C-nucleoside analogues of furanfurin as ligands to A1 adenosine receptors

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 9, 2000, Pages 2367-2373

  Franchetti, Palmarisa ^a   Cappellacci, Loredana ^a   Marchetti, Stefano ^a   Martini, Claudia ^b   Costa, Barbara ^b   Varani, Katia ^c   Borea, Pier Andrea ^c   Grifantini, Mario ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

^b Dipartmento di Biologia   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 6 N CYCLOPENTYLADENOSINE; ADENOSINE A1 RECEPTOR; ANTINEOPLASTIC AGENT; C NUCLEOSIDE; CYCLIC AMP; CYCLOHEXYLADENOSINE; INOSINATE DEHYDROGENASE; TIAZOFURIN;

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; CATTLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; RAT; STRIATE CORTEX; STRUCTURE ACTIVITY RELATION; THROMBOCYTE;

ADENYLATE CYCLASE; ADIPOCYTES; ANIMALS; ANTINEOPLASTIC AGENTS; BINDING, COMPETITIVE; BLOOD PLATELETS; BRAIN; CATTLE; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; LIGANDS; MEMBRANES; OXAZOLES; PROTEIN BINDING; RATS; RECEPTORS, PURINERGIC P1; RIBAVIRIN; RIBONUCLEOSIDES; RIBOSE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033877292     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00167-X     Document Type: Article

References (19)

1. Avery, T. L.; Hennen, W. J.; Revankar, G. R.; Robins, R. K. In New Avenues in Developmental Cancer Chemotherapy; Harrap, K. R.; Connors, T. A., Eds. Academic Press: New York, 1987, pp 367-385 and references therein.
2. Tricot G.J., Jayaram H.N., Weber G., Hiffman R. Int. J. Cell Cloning. 8:1990;161.
3. Trump D.L., Tuttsch K.D., Koeller J.M., Tormey D.C. Cancer Res. 45:1985;2853.
4. Franchetti P., Cappellacci L., Grifantini M., Senatore G., Martini C., Lucacchini A. Res. Commun. Molec. Path. Pharmacol. 87:1995;103.
5. (a) Franchetti, P.; Cristalli, G.; Grifantini, M.; Cappellacci, L.; Vittori, S.; Nocentini, G. J. Med. Chem. 1990, 33, 2849.
6. (b) Franchetti, P.; Messini, L.; Cappellacci, L.; Grifantini, M.; Guarracino, P.; Marongiu, M. E.; Piras, G.; La Colla, P. Nucleosides Nucleotides 1993, 12, 359.
7. Franchetti P., Cappellacci L., Grifantini M., Barzi A., Nocentini G., Yang H., O'Connor A., Jayaram H.N., Carrell C., Goldstein B.M. J. Med. Chem. 38:1995;3829.
8. Rosemeyer H., Toth G., Seela F. Nucleosides Nucleotides. 8:1989;587.
9. Borea P.A., Varani K., Malaguti V., Gilli G. J. Pharm. Pharmacol. 43:1991;866.
10. Peet N.P., Lentz N.L., Meng E.C., Dudley M.W., Ogden A.M.L., Demeter D.A., Weintraub H.J.R., Bey P. J. Med. Chem. 33:1990;3127.
11. (a) Stiles, G. L. J. Biol. Chem. 1985, 260, 6728.
12. (b) Jarvis, M. F.; Schulz, R.; Ilutchinson, A. J.; Do, U. H.; Sill, M. A.; Williams, M. J. Pharmacol. Exp. Ther. 1989, 251, 888.
13. Martini C., Pennacchi F., Poli M.G., Lucacchini A. Neurochem. Int. 7:1985;1017.
14. Cheng Y., Prusoff W.H. Biochem. Pharmacol. 22:1973;3099.
15. Rodbell M. J. Biol. Chem. 239:1964;375.
16. Borea P.A., Varani K., Dalpiaz A., Capuzzo A., Fabbri E., Ijzerman A.P. Eur. J. Pharmacol. 267:1994;55.
17. Korth R., Nunez D., Bidault J., Benveniste J. Eur. J. Pharmacol. 152:1988;101.
18. Varani K., Gessi S., Dalpiaz A., Borea P.A. Br. J. Pharmacol. 117:1996;1693.
19. Brown, B. L.; Ekins, R. P.; Albano, J. D. M. In Advances in Cyclic Nucleotide Research. Raven Press: New York, 1972, Vol. 2, p 25.