In vitro selection of fluoroquinolone-resistant Neisseria gonorrhoeae harboring alterations in DNA gyrase and topoisomerase IV

Journal of Urology

Volumn 164, Issue 3 I, 2000, Pages 847-851

  Yasuda, Mitsuru ^b   Fukuda, Hideyuki ^b   Yokoi, Shigeaki ^b   Ishihara, Satoshi ^b   Kawada, Yukimichi ^b   Deguchi, Takashi ^a  

^a GIFU UNIVERSITY   (Japan)

^b NONE

Author keywords

DNA gyrase; Fluoroquinolone resistance; Neisseria gonorrhoeae; Topoisomerase IV

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); NORFLOXACIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL MUTATION; BACTERIUM MUTANT; ESCHERICHIA COLI; GENE SEQUENCE; MINIMUM INHIBITORY CONCENTRATION; NEISSERIA GONORRHOEAE; NONHUMAN; PRIORITY JOURNAL;

EID: 0033873107     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0022-5347(05)67325-9     Document Type: Article

References (21)

1. Hooper, D. C. and Wolfson, J. S.: Fluoroquinolone antimicrobial agents. N Engl J Med, 324: 384, 1991
2. Centers for Disease Control and Prevention.: Guidelines for treatment of sexually transmitted diseases. Morbid Mortal Weekly Rep, 47(RR-1): 1, 1998
3. Knapp, J. S. and Koumans, E. H.: Neisseria and Branhamella. In: Manual of Clinical Microbiology. 7th ed. Edited by Murray, P. R., Baron, E. J., Pfaller, M. A., Tenover, F. C. and Yolken, R. H. Washington D. C.: ASM press, chapt 38, pp 586-603, 1999
4. Nakamura, S.: Mechanisms of quinolone resistance. J Infect Chemother, 3: 128, 1997
5. Deguchi, T., Yasuda, M., Nakano, M., Ozeki, S., Ezaki, T., Saito, I. and Kawada, Y.: Quinolone-resistant Neisseria gonorrhoeae: Correlation of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV with antimicrobial susceptibility profiles. Antimicrob Agents Chemother, 40: 1020, 1996
6. Deguchi, T., Yasuda, M., Maeda, S-H., Saito, I. and Kawada, Y.: Serotyping of quinolone-resistant Neisseria gonorrhoeae isolates with alterations in GyrA and ParC. J. Antimicrob. Chemother, 41: 417, 1998
7. Tanaka, M., Fukuda, H., Hirai, K., Hosaka, M., Matsumoto, T. and Kumazawa, J.: Reduced uptake and accumulation of norfloxacin in resistant strains of Neisseria gonorrhoeae isolated in Japan. Genitourin Med, 70: 253, 1994
8. Belland, R. J., Morrison, S. G., Ison and C., Hunag, W. M.: Neisseria gonorrhoeae acquires mutations in analogous regions of gyrA and parC in fluoroquinolone-resistant isolates. Mol Microbiol, 14: 371, 1994
9. Deguchi, T., Yasuda. M., Nakano, M., Ozeki. S., Ezaki, T., Maeda, S-I., Saito, I. and Kawada, Y.: Rapid detection of point mutations of the Neisseria gonorrhoeae gyrA gene associated with decreased susceptibilities to quinolones. J Clin Microbiol, 34: 2255, 1996
10. Deguchi, T., Yasuda, M., Nakano, M., Kanematsu, E., Ozeki, S., Nishino, Y., Ezaki, T., Maeda, S-I. and Kawada, Y.: Rapid screening of point mutations of the Neisseria gonorrhoeae parC gene associated with resistance to quinolones. J Clin Microbiol, 35: 948, 1997
11. National Committee for Clinical Laboratory Standards.: Approved standard M7-A3. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. National Committee for Clinical Laboratory Standards: Villanova, Pa., 1993
12. National Committee for Clinical Laboratory Standards.: Performance standards for antimicrobial susceptibility testing; ninth informational supplement. NCCLS document M100-S9, 19: 50, 1999
13. Deguchi, T., Yasuda, M., Nakano, M., Ozeki, S., Kanematsu, E., Kawada, Y., Ezaki, T. and Saito, I.: Uncommon occurrence of mutations in the gyrB gene associated with quinolone resistance in clinical isolates of Neisseria gonorrhoeas, Antimicrob Agents Chemother, 40: 2437, 1996
14. Tanaka, M., Takahashi, K., Saika, T., Kobayashi, I., Ueno, T. and Kumazawa, J.: Development of fluoroquinolone resistance and mutations involving GyrA and ParC proteins among Neisseria gonorrhoeae isolates in Japan. J Urol, 159: 2215, 1998
15. Stein, D., Danaher, R. J. and Cook, T. M.: Characterization of a gyrB mutation responsible for low-level nalidixic acid resistance in Neisseria gonorrhoeae. Antimicrob Agents Chemother, 35: 622, 1991
16. Perichon, B., Tankovic, J. and Courvalin, P.: Characterization of mutation in the parE gene that confers fluoroquinolone resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother, 41: 1166, 1997
17. Nikaido, H.: Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science, 264: 382, 1994
18. Gordon, S. M., Carlyn, C. J., Doyle, L. J., Knapp, C. C., Longworth, D. L., Hall, G. S. and Washington, J. A.: The emergence of Neisseria gonorrhoeae with decreased susceptibility to ciprofloxacin in Cleveland, Ohio: epidemiology and risk factors. Ann Intern Med, 125: 465, 1996
19. Kilmarx, P. H., Knapp, J. S., Xia, M., St. Louis, M. E., Neal, S. W., Sayers, D., Doyle, L. J., Roberts, M. C. and Whittington, W. L.: Intercity spread of gonococci with decreased susceptibility to fluoroquinolones: a unique focus in the United States. J Infect Dis, 177: 677, 1998
20. Kam, K. M., Wong, P. W., Cheung, M. M., Ho, N. K Y. and Lo, K. K.: Quinolone-resistant Neisseria gonorrhoeae in Hong Kong. Sex Trans Dis, 23: 103, 1996
21. Tapsall, J. W., Phillips, E. A., Shultz, T. R. and Thacker, C.: Quinolone-resistant Neisseria gonorrhoeae isolated in Sydney, Australia, 1991 to 1995. Sex Trans Dis, 23: 425, 1996