Electrophilic attack of [I(py)2]+(NO3-) on three-coordinate Pt0 precursors: Synthesis and in vitro antitumor activity of water-soluble, five- coordinate Pt(II) complexes

European Journal of Inorganic Chemistry

Volumn , Issue 8, 2000, Pages 1717-1721

  Bigioni, Mario ^a   Ganis, Paolo ^b   Panunzi, Achille ^b   Ruffo, Francesco ^b   Salvatore, Carmela ^a   Vito, Antonio ^c  

^a Menarini Ricerche SpA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c Algalite   (Italy)

Author keywords

Antitumor agents; Electrophilic additions; N ligands; Platinum; Water soluble complexes

Indexed keywords

CHELATION; CRYSTAL STRUCTURE; OLEFINS; PLATINUM COMPOUNDS; PYRIDINE; SYNTHESIS (CHEMICAL);

ANTITUMOUR AGENTS; ELECTROPHILIC ADDITIONS; ELECTROPHILIC ATTACK; IN-VITRO; METHYLPYRIDINE; N LIGANDS; N-LIGANDS; PRECURSOR SYNTHESIS; VITRO ANTITUMOR ACTIVITIES; WATER-SOLUBLE COMPLEXES;

CELL CULTURE;

CISPLATIN DERIVATIVE; PLATINUM DERIVATIVE; PLATINUM[2 METHYL 6 [(PHENYLIMINO)METHYL]PYRIDINE]1(PY)(METHYLACRYLATE)] NITRIC OXIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; METAL BINDING; OXIDATION; SOLUBILITY; SYNTHESIS;

EID: 0033868637     PISSN: 14341948     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-0682(200008)2000:8<1717::aid-ejic1717>3.0.co;2-1     Document Type: Article

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