of Pharmacology, 311, 1-6.
28. Kalivas, P., & Stewart, J. (1991). Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Research Reviews, 16, 223-244.
29. LeDoux, J. E. (1992). Emotion and the amygdala. In J. P. Aggleton (Ed.), The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction (pp. 339-351). New York: Wiley-Liss.
30. Lee, Y., Walker, D., & Davis, M. (1996). Lack of a temporal gradient of retrograde amnesia following NMDA-induced lesions of the basolateral amygdala assessed with the fear-potentiated startle paradigm. Behavioral Neuroscience, 110, 836-839.
31. Le Moal, M., Cardo, B., & Stinus, L. (1969). Influence of ventral mesencephalic lesions on various spontaneous and conditioned behaviors in the rat. Physiology & Behavior, 4, 567-574.
32. Maren, S., Aharonov, G., & Fanselow, M. S. (1996). Retrograde abolition of conditional fear after excitotoxic lesions in the basolateral amygdala of rats: Absence of a temporal gradient. Behavioral Neuroscience, 110, 718-726.
33. Marshall, J. F., Levitan, D., & Stricker, E. M. (1976). Activation-induced restoration of sensorimotor functions in rats with dopamine-depleting brain lesions. Journal of Comparative and Physiological Psychology 90, 536-546.
34. McNish, K. A., Gewirtz, J. C., & Davis, M. (1997). Evidence of contextual fear after lesions of the hippocampus: A disruption of freezing but not fear-potentiated startle. Journal of Neuroscience, 17, 9353-9360.
35. 2 dopamine receptors mRNAs in rat brain. Neuropsychopharmacology, 5, 231-242.
36. Miserendino, M. J. D., Sananes, C. B., Melia, K. R., & Davis, M. (1990, June 21). Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala. Nature, 345, 716-718.
37. Munro, L. J., & Kokkinidis, L. (1997). Infusion of quinpirole and muscimol into the ventral tegmental area inhibits fear-potentiated startle: Implications for the role of dopamine in fear expression. Brain Research, 746, 231-238.
38. Oades, R. D., & Halliday, G. M. (1987). Ventral tegmental area (A10) system: Neurobiology. 1: Anatomy and connectivity. Brain Research Reviews, 12, 117-165.
39. 5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses. Journal of Neuroscience, 16, 7478-7486.
40. Overton, D. A. (1964). State-dependent or "dissociated" learning produced by pentobarbital. Journal of Comparative and Physiological Psychology, 57, 3-12.
41. Paxinos, G., & Watson, C. (1986). The rat brain in stereotaxic coordinates (2nd ed.). New York: Academic Press.
42. Richardson, R., & Elsayed, H. (1998). Shock sensitization of startle in rats: Role of contextual conditioning. Behavioral Neuroscience, 112, 1136-1141.
43. Rogan, M. T., Staubli, U. V., & LeDoux, J. E. (1997, December 11). Fear conditioning induces associative long-term potentiation in the amygdala. Nature, 390, 604-607.
44. Rosen, J. B., & Davis, M. (1988). Enhancement of acoustic startle by electrical stimulation of the amygdala. Behavioral Neuroscience, 102, 195-202.
45. Rosen, J. B., Hamerman, E., Sitcoske, M., Glowa, J. R., & Schulkin, J. (1996). Hyperexcitability: Exaggerated fear-potentiated startle produced by partial amygdala kindling. Behavioral Neuroscience, 110, 43-50.
46. Salamone, J. D. (1994). The involvement of nucleus accumbens dopamine in appetitive and aversive motivation. Behavioural Brain Research, 61, 117-133.
47. Sanger, D. J. (1987). The actions of SCH 23390, a D-1 receptor antagonist, on operant and avoidance behavior in rats. Pharmacology, Biochemistry and Behavior, 26, 509-513.
48. Stevens, J. R., & Livermore, A. (1978). Kindling of the mesolimbic dopamine system: Animal model of psychosis. Neurology, 28, 36-46.
49. Stevens, J. R., Wilson, K., & Foote, W. (1974). GABA blockade, dopamine and schizophrenia: Experimental studies in the cat. Psychopharmacologia (Berlin), 39, 105-111.
50. Swanson, L. W. (1982). The projections of the ventral tegmental area and adjacent regions: A combined fluorescence retrograde tracer and immunofluorescence study in the rat. Brain Research Bulletin, 9, 321-353.
51. Teyler, T. J., & Discenna, P. (1984). Long-term potentiation as a candidate mnemonic device. Brain Research Reviews, 7, 15-28.
52. Trulson, M. E., & Preussler, D. W. (1984). Dopamine-containing ventral tegmental area neurons in freely moving cats: Activity during sleep-waking cycle and effects of stress. Experimental Neurology, 83, 367-377.
53. 1 receptor antagonist SCH 23390 into the amygdala blocks fear expression in a potentiated startle paradigm. Brain Research, 795, 128-136.
54. Willick, M. L., & Kokkinidis, L. (1995). Cocaine enhances the expression of fear-potentiated startle: Evaluation of state-dependent extinction and the shock-sensitization of acoustic startle. Behavioral Neuroscience, 109, 929-938.
55. Winer, B. J. (1962). Statistical principles in experimental design. New York: McGraw-Hill.
56. Wise, R. A., & Hoffman, D. C. (1992). Localization of drug reward mechanism by intracranial injections. Synapse, 10, 247-263.