Selective gene expression in hepatic tumor with trans-arterial delivery of DNA/liposome/transferrin complex

In Vivo

Volumn 14, Issue 4, 2000, Pages 513-517

  Seol, J G ^a   Heo, D S ^a   Kim, H K ^a   Yoon, J H ^a   Choi, B I ^a   Lee, H S ^a   Kim, N K ^a   Kim, C Y ^a  

^a Seoul National University Hospital   (South Korea)

Author keywords

Gene delivery; Hepatocellular carcinoma; Liposome; Trans arterial; VX2 carcinoma

Indexed keywords

BETA GALACTOSIDASE; LIPOFECTIN; RECOMBINANT DNA; TRANSFERRIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOMA CELL; GENE TARGETING; GENE THERAPY; GENE TRANSFER; HEPATIC ARTERY; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; NONHUMAN; RABBIT; TRANSGENE;

EID: 0033865915     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. P53 gene therapy in a rat model of hepatocellular carcinoma: Intraarterial delivery of a recombinant adenovirus
2. Hepatocellular carcinoma
3. Treatment of hepatocellular carcinoma: Too many options?
4. Lipofection: A highly efficient, lipid-mediated DNA-tansfection procedure
5. Use of a quaternary ammonium detergent in liposome-mediated DNBA transfection of mouse L-cells
6. A novel cationic liposome reagent for efficient transfection of mammalian cells
7. The blood supply of neoplasms in the liver
8. Recombinant gene expression in vivo within endothelial cells of the arterial wall
9. Direct in vivo gene transfer into the coronary and peripheral vasculatures of the intact dog
10. Receptor-mediated DNA delivery approaches to human gene therapy
11. Transferrin as a targeting ligand for liposomes and anticancer drugs
12. Gene delivery into human cancer cells via transferrin receptor
13. Establishment of continuous human fetal hepatocyte cell line by transfection of simian virus 40 T gene
14. Development of a non-transformed liver cell line with differentiated hepatocyte and urea-synthetic functions: Applicable for bioartificial liver
15. Animal model: VX-2 carcinoma of rabbits
16. Improved rabbit brain tumor model amenable to diagnostic radio-graphic procedures
17. A reproducible model of metastatic brain and ocular tumor by hematogenous inoculation of the VX-2 tumor in rabbits
18. Hepatic artery versus portal vein and systemic infusion of fluorodeoxyuridine of rabbit VX-2 hepatic implants
19. Transcatheter arterial embolization as a method of cisplatin retention enhancement on the VX-2 tumor uterus transplants
20. Retroviruses: Delivery vehicle to the liver
21. Evaluation of the transfer and expression in mice of an enzyme encoding gene using a human adenovirus vector
22. Adenovirus-mediated in vivo gene transfer and expression in normal rat liver
23. Assessment of recombinant adenoviral vectors for hepatic gene therapy
24. Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagese rats
25. Direct injection of hepatitis B virus DNA into liver induced hepatitis in adult rats
26. Systemic gene expression after intravenous DNA delivery into adult mice
27. Liver directed gene therapy: Prospects and problems
28. Cationic liposome-mediated transfection
29. Hepatic gene transfer in animals using retroviruses containing the promoter from the gene phosphoenolpyruvate carboxykinase
30. Percutaneous hepatic vein isolation and high-dose hepatic arterial infusion chemotherapy for unresectable liver tumors
31. Arterial infusion chemotherapy for advanced hepatocellular carcinoma using EPF and EAP therapies
32. Hepatic arterial chemotherapy for colorectal cancer metastatic to the liver
33. Gene expression following direct injection of DNA into liver
34. Surgery for hepatic neoplasms
35. Enhanced in vivo adenovirus-mediated gene transfer to rat hepatocarcinomas by selective administration into the hepatic artery