Lactic acidosis associated with nucleoside analog therapy in an HIV- positive patient

AIDS Patient Care and STDs

Volumn 14, Issue 7, 2000, Pages 339-342

  Goldfarb Rumyantzev, Alexander S ^a   Jeyakumar, Alwin ^a   Gumpeni, Rammohan ^a   Rubin, David ^a  

^a NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; LAMIVUDINE; NEVIRAPINE; NUCLEOSIDE DERIVATIVE; STAVUDINE;

ADULT; ARTICLE; CASE REPORT; DRUG MECHANISM; DRUG MONITORING; DRUG SAFETY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LACTIC ACIDOSIS; LIVER BIOPSY;

ACIDOSIS, LACTIC; ADULT; ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; DIAGNOSIS, DIFFERENTIAL; FEMALE; HIV INFECTIONS; HUMANS; LAMIVUDINE; NEVIRAPINE; REVERSE TRANSCRIPTASE INHIBITORS; STAVUDINE;

EID: 0033912964     PISSN: 10872914     EISSN: None     Source Type: Journal    
DOI: 10.1089/108729100413194     Document Type: Article

References (12)

1. Medina DJ, Tsai CH, Hsuing GD, Cheng YC. Comparison of mitochondrial morphology, mitochondrial DNA content and cell viability in cultured cells treated with three antiHIV Dideoxynucleosides. Antimicrob Agents Chemother 1994;38:1824-1828.
2. Lenzo NP, Garas BA, French, MA. Hepatic steatosis and lactic acidosis associated with Stavudine treatment in a HIV patient: A case report (Letter). AIDS 1997;11:1294-1296.
3. Coyle T, Abel E. Lactic acidosis and AIDS (Letter; comments). Ann Intern Med 1993;119:344.
4. Crowley VE, Olukogu AO. The chemical pathology of AIDS (Letter; comments). Ann Clin Biochem 1995;32(Pt 5):511-512.
5. Le Bras P, D'Oiron R, Quertainmont Y, Halfon P, Caquet R. Metabolic, hepatic and muscular changes during Zidovudine therapy: A drug induced mitochondrial disease? (Letter). AIDS 1994;8:716-717.
6. Mouly S, Khuong MA, Cabie A, Saimot AG, Coulad JP. Beri-Beri and thiamine deficiency in HIV infection (Letter). AIDS 1996;10:931-932.
7. Baram D, Cooke J. Lactic acidosis and AIDS (Letter, comments). Ann Intern Med 1993;119:345.
8. Fulop M. Lactic acidosis and AIDS (Letter, comments). Ann Intern Med 1993;119:344.
9. Bissuel F, Bruneel F, Habersetzer F et al. Fulminant hepatitis with severe lactic acidosis in HIV-infected patients on didanosine therapy. J Intern Med 1994;235:367-371.
10. Fortgang IS, Belitsos PC, Chaisson RE, Moore RD. Hepatomegaly and steatosis in HIV-infected patients receiving nucleoside analog antiretroviral therapy. Am J Gastroenterol 1995;90:1433-1436.
11. Stein DS. A new syndrome of hepatomegaly and severe steatosis in HIV seropositive patients. AIDS Clin Care 1994;6:19-20.
12. Lewis W, Dalakas, MC. Mitochondrial toxicity of antiviral drugs. Nature Med 1995;1:417-421.