Growth hormone, insulin-like growth factor I and the CNS: Localization, function and mechanism of action

Growth Hormone and IGF Research

Volumn 10, Issue SUPPL. B, 2000, Pages

  Lobiezz, P E ^a   Zhu, T ^a   Graichen, R ^a   Goh, E L K ^a  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

CNS; Growth hormone; Insulin like growth factor I; Signal transduction

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE BINDING PROTEIN; GROWTH HORMONE RECEPTOR; SOMATOMEDIN C;

CELL FUNCTION; CENTRAL NERVOUS SYSTEM; COGNITION; GENE CONTROL; GENE EXPRESSION; HORMONE ACTION; HORMONE BINDING; HORMONE RELEASE; HUMAN; ONTOGENY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION;

EID: 0033901485     PISSN: 10966374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1096-6374(00)80010-6     Document Type: Review

References (57)

1. Localization and ontogeny of growth hormone receptor gene expression in the central nervous system
2. Prenatal expression of the growth hormone (GH) receptor/binding protein in the rat: A role for GH in embryonic and fetal development?
3. Cellular localization of the growth hormone binding protein in the rat
4. Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalamic somatostatin neurons
5. Hypothalamic GH receptor gene expression in the rat: Effects of altered GH status
6. Growth hormone and its receptors in the central nervous system: Location and functional significance
7. Aging effects on growth hormone receptor binding in the brain
8. Regulation of rat growth hormone receptor gene expression
9. Differential regulation of the growth hormone receptor gene: Effects of dexamethasone and estradiol
10. Expression and distribution of messenger ribonucleic acids for growth hormone (GH) receptor and GH-binding protein in mice during pregnancy
11. Studies on the accessibility of prolactin and growth hormone to brain: Effect of opiate agonists on hormone levels in serial, simultaneous plasma and cerebrospinal fluid samples in the rhesus monkey
12. Growth hormone (GH) immunoreactivity in the rodent and primate CNS: Distribution, characterization and presence posthypophysectomy
13. 125I-labelled human growth hormone in adrenals and other organs of immature hypophysectomized rats
14. 125I-labeled rat growth hormone in regional brain areas and peripheral tissue of the rat
15. Effects of growth hormone and insulin-like growth factors on the central nervous system
16. Treatment of growth hormone-deficient adults with recombinant human growth hormone increases the concentration of growth hormone in the cerebrospinal fluid and affects neurotransmitters
17. A receptor-mediated mechanism for the transport of prolactin from blood to cerebrospinal fluid
18. Regulation of insulin-like growth factor I (IGF-I) gene expression in brain of transgenic mice expressing an IGF-I-luciferase fusion gene
19. Alterations in the neural growth hormone axis following hypoxic-ischemic brain injury
20. In situ hybridization to rat brain and pituitary gland of growth hormone cDNA
21. Growth hormone (GH), thyroid-stimulating hormone (TSH), and luteinizing hormone (LH)-like peptides in the rodent brain: Non-parallel ontogenetic development with pituitary counterparts
22. Impact of endocrine manipulations on brain-based rat growth hormone
23. Developing oligodendroglia express mRNA for insulin-like growth factor-I, a regulator of oligodendrocyte development
24. Expression of IGF-I mRNA in the murine subventricular zone during postnatal development
25. Insulin-like growth factor-I and central nervous system development
26. Growth hormone dependence of somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II messenger ribonucleic acids
27. Hormonal regulation of rat hypothalamic neuropeptide mRNAs: Effect of hypophysectomy and hormone replacement on growth-hormone-releasing factor, somatostatin and the insulin-like growth factors
28. Effects of growth hormone on cerebral development: Morphological studies
29. Restoration of microcephalic cerebrum with hypomyelination in the growth hormone-deficient mouse (lit): Stimulatory effects of GH restricted to the first 20 days of postnatal life
30. Epidermal growth factor and bovine growth hormone stimulate differentiation and myelination of brain cell aggregates in culture
31. Evidence for thyroxine-growth hormone interaction during brain development
32. Effects of insulin on cultured rat brain cells: Stimulation of ornithine decarboxylase activity
33. Stimulation of the proliferation of cortical neurons by prenatal treatment with growth hormone
34. Stimulatory effects of exogenous thyroid hormone and growth hormone on sn-glycerol-3-phosphate dehydrogenase activity in the genetic-hypothyroid mutant mouse cerebellum: Restricted to the second 20 days of postnatal life
35. Effects of growth hormone on brain biogenic amine levels
36. Growth hormone regulates AT-1a angiotensin receptors in astrocytes
37. Modulation of long-term memory and extinction responses induced by growth hormone (GH) and growth hormone releasing hormone (GHRH) in rats
38. Effects of bovine growth hormone on the retarded cerebral development induced by neonatal hydrocortisone intoxication
39. Growth hormone is secreted by ectopic pituitary grafts and stimulates maternal behavior in rats
40. The effect of growth hormone administration on human sleep: A dose-response study
41. Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) expression to hypothalamic GH-releasing factor neurons
42. Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons
43. Growth hormone, insulin-like growth factor I, and motoneuron size
44. Signal transduction through the growth hormone receptor
45. Signaling via JAK tyrosine kinases: Growth hormone receptor as a model system
46. Growth hormone stimulates phosphorylation and activation of elk-1 and expression of c-fos, egr-1, and junB through activation of extracellular signal-regulated kinases 1 and 2
47. JAK2 dependent activation of p38 MAP kinase by growth hormone: Resultant transcriptional activation of ATF-2 and CHOP, cytoskeletal re-organization and mitogenesis
48. Growth hormone stimulates the formation of a multiprotein signaling complex involving p130(Cas) and Crkll. Resultant activation of c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK)
49. Termination of growth hormone pulse-induced STAT5b signaling
50. Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling
51. A kinase to remember: Dual roles for MAP kinase in long-term memory
52. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
53. Mode of action of pituitary growth hormone on target cells
54. Insulin-like growth factor-I receptor signal transduction: At the interface between physiology and cell biology
55. Growth hormone-induced reorganization of the actin cytoskeleton is not required for STAT5 (signal transducer and activator of transcription-5)-mediated transcription
56. Autocrine stimulation of human mammary carcinoma cell proliferation by human growth hormone
57. Crk II participation in the cellular effects of growth hormone and insulin-like growth factor-I: Phosphatidylinositol-3 kinase-dependent and independent effects