Prevention of glutaraldehyde-fixed bioprosthetic heart valve calcification by alcohol pretreatment: Further mechanistic studies

Journal of Heart Valve Disease

Volumn 9, Issue 4, 2000, Pages 561-566

  Vyavahare, Narendra R ^a,b,e   Jones, Peter Lloyd ^a,b   Hirsch, Danielle ^c   Schoen, Frederick J ^d   Levy, Robert J ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e AMRL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 PROPANOL; ALCOHOL; CALCIUM; COLLAGENASE; GLUTARALDEHYDE; METHANOL; PHOSPHORUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOPROSTHESIS; CALCIFICATION; CATTLE; CONTROLLED STUDY; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; GRAFT FAILURE; HEART VALVE PROSTHESIS; HYDROLYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PERICARDIUM; PRIORITY JOURNAL; RAT; SOLID STATE; STORAGE; TISSUE FIXATION;

2-PROPANOL; ANIMALS; AORTIC VALVE; BIOPROSTHESIS; CALCINOSIS; CATTLE; ETHANOL; HEART VALVE PROSTHESIS; HEART VALVE PROSTHESIS IMPLANTATION; MALE; METHANOL; PERICARDIUM; RATS; RATS, SPRAGUE-DAWLEY; SWINE;

EID: 0033868574     PISSN: 09668519     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Vyavahare N, Hirsch D, Lerner E, et al. Prevention of bioprosthetic heart valve calcification by ethanol preincubation. Efficacy and mechanisms (see comments). Circulation 1997;95:479-488
2. Vyavahare NR, Hirsch D, Lerner E, et al. Prevention of calcification of glutaraldehyde-crosslinked porcine aortic cusps by ethanol preincubation: Mechanistic studies of protein structure and water-biomaterial relationships. J Biomed Mater Res 1998;40:577-585
3. Lee CH, Vyavahare N, Zand R, et al. Inhibition of aortic wall calcification in bioprosthetic heart valves by ethanol pretreatment: Biochemical and biophysical mechanisms. J Biomed Mater Res 1998;42:30-37
4. Schoen FJ, Levy RJ, Nelson AC, et al. Onset and progression of experimental bioprosthetic heart valve calcification. Lab Invest 1985;52:523-532
5. Chen P, Toribara T, Warner H. Microdetermination of phosphorus. Anal Chem 1956;28:1756
6. Gratzer PF, Pereira CA, Lee JM. Solvent environment modulates effects of glutaraldehyde crosslinking on tissue-derived biomaterials. J Biomed Mater Res 1996;31:533-543
7. Boudreau NJ, Jones PL. Extracellular matrix and integrin signaling: The shape of things to come. Biochem J 1999;339:481-488
8. Mackie EJ. Tenascin in connective tissue development and pathogenesis. Perspect Dev Neurobiol 1994;2:125-132
9. Mackie EJ, Ramsey S. Expression of tenascin in joint-associated tissues during development and postnatal growth. J Anat 1996;188(Pt.1):157-165
10. Mighell AJ, Robinson PA, Hume WJ. Immunolocalization of tenascin-C in focal reactive overgrowths of oral mucosa. J Oral Pathol Med 1996;25:163-169
11. Pacifici M. Tenascin-C and the development of articular cartilage. Matrix Biol 1995;14:689-698
12. Mackie EJ, Ramsey S. Modulation of osteoblast behavior by tenascin. J Cell Sci 1996;109(Pt.6):1597-1604
13. Cowan KN, Jones PL, Rabinovitch M. Regression of hypertrophied rat pulmonary arteries in organ culture is associated with suppression of proteolytic activity, inhibition of tenascin-C, and smooth muscle cell apoptosis. Circ Res 1999;84:1223-1233
14. Jones PL, Crack J, Rabinovitch M. Regulation of tenascin-C, a vascular smooth muscle cell survival factor that interacts with the alpha v beta 3 integrin to promote epidermal growth factor receptor phosphorylation and growth. J Cell Biol 1997;139:279-293
15. Jones PL, Jones FS, Zhou B, Rabinovitch M. Induction of vascular smooth muscle cell tenascin-C gene expression by denatured type I collagen is dependent upon a beta3 integrin-mediated mitogen-activated protein kinase pathway and a 122-base pair promoter element. J Cell Sci 1999;112:435-445