Cloning of the mouse desmoglein 3 gene (Dsg3): Interspecies conservation within the cadherin superfamily

Experimental Dermatology

Volumn 9, Issue 4, 2000, Pages 229-239

  Ishikawa, H ^a,b   Li, K ^a   Tamai, K ^b   Sawamura, D ^b   Uitto, Jouni ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b HIROSAKI UNIVERSITY   (Japan)

Author keywords

Bullous diseases; Cell cell adhesion; Epidermal differentiation

Indexed keywords

CADHERIN; COMPLEMENTARY DNA; DESMOGLEIN;

ARTICLE; BULLOUS SKIN DISEASE; CELL ADHESION; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE; GENE STRUCTURE; GENETIC CONSERVATION; KERATINOCYTE; MOLECULAR CLONING; MOUSE; NONHUMAN;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CADHERINS; CATTLE; CHICKENS; CLONING, MOLECULAR; CONSERVED SEQUENCE; DESMOGLEIN 3; DNA PRIMERS; DNA, COMPLEMENTARY; EXONS; HUMANS; INTRONS; KERATINOCYTES; MICE; MOLECULAR SEQUENCE DATA; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC;

EID: 0033909435     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0625.2000.009004229.x     Document Type: Article

References (27)

1. Garrod D R. Desmosomes and hemidesmosomes. Curr Opin Cell Biol 1993: 5: 30-40.
2. Green K J, Jones J C R. Desmosomes and hemidesmosomes: structure and function of molecular components. FASEB 1996: J 10: 871-881.
3. Buxton R S, Cowin P, Franke W W et al. Nomenclature of the desmosomal cadherins. J Cell Biol 1993: 121: 481-483.
4. Amagai M, Klaus-Kovtun V, Stanley J R. Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion. Cell 1991: 67: 869-877.
5. Amagai M, Karpati S, Prussick R, Klaus-Kovtun V, Stanley J R. Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic. J Clin Invest 1992: 90: 919-926.
6. Stanley J R. Cell adhesion molecules as targets of autoantibodies in pemphigus and pemphigoid, bullous diseases due to defective epidermal cell adhesion. Adv Immunol 1993: 53: 291-325.
7. Hashimoto T, Ogawa M M, Konohana A, Nishikawa T. Detection of pemphigus vulgaris and pemphigus foliaceus antigens by immunoblot analysis using different antigen sources. J Invest Dermatol 1990: 94: 327-331.
8. Wolff K, Schreiner E. Ultrastructural localization of pemphigus auto-antibodies within the epidermis. Nature (London) 1971: 229: 59-60.
9. Beutner E H, Chorzelski T P, Jablonska S. Clinical significance of immunofluorescence tests of sera and skin in bullous diseases: A cooperative study. In: Beutner E H, Chorzelski T P, Kumar V, eds. Immunopathology of the Skin. 3rd edn, New York: John Wiley & Sons, 1987: 177-205.
10. Ishikawa H, Silos S A, Tamai K et al. cDNA cloning and chromosomal assignment of the mouse gene for desmoglein 3 (Dsg3), the pemphigus vulgaris antigen. Mamm Genome 1994: 5: 803-804.
11. Buxton R S, Wheeler G N, Pidsley S C et al. Mouse desmocollin (Dsg3) and desmoglein (Dsg1) genes are closely linked in the proximal region of chromosome 18. Genomics 1994: 21: 510-516.
12. Arnemann J, Spurr N K, Buxton R S. The human gene (DSG3) coding for the pemphigus vulgaris antigen is, like the genes coding for the other two known desmogleins, assigned to chromosome 18. Hum Genet 1992: 89: 347-350.
13. Wang Y, Amagai M, Minoshima S et al. The human genes for the desmogleins (DSG1 and DSG3) are located in a small region on chromosome 18q12. Genomics 1994: 20: 492-495.
14. Sanger F, Nicklen S, Coulson A R. DNA sequencing with chain-termination inhibitors. Proc Natl Acad Sci U S A 1977: 74: 5463-5467.
15. Sambrook J, Fritsch E F, Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd edn. New York: Cold Spring Harbor Laboratory, 1989.
16. Ozawa M, Kemler R. Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin. J Cell Biol 1990: 111: 1645-1650.
17. Ringwald M, Baribault H, Schmidt C, Kemler R. The structure of the gene coding for the mouse cell adhesion molecule uvomorulin. Nucl Acids Res 1991: 19: 6533-6539.
18. Hart G W, Brew K, Grant G A, Bradshaw R A, Lennarz W J. Primary structural requirements for the enzymatic formation of the N-glycosidic bond in glycoproteins. J Biol Chem 1979: 254: 9747-9753.
19. Blaschuk O W, Sullivan R, David S, Pouliot Y. Identification of a cadherin cell adhesion recognition sequence. Dev Biol 1990: 139: 227-229.
20. Tamai K, Sawamura D, Do H C, Li K, Uitto J. The human 230-kDa bullous pemphigoid antigen gene (BPAG1): exon-intron organization and identification of regulatory cis-elements in the promoter region. J Clin Invest 1993: 92: 814-822.
21. Silos S A, Tamai K, Li K et al. Cloning of the gene for human pemphigus vulgaris antigen (Desmoglein 3), a desmosomal cadherin. J Biol Chem 1996: 271: 17504-17511.
22. Takeichi M. Cadherins: a molecular family important in selective cell-cell adhesion. Annu Rev Biochem 1990: 59: 237-252.
23. Takeichi M. Cadherin cell adhesion receptors as a morpho-genetic regulator. Science 1991: 251: 1451-1455.
24. Koch P J, Mahoney M G, Ishikawa H et al. Targeted disruption of the pemphigus vulgaris antigen (Desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris. J Cell Biol 1997: 137: 1091-1102.
25. Beutner E H, Jordon R E, Chorzelski T P. The immunopathology of pemphigus and bullous pemphigoid. J Invest Dermatol 1968: 51: 63-80.
26. Stanley J R, Yaar M, Hawley-Nelson P, Katz S. Pemphigus antibodies identify a cell surface glycoprotein synthesized by human and mouse keratinocytes. J Clin Invest 1982: 70: 281-288.
27. Nilles L A, Parry D A D, Powers E E, Angst B D, Wagner R M, Green K J. Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome. J Cell Sci 1991: 99: 809-821.