Regulation of host cell translation by viruses and effects on cell function

Current Opinion in Microbiology

Volumn 3, Issue 4, 2000, Pages 366-370

  Thompson, Sunnie R ^a   Sarnow, Peter ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; INITIATION FACTOR; MATRIX PROTEIN; PROTEIN KINASE; VIRUS PROTEIN; VIRUS RNA;

CELL FUNCTION; ENZYME INHIBITION; EUKARYOTIC CELL; HEPATITIS C VIRUS; HERPES VIRUS; HOST CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; POLIOMYELITIS VIRUS; PROTEIN DEGRADATION; REVIEW; TRANSLATION REGULATION; VIRUS CELL INTERACTION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

EID: 0033884066     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(00)00106-5     Document Type: Review

References (36)

1. The scanning model for translation: An update
2. The pathway and mechanism of eukaryotic protein synthesis
3. Internal initiation of translation in eukaryotes: The picornavirus paradigm and beyond
4. Initiation of translation by picornavirus RNAs
5. Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000 dalton polypeotide associated with eucaryotic initiation facor 3 and a cap binding protein complex
6. Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus
7. A novel functional human eukaryotic translation initiation factor 4G
8. A common function for mRNA 5' and 3' ends in translation initiation in yeast
9. Translation initiation factors elF-iso4G and elF-4B interact with the poly(A)-binding protein and increase its RNA binding activity
10. Association of the yeast poly(A) tail binding protein with translation initiation factor elF-4G
11. A newly identified N-terminal amino acid sequence of human elF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation
12. Cleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro
13. Cleavage of poly(A)-binding protein by coxsackievirus 2A protease in vitro and in vivo: Another mechanism for host protein synthesis shutoff?
14. Proteolysis of human eukaryotic translation initiation factor elF4GII, but not elF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection
15. Eukaryotic initiation factor 4GII (elF4GII), but not elF4GI, cleavage correlates with inhibition of host cell protein synthesis after human rhinovirus infection
16. Rotavirus RNA-binding protein NSP3 interacts with elF4GI and evicts the poly(A) binding protein from elF4F
17. Cleavage of eukaryotic translation initiation factor 4G by exogenously added hybrid proteins containing poliovirus 2Apro in HeLa cells: Effects on gene expression
18. Identification of eukaryotic mRNAs that are translated at reduced cap binding complex elF4F concentrations using a cDNA microarray
19. Resistance of ribosomal protein mRNA translation to protein synthesis shutoff induced by poliovirus
20. Cellular internal ribosome entry site (IRES) elements and the use of cDNA microarrays in their investigation
21. Interactions between viruses and the cellular machinery for protein synthesis
22. Isolation of a cDNA clone derived from a blood-borne non-A; non-B viral-hepatitis genome
23. Hepatitis C
24. Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: Molecular mechanisms of kinase regulation
25. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
26. Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein
27. Hepatitis C virus, the E2 envelope protein, and α-interferon resistance
28. Hepatitis-C and hepatocellular-carcinoma
29. Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor elF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of herpes simplex virus 1
30. The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase
31. Cellular elongation factor 1 delta is modified in cells infected with representative alpha-, beta-, or gammaherpesviruses
32. Interaction of the second coding exon of Tat with human EF-1 delta delineates a mechanism for HIV-1-mediated shut-off of host mRNA translation
33. Human immunodeficiency virus type 1 matrix protein interacts with cellular protein HO3
34. Translation elongation factor 1-alpha interacts specifically with the human immunodeficiency virus type 1 Gag polyprotein
35. Cloning and characterization of hlF2, a human homologue of bacterial translation initiation factor 2, and its interaction with HIV-1 matrix
36. Synthesis of murine leukemia virus proteins associated with virions assembled in actinomycin D-treated cells: Evidence for persistence of viral messenger RNA