Anticonvulsant effect and neurotransmitter modulation of focal and systemic 2-chloroadenosine against the development of pilocarpine-induced seizures

Neuropharmacology

Volumn 39, Issue 12, 2000, Pages 2418-2432

  Khan, Ghous M ^a   Smolders, Ilse ^a   Ebinger, Guy ^a   Michotte, Yvette ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

2 Chloroadenosine; Dopamine; GABA; Glutamate; Pilocarpine induced seizures; SCH 58261

Indexed keywords

2 CHLOROADENOSINE; 4 AMINOBUTYRIC ACID; 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; DOPAMINE; GLUTAMIC ACID; PILOCARPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; DRUG MECHANISM; HIPPOCAMPUS; MALE; MICRODIALYSIS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE;

2-CHLOROADENOSINE; ANIMALS; ANTICONVULSANTS; BEHAVIOR, ANIMAL; ELECTROENCEPHALOGRAPHY; ELECTROPHYSIOLOGY; HIPPOCAMPUS; INJECTIONS; MALE; MUSCARINIC AGONISTS; NEUROTRANSMITTER AGENTS; PILOCARPINE; PYRIMIDINES; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P1; SEIZURES; TRIAZOLES;

EID: 0033884330     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00072-1     Document Type: Article

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