Hyperplastic-like mucosal change in Crohn's disease: Unusual form of dysplasia?

Modern Pathology

Volumn 13, Issue 7, 2000, Pages 797-801

  Kilgore, Sony P ^a   Sigel, Jessica E ^a   Goldblum, John R ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Crohn's disease; Dysplasia; Hyperplasia; p53

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; CANCER RISK; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DYSPLASIA; HUMAN; HUMAN TISSUE; HYPERPLASIA; INTESTINE CARCINOMA; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0033911197     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880138     Document Type: Article

References (23)

1. Choi PM, Zelig MP. Similarity of colorectal cancer in Crohn's disease and ulcerative colitis: implications for carcinogenesis and prevention. Gut 1994;35:950-4.
2. Connell WR, Sheffield JP, Kamm MA, Ritchie JK, Hawley PR, Lennard-Jones JE. Lower gastrointestinal malignancy in Crohn's disease. Gut 1994;35:347-52.
3. Hamilton SR. Colorectal carcinoma in patients with Crohn's disease. Gastroenterology 1985;89:398-407.
4. Ekbom A, Helmick C, Zack M, Adami H-O. Ulcerative colitis and colorectal cancer: a population-based study. N Engl J Med 1990;323:1228-33.
5. Harpaz N, Talbot IC. Colorectal cancer in idiopathic inflammatory bowel disease. Semin Diagn Pathol 1996;13:339-57.
6. Sigel JE, Petras RE, Lashner BA, Fazio VW, Goldblum JR. Intestinal adenocarcinoma in Crohn's disease: a report of 30 cases with a focus on coexisting dysplasia. Am J Surg Pathol 1999;23:651-5.
7. Filipe MI. Value of histochemical reactions for mucosubstances in the diagnosis of certain pathological conditions of the colon and rectum. Gut 1969;10:577-86.
8. Dawson PA, Filipe MI. An ultrastructural and histochemical study of the mucous membrane adjacent to and remote from carcinoma of the colon. Cancer 1976;37:2388-98.
9. Saffos RO, Rhatigan RM. Benign (nonpolypoid) mucosal changes adjacent to carcinomas of the colon: a light microscopic study of 20 cases. Hum Pathol 1977;8:441-9.
10. Filipe MI. The value of a study of the mucosubstances in rectal biopsies from patients with carcinoma of the rectum and lower sigmoid in the diagnosis of premalignant mucosa. J Clin Pathol 1972;25:123-8.
11. Lev R, Grover R. Precursors of human colon cancer: a serial section study of colectomy specimens. Cancer 1981;47:2007-15.
12. Robey-Cafferty SS, Ro JY, Ordonez NG, Cleary KR. Transitional mucosa of colon. A morphological, histochemical and immunohistochemical study. Arch Pathol Lab Med 1990; 114:72-5.
13. Isaacson P, Attwood PRA. Failure to demonstrate specificity of morphological and histochemical changes in mucosa adjacent to colonic carcinoma (transitional mucosa). J Clin Pathol 1979;32:214-8.
14. Listinsky CM, Riddell RH. Patterns of mucin secretion in neoplastic and non-neoplastic diseases of the colon. Hum Pathol 1981;10:923-9.
15. Mori M, Shimono R, Adachi Y, Matsuda H, Kuwano H, Sugimachi K, et al. Transitional mucosa in human colorectal lesions. Dis Colon Rectum 1990;33:498-501.
16. Sawady J, Friedman MI, Katzin WE, Mendelsohn G. Role of the transitional mucosa of the colon in differentiating primary adenocarcinoma from carcinomas metastatic to the colon. An immunohistochemical study. Am J Surg Pathol 1991;15:136-44.
17. Riddell RH, Levin B. Ultrastructure of the "transitional mucosa" adjacent to large bowel carcinoma. Cancer 1977;40: 2509-22.
18. Marcheggiano A, Iannoni C, Palline F, Fieri G, Gallucci M, Caprilli R. Abnormal patterns of colonic mucin secretion after uretero-sigmoidostomy. Hum Pathol 1984;15:647-50.
19. Sunter JP, Higgs MJ, Cowan WK. Mucosal abnormalities at the anastomosis site in patients who have had intestinal resection for colonic cancer. J Clin Pathol 1985;38: 385-9.
20. Franzin G, Scarpa A, Dina R, Novelli P. "Transitional" and hyperplastic-metaplastic mucosa occurring in solitary ulcer of the rectum. Histopathology 1981;5:527-33.
21. Rhatigan RM, Saffos RO. Mucosal hyperplasia in colonic diverticula. Histopathology 1979;3:153-60.
22. Langlois NEI, Park KGM, Keenan RA. Mucosal changes in the large bowel with endometriosis: a possible cause of misdiagnosis of colitis? Hum Pathol 1994;25:1030-4.
23. Connelly JH, Bruner JM, Robey-Cafferty SS, Sahin A. p53 protein expression in transitional mucosa and adenocarcinomas of the colorectum. Mod Pathol 1992;5:537-9.