Peutz-Jeghers syndrome: Is family screening needed?

Pediatric Surgery International

Volumn 16, Issue 5-6, 2000, Pages 437-439

  Baumgartner, G ^a   Neuweiler, J ^b   Herzog, D ^c  

^a Ostschweizer Kinderspital St Gallen   (Switzerland)

^b Institut fur Pathologie   (Switzerland)

^c Ostschweizer Kinderspital St Gallen   (Switzerland)

Author keywords

Intestinal polyposis; Intussusception; Peutz Jeghers syndrome; Therapy

Indexed keywords

ARTICLE; CHILD; CLINICAL ARTICLE; FAMILIAL DISEASE; FEMALE; HAMARTOMA; HISTOLOGY; HUMAN; HUMAN TISSUE; INTESTINE POLYP; INTUSSUSCEPTION; MALE; PEUTZ JEGHERS SYNDROME; PRIORITY JOURNAL; SCREENING; SIBLING;

ADOLESCENT; ADULT; CHILD; COLONOSCOPY; FEMALE; GENETIC SCREENING; HAMARTOMA; HUMANS; INTESTINAL POLYPS; INTUSSUSCEPTION; JEJUNAL DISEASES; MALE; NEEDS ASSESSMENT; PEDIGREE; PEUTZ-JEGHERS SYNDROME;

EID: 0033911124     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003839900296     Document Type: Article

References (12)

1. Aideyan UO, Kao SCS (1994) Gastric adenocarcinoma metastatic to the testes in Peutz-Jeghers syndrome. Pediatr Radiol 24: 496-497
2. Burt RW, Samowitz WS (1988) The adenomatous polyp and the hereditary polyposis syndromes. Gastroenterol Clin North Am 17: 657-678
3. Entius MM, Westerman AM, Giardiello FM, van Velthuysen M-LF, Polak MM, Slebos RJC, Wilson JHP, Hamilton SR, Offerhaus GJA (1997) Peutz-Jeghers polyps, dysplasia, and K-ras codon 12 mutations. Gut 41: 320-322
4. Foley TR, McGarrity TJ, Abt AB (1988) Peutz-Jeghers syndrome: a clinicopathologic survey of the "Harrisburg family" with a 49-year follow-up. Gastroenterology 95: 1535-1540
5. Giardiello FM, Welsh SB, Hamilton SR, Offerhaus GJA, Gittelsohn AM, Booker SV, Krush AJ, Yardley JH, Luk GD (1987) Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med 316: 1511-1514
6. Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G, Warren W, Aminoff M, Hoglund P, Jarvinen H, Kristo P, Pelin K, Ridanpaa M, Salovaara R, Toro T, Bodmer W, Olschwang S, Olsen AS, Stratton MR, de-la Chapelle A, Aaltonen LA (1998) A serine/ threonine kinase gene defect in Peutz-Jeghers syndrome. Nature 391: 184-187
7. Jeghers H, McKusick VA, Katz KH (1949) Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits: a syndrome of diagnostic significance. N Engl J Med 241: 993-1005
8. Keshtgar AS, Losty PD, Lloyd DA, Morris AI, Pierro A (1997) Recent developments in the management of Peutz-Jeghers syndrome in childhood. Eur J Pediatr Surg 7: 367-368
9. Peutz JLA (1921) Very remarkable case of familial polyposis of mucous membrane of intestinal tract and nasopharynx accompanied by peculiar pigmentations of skin and mucous membrane. Ned Maandschr Geneeskd 10: 134-146
10. Rebsdorf-Pedersen I, Hartvigsen A, Fischer-Hansen B, Toftgaard C, Konstantin-Hansen K, Büllow S (1994) Management of Peutz-Jeghers syndrome. Int J Colorect Dis 9: 177-179
11. Spigelman AD, Arese P, Phillips RKS (1995) Polyposis: the Peutz-Jeghers syndrome. Br J Surg 82: 1311-1314
12. Tomlinson IPM, Olschwang S, Abelovitch D, Nakamura Y, Bodmer WF, Thomas G, Markie D (1996) Testing candidate loci on chromosomes 1 and 6 for genetic linkage to Peutz-Jeghers disease. Ann Hum Genet 60: 377-384