Use of synthetic cardiolipin and lecithin in the antigen used by the Venereal Disease Research Laboratory test for serodiagnosis of syphilis

Clinical and Diagnostic Laboratory Immunology

Volumn 7, Issue 4, 2000, Pages 658-661

  Castro, Arnold R ^a   Morrill, William E ^a   Shaw, Walter A ^b   Gale, David C ^b   Park, Mahin M ^c   Peregrino Ferreira, Luiz A ^d   Bazzo, Maria L ^d   Pope, Victoria ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b Georgia Department of Labor   (United States)

^c Avanti Polar Lipids Inc   (United States)

^d FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN; CHOLESTEROL; PHOSPHATIDYLCHOLINE; REAGINIC ANTIBODY;

ARTICLE; HUMAN; IMMUNOREACTIVITY; PRIORITY JOURNAL; REAGIN TEST; SERODIAGNOSIS; STANDARDIZATION; SYPHILIS; VENEREAL DISEASE REACTION TEST;

CARDIOLIPINS; HUMANS; PHOSPHATIDYLCHOLINES; SENSITIVITY AND SPECIFICITY; SYPHILIS; SYPHILIS SERODIAGNOSIS;

EID: 0033912366     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/CDLI.7.4.658-661.2000     Document Type: Article

References (13)

1. Belisle, J. T., and M. E. Brandt. 1994. Fatty acids of Treponema pallidum and Borrelia burgdorferi lipoproteins. J. Bacteriol. 176:2151-2157.
2. Centers for Disease Control and Prevention. 1998. Guidelines for treatment of sexually transmitted diseases. Morb. Mortal. Wkly. Rep. 47(no. RR-1): 28-47.
3. De Haas, G. H., and L. L. M. Van Deenen. 1965. Chemical structure and serological activity of synthetic and natural cardiolipin. Nature 206:935.
4. Faure, M., and M. J. Coulon-Morelec. 1963. Rapports entre la structure chimique du cardiolipide et son activite serologique. Ann. Inst. Pasteur. 104:246-263.
5. George, R. W., E. F. Hunter, and M. B. Fears. 1998. Fluorescent treponemal antibody-absorption (FTA-ABS) test, p. 225-245. In S. A. Larsen, V. Pope, R. E. Johnson, and E. J. Kennedy, Jr. (ed.), A manual of tests for syphilis, 9th ed. American Public Health Association, Washington, D.C.
6. Inoue, K., and S. Nojima. 1967. Immunochemical studies of phospholipids. Chem. Phys. Lipids. 1:360-367.
7. Kennedy, E. J., Jr., and E. T. Creigton. 1998. Venereal disease research laboratory (VDRL) slide test, p. 157-178. In S. A. Larsen, V. Pope, R, E. Johnson, and E. J. Kennedy, Jr. (ed.), A manual of tests for syphilis, 9th ed. American Public Health Association, Washington, D.C.
8. Larsen, S. A., E. A. Hambie, G. H. Wobig, and E. J. Kennedy. 1985. Cerebrospinal fluid serologic test for syphilis: treponemal and nontreponemal tests, p. 157-162. In R. Morisset and E. Kurstak (ed.), Advances in sexually transmitted diseases. VNU Science Press, Utrecht, The Netherlands.
9. Matthews, H. M., T. K. Yang, and H. M. Jenkin. 1979. Unique lipid composition of Treponema pallidum (Nichols virulent strain). Infect. Immun. 24:713-719.
10. Pangborn, M. C. 1941. A new serologically active phospholipid from beef heart. Proc. Soc. Exp. Biol. Med. 48:484.
11. Reeves, M. W., B. E. McGrew, B. McLaurin, and L. Pine. 1981. Relationship of phospholipid chemistry to serological reactivity in the Venereal Disease Research Laboratory slide test antigen. J. Clin. Microbiol. 14:48-54.
12. Reyn, A. 1956. Use of synthetic, crystalline, dimyristoyl lecithin in cardiolipin antigens. Bull. W. H. O. 14:567-576.
13. Tonks, D. B., and R. H. Allen. 1953. The use of some synthetic phosphatides in antigens for the serodiagnosis of syphilis. Science 118:55-56.