Expression of an intestine-specific transcription factor (CDX1) in intestinal metaplasia and in subsequently developed intestinal type of cholangiocarcinoma in rat liver

American Journal of Pathology

Volumn 156, Issue 2, 2000, Pages 621-627

  Ren, Ping ^a   Silberg, Debra G ^b   Sirica, Alphonse E ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT CARCINOMA; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMEOBOX; INTESTINE METAPLASIA; LIVER FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0033894544     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64766-9     Document Type: Article

References (32)

1. Significance of intestinal metaplasia for the evolution of cancer in the biliary tract
2. Intestinal-type adenocarcinoma of the gallbladder: A clinicopathologic and immunocytochemical study of seven cases
3. Mucosal dysplasia of gallbladder: Isolated and adjacent lesions to carcinoma
4. Metaplasia and precursor lesions of gallbladder carcinoma-frequency, distribution, and probability of detection in routine histologic samples
5. Small cell carcinoma of the gallbladder with intestinal metaplastic epithelium
6. Cholangiocarcinoma induced by feeding 3'-methyl-4-dimethylaminoazobenzene to rats
7. 'Intestinal-type' of adenocarcinoma preferentially induced in right/caudate liver lobes of rats treated with furan
8. Cholangiocarcinogenesis and biliary adaptation responses in hepatic injury
9. Intestinal metaplasia and altered enzyme expression in propylnitrosamine-induced Syrian hamster cholangiocellular and gallbladder lesions
10. Metaplastic lesions in intrahepatic bile ducts in hepatolithiasis: A histochemical and immunohisto-chemical study
11. Histochemical and immunohistochemical studies on development of biliary carcinoma in 47 patients with choledochal cyst-special reference to intestinal metaplasia in the biliary tract
12. Intestinal metaplasia as a common option of oval cells in relation to cholangiofibrosis in liver of rats exposed to 2-acetylaminofluorene
13. Bile duct and peribiliary gland responses in fluke-associated cholangiocarcinoma
14. Carcinoma of the gallbladder: The correlation between histogenesis and prognosis
15. Relation of histopathological features to prognosis of gallbladder cancer
16. A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine
17. CDX1 protein expression in normal, metaplastic, and neoplastic human alimentary tract epithelium
18. Isolation, characterization, and precise physical localization of human CDX1, a caudal-type homeobox gene
19. Phenotypic characterization of metaplastic intestinal glands and ductular hepatocytes in cholangiofibrotic esions rapidly induced in the caudate liver lobe of rats treated with furan
20. Sequential appearance of intestinal mucosal cell types in the right and caudate liver lobes of furan-treated rats
21. NEU overexpression in the furan rat model of cholangiocarcinogenesis compared with biliary ductal cell hyperplasia
22. Overexpression of c-Neu and c-Met during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma
23. A unique rat model of bile ductular hyperplasia in which liver is almost totally replaced with well-differentiated bile ductules
24. Biliary proliferation and adaptation in furan-induced rat liver injury and carcinogenesis
25. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures
26. A new rat bile ductular epithelial cell culture model characterized by the appearance of polarized bile ducts in vitro
27. A caudal-type homeobox gene activity associated with the development, and regeneration of the liver
28. Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation
29. An intestine-specific homeobox gene regulates proliferation and differentiation
30. Young GP James RJ: Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma
31. Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox: Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesis
32. Establishment of a novel rat cholangiocarcinoma cell culture model