Evidence that the lizard helospectin peptides are O-glycosylated

European Journal of Biochemistry

Volumn 267, Issue 14, 2000, Pages 4556-4560

  Vandermeers Piret, Marie Claire ^b   Vandermeers, André ^b   Gourlet, Philippe ^b   Ali, Mohamed H ^b   Waelbroeck, Magali ^b   Robberecht, Patrick ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b NONE

Author keywords

Helospectin; Lizard peptides; O glycosylation; Vasoactive intestinal peptide receptors

Indexed keywords

HELOSPECTIN;

AMINO ACID SEQUENCE; ARTICLE; LIZARD; MASS SPECTROMETRY; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN GLYCOSYLATION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; AMPHIBIAN VENOMS; ANIMALS; CELL MEMBRANE; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLYCOSYLATION; HUMANS; INHIBITORY CONCENTRATION 50; LIZARDS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDES; RATS; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE, TYPE II; RECEPTORS, VASOACTIVE INTESTINAL POLYPEPTIDE, TYPE I; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRYPSIN; VASOACTIVE INTESTINAL PEPTIDE;

HELODERMA HORRIDUM; SQUAMATA;

EID: 0033910857     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01506.x     Document Type: Article

References (26)

1. 1. Raufman, J.P., Jensen, R.T., Sutliff, V.E., Pisano, J.J. & Gardner, J.D. (1982) Actions of Gila monster venom on dispersed acini from guinea pig pancreas. Am. J. Physiol. 242, G470-G474.
2. 2. Parker, D.S., Raufman, J.P., O'Donohue, T.L., Bledsoe, M., Yoshida, H. & Pisano, J.J. (1984) Amino acid sequences of helospectins, new members of the glucagon superfamily, found in Gila monster venom. J. Biol. Chem. 259, 11751-11755.
3. 3. Hoshino, M., Yanaihara, C., Hong, Y.M., Kishida, S., Katsumaru, Y., Vandermeers, A., Vandermeers Piret, M.C., Robberecht, P., Christophe, J. & Yanaihara, N. (1984) Primary structure of helodermin, a VlP-secretin-like peptide isolated from Gila monster venom. FEBS Lett. 178, 233-239.
4. 4. Vandermeers, A., Gourlet, P., Vandermeers Piret, M.C., Cauvin, A., De Neef, P., Rathe, J., Svoboda, M, Robberecht, P. & Christophe. J. (1987) Chemical, immunological and biological properties of peptides like vasoactive-intestinal-peptide and peptide-histidine-isoleucinamide extracted from the venom of two lizards (Heloderma horridum and Heloderma suspectum). Eur. J. Biochem. 164, 321-327.
5. 5. Vandermeers, A., Bounjoua, Y., Vandermeers-Piret, M.-C., Robberecht, P. & Christophe, J. (1992) Helodermin-like immunoreactivity is artefactually increased in bovine brain by the presence of calmodulin. Biomed. Res. 13, 361-366.
6. 6. Pohl, M. & Wank, S.A. (1998) Molecular cloning of the helodermin and exendin-4 cDNAs in the lizard. Relationship to vasoactive intestinal polypeptide/pituitary adenylate cyclase activating polypeptide and glucagon-like peptide 1 and evidence against the existence of mammalian homologues. J. Biol. Chem. 273, 9778-9784.
7. 7. Andrews, P.C., Hines, C.M. & Dixon, J.E. (1980) Characterization of proline endopeptidase from rat brain. Biochemistry 19, 5494-5500.
8. 8. Vandermeers, A., Bounjoua, Y., Vandermeers-Piret, M.C., Gourlet, P., Cauvin, A., Robberecht, P. & Christophe, J. (1988) Helodermin and helospectin-like peptides present in the venom of the lizards Heloderma horridum and Heloderma suspectum. Ann. NY Acad. Sci. 527, 612-616.
9. 9. Gourlet, P., Vandermeers, A., Vertongen, P., Rathe, J., De Neef, P., Cnudde, J., Waelbroeck, M. & Robberecht, P. (1997) Development of high affinity selective VIP1 receptor agonists. Peptides 18, 1539-1545.
10. 10. Juarranz, M.G., Van Rampelbergh, J., Gourlet, P., De Neef, P., Cnudde, J. & Robberecht, P. (1999) Vasoactive intestinal polypeptide VPAC1 and VPAC2 receptor chimeras identify domains responsible for the specificity of ligand binding and activation. Eur. J. Biochem. 265. 449-456.
11. 11. Eng, I., Andrews, P.C., Kleinman, W.A., Singh, L. & Raufman, J.P. (1990) Purification and structure of exendin-3, a new pancreatic secretagogue isolated from Heloderma harridum venom. J. Biol. Chem. 265, 20259-20262.
12. 12. Eng, J., Kleinman, W.A., Singh, L., Singh, G. & Raufman, J.P. (1992) Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J. Biol. Chem. 267, 7402-7405.
13. 13. Robberecht, P., Waelbroeck, M., De Neef, P., Tastenoy, M., Gourlet, P., Cogniaux, J. & Christophe, J. (1988) A new type of functional VIP receptor has an affinity for helodermin in human SUP-T1 lymphoblasts. FEBS Lett. 228, 351-355.
14. 14. Lutz, E.M., Sheward, W.J., West, K.M., Morrow, J.A., Fink, G. & Harmar, A.J. (1993) The VIP2 receptor: molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide. FEBS Lett. 334, 3-8.
15. 15. Svoboda, M., Tastenoy, M., Van Rampelbergh, J., Goossens, J.F., De Neef, P., Waelbroeck, M. & Robberecht, P. (1994) Molecular cloning and functional characterization of a human VIP receptor from SUP-T1 lymphoblasts. Biochem. Biophys. Res. Commun. 205, 1617-1624.
16. 16. Harmar, A.J., Arimura, A., Gozes, I., Journot, L., Laburthe, M., Pisegna, J.R., Rawlings, S.R., Robberecht, P., Said, S.I., Sreedharan, S.P., Wank, S.A. & Waschek, J.A. (1998) International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactivc intestinal peptide and pituitary adenylate cyclase-activating poly-peptide. Pharmacol. Rev. 50, 265-270.
17. 17. Naruse, S., Yasui, A., Kishida, S., Kadowaki, M., Hoshino, M., Ozaki, T., Robberecht, P., Christophe, J., Yanaihara, C. & Yanaihara, N. (1986) Helodermin has a VIP-like effect upon canine blood flow. Peptides 7, 237-240.
18. 18. Couvineau, A., Rouyer Fessard, C., Maoret, J.J., Gaudin, P., Nicole, P. & Laburthe, M. (1996) Vasoactive intestinal peptide (VIP) 1 receptor. Three nonadjacent amino acids are responsible for species selectivity with respect to recognition of peptide histidine isoleucineamide. J. Biol Chem. 271, 12795-12800.
19. 19. Gooley, A.A. & Williams, K.L. (1997) How to find, identify and quantitate the sugars on proteins. Nature 385, 557-559.
20. 20. Hansen, J.E., Lund, O., Engelbrecht, J., Bohr, H., Nielsen, J.O. & Hansen, J.E. (1995) Prediction of O-glycosylation of mammalian proteins: specificity patterns of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase. Biochem. J. 308, 801-813.
21. 21. Hansen, J.E., Lund, O., Rapacki, K. & Brunak, S. (1997) O-GLYCBASE, Version 2.0: a revised database of O-glycosylated proteins. Nucl Acids Res. 25, 278-282.
22. 22. Hansen, J.E., Lund, O., Tolstrup, N., Gooley, A.A., Williams, K.L. & Brunak, S. (1998) NetOglyc: prediction of mucin type O-glycosylation sites based on sequence context and surface accessibility. Glycoconj. J. 5, 115-130.
23. 23. Gibson, B.W. & Cohen, P. (1990) Liquid secondary ion mass spectrometry of phosphorylated and sulfated peptides and proteins. Methods Enzymol. 193, 480-501.
24. 24. Van den Steen, P., Rudd, P.M., Dwek, R.A. & Opdenakker, G. (1998) Concepts and principles of O-linked glycosylation and principles of O-linked glycosylation. Crit. Rev. Biochem. Mol. Biol. 33, 51-208.
25. 25. Robberecht, P., Yanaihara, N., Yanaihara, C., De Neef, P., Camus, J.C., Vandermeers, A., Vandermeers Piret, M.C. & Christophe, J. (1986) Interaction of synthetic N-and C-terminal fragments of helodermin with rat liver VIP receptors. Peptides 7, 79-82.
26. 26. Meurer, J.A., Colca, J.R., Burton, P.S. & Elhammer, A.P. (1999) Properties of native and in vitro glycosylated forms of the glucagon-like peptide-1 receptor antagonist exendin (9-39). Metabolism 48, 716-724.