Intravenous pretreatment with magnolol protects myocardium against stunning

Planta Medica

Volumn 66, Issue 6, 2000, Pages 516-520

  Huang, C H ^a,c   Hong, C Y ^a,c   Tsai, S K ^b,c   Lai, S T ^a   Weng, Z C ^a   Chih, C L ^a   Hsieh, Y H ^a  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Coronary artery occlusion; Magnolol; Myocardial protection; Myocardial stunning

Indexed keywords

MAGNOLOL;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; HEART INFARCTION; HEART INFARCTION SIZE; HEART PROTECTION; MALE; NONHUMAN; PHYTOTHERAPY; RABBIT; STUNNED HEART MUSCLE;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; ANTIOXIDANTS; ARRHYTHMIA; BIPHENYL COMPOUNDS; HEART; INFUSIONS, INTRAVENOUS; LIGNANS; MALE; MYOCARDIAL STUNNING; RABBITS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0033885171     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-8653     Document Type: Article

References (14)

1. Magnolol and honokiol isolated from Magnolia officinalis protect rat heart mitochondria against lipid peroxidation
2. Magnolol protects human sperm motility against lipid peroxidation: A sperm head fixation method
3. Magnolol reduces infarct size and suppresses ventricular arrhythmia in rats subjected to coronary ligation
4. Mechanism of myocardial 'stunning'
5. Beneficial effects of MDL 74,405, a cardioselective water soluble alpha tocopherol analogue, on the recovery of function of stunned myocardium in intact dogs
6. Effect of the hydrophilic alpha-tocopherol analog MDL 74,405 on detection of hydroxyl radicals in stunned myocardium in dogs
7. Time course and determinants of recovery of function after reversible ischemia in conscious dogs
8. The Lambeth Conventions: Guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion
9. Demonstration of free radical generation in 'stunned' myocardium of intact dogs with the use of the spin trap alpha-phenyl-N-tert-butyInitrone
10. Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial 'stunning' is a manifestation of reperfusion injury
11. Direct measurement of myocardial free radical generatioa in an in vivo model: Effects of postischemic reperfusion and treatment with human recombinant superoxide dismutase
12. Superoxide dismutase plus catalase improve contractile function in the canine model of the 'stunned myocardium'
13. Protection against postischemic myocardial dysfunction in anesthetized rabbits with scavengers of oxygen-derived free radicals: Superoxide dismutase plus catalase, N-2-mercaptopropionyl glycine and captopril
14. Protection from oxygen-induced seizures by clonazepam and propylene glycol