AmtR, a global repressor in the nitrogen regulation system of Corynebacterium glutamicum

Molecular Microbiology

Volumn 37, Issue 4, 2000, Pages 964-977

  Jakoby, Marc ^a,b   Nolden, Lars ^a   Meier Wagner, Jana ^a   Krämer, Reinhard ^a   Burkovski, Andreas ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b MAX PLANCK INSTITUTE FOR PLANT BREEDING RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; BETA GALACTOSIDASE; HEXOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; NITROGEN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CORYNEBACTERIUM GLUTAMICUM; DNA HYBRIDIZATION; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE SEQUENCE; NITROGEN FIXATION; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPERON; PRIORITY JOURNAL; PROTEIN DNA BINDING; REPRESSOR GENE; TRANSCRIPTION REGULATION; YEAST;

AMINO ACID SEQUENCE; ARTIFICIAL GENE FUSION; BACTERIAL PROTEINS; BASE SEQUENCE; CORYNEBACTERIUM; DNA, BACTERIAL; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; NITROGEN; PROTEIN BINDING; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); CORYNEBACTERIUM GLUTAMICUM; ENTEROBACTERIA; ENTEROBACTERIACEAE; ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NEGIBACTERIA; POSIBACTERIA;

EID: 0033865395     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2000.02073.x     Document Type: Article

References (40)

1. Abe, S., Takayama, K., and Kinoshita, S. (1967) Taxonomical studies on glutamic acid-producing bacteria. J Gen Microbiol 13: 279-301.
2. Atkinson, M.R., and Ninfa, A.J. (1998) Role of the GlnK signal transduction protein in the regulation of nitrogen assimilation in Escherichia coli. Mol Microbiol 29: 431-447.
3. Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A., and Struhl, K. (1987). Current Protocols in Molecular Biology. New York: John Wiley and Sons.
4. Beynon, J., Cannon, M., Buchanan-Wollaston, V., and Cannon, F. (1983) The nif promoters of Klebsiella pneumoniae have a characteristic primary structure. Cell 34: 665-667.
5. Börmann, E.R., Eikmanns, B.J., and Sahm, H. (1992) Molecular analysis of the Corynebacterium glutamicum gdh gene encoding glutamate dehydrogenase. Mol Microbiol 6: 317-326.
6. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein - dye binding. Anal Biochem 72: 248-254.
7. Cremer, J., Eggeling, L., and Sahm, H. (1990) Cloning the dapA dapB cluster of the lysine-secreting bacterium Corynebacterium glutamicum. Mol Gen Genet 220: 478-480.
8. Eikmanns, B.J., Thum-Schmitz, N., Eggeling, L., Lüdtke, K.-U., and Sahm, H. (1994) Nucleotide sequence, expression and transcriptional analysis of the Corynebacterium glutamicum gltA gene encoding citrate synthase. Microbiology 140: 1817-1828.
9. Fisher, S.H. (1999) Regulation of nitrogen metabolism in Bacillus subtilis: vive la différence!. Mol Microbiol 32: 223-232.
10. Grant, S.N.G., Jessee, J., Bloom, F.R., and Hanahan, D. (1990) Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants. Proc Natl Acad Sci USA 87: 4645-4649.
11. Guan, C., Li, P., Riggs, P.D., and Inouye, H. (1987) Vectors that facilitate the expression and purification of foreign peptides in Escherichia coli by fusion to maltose-binding protein. Gene 67: 21-30.
12. Imai, Y., Matsushima, Y., Sugimura, T., and Terada, M. (1991) A simple and rapid method for generating deletions by PCR. Nucleic Acids Res 19: 2785.
13. Jakoby, M., Tesch, M., Sahm, H., Krämer, R., and Burkovski, A. (1997) Isolation of the Corynebacterium glutamicum glnA gene encoding glutamine synthetase I. FEMS Microbiol Lett 154: 81-88.
14. Jakoby, M., Krämer, R., and Burkovski, A. (1999) Nitrogen regulation in Corynebacterium glutamicum: Isolation of genes involved and biochemical characterization of the corresponding proteins. FEMS Microbiol Lett 173: 303-310.
15. Jayakumar, A., Hong, J.-S., and Barnes, Jr, E.M. (1986) Feedback inhibition of ammonium (methylammonium) ion transport in Escherichia coli by glutamine and glutamine analogs. J Bacteriol 169: 553-557.
16. Keilhauer, C., Eggeling, L., and Sahm, H. (1993) Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operon. J Bacteriol 175: 5595-5603.
17. Kleiner, D. (1985) Bacterial ammonium transport. FEMS Microbiol Rev 32: 87-100.
18. + transport systems. In Alkali Cation Transport Systems in Prokaryotes. Bakker, E.P. (ed.). Boca Raton, FL: CRC Press, pp. 379-395.
19. Kleiner, D., and Castorph, H. (1982) Inhibition of ammonium (methylammonium) transport in Klebsiella pneumoniae by glutamine and glutamine analogues. FEBS Lett 146: 201-203.
20. Laemmli, U.K. (1970) Cleavage of structural proteins during assembly of bacteriophage T4. Nature 227: 680-685.
21. Liu, J.J., and Herskowitz, I. (1993) Isolation of ORC6, a component of the yeast origin of recognition complex by a one-hybrid system. Science 262: 1870-1873.
22. Magasanik, B. (1996) Regulation of nitrogen utilization. In Escherichia coli and Salmonella: Cellular and Molecular Biology. Neidhardt, F.C., Curtiss, III, R., Ingraham, J.L., Lin, E.C.C., Low, K.B., Magasanik, B. et al. (eds). Washington, DC: American Society for Microbiology Press, pp. 1344-1356.
23. Merrick, M.J., and Edwards, R.A. (1995) Nitrogen control in bacteria. Microbiol Rev 59: 604-622.
24. Michel-Reydellet, N., Desnoues, N., de Zamaroczy, M., Elmerich, C., and Kaminski, P.A. (1998) Characterization of the glnK-amtB operon and the involvement of AmtB in methylammonium uptake in Azorhizobium caulinodans. Mol Gen Genet 258: 671-677.
25. Miller, J.H. (1972) Experiments in Molecular Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
26. Montesinos, M.L., Muro-Pastor, A.M., Herrero, A., and Flores, E. (1998) Ammonium/methylammonium permeases of a cyanobacterium. J Biol Chem 273: 31463-31470.
27. Pátek, M., Eikmanns, B.J., Pátek, J., and Sahm, H. (1996) Promoters of Corynebacterium glutamicum: cloning, molecular analysis and search for a consensus motif. Microbiology 142: 1297-1309.
28. Reitzer, L.J. (1996) Sources of nitrogen and their utilization. In Escherichia coli and Salmonella: Cellular and Molecular Biology. Neidhardt, F.C., Curtiss, III, R., Ingraham, J.L., Lin, E.C.C., Low, K.B., Magasanik, B. et al. (eds). Washington, DC: American Society for Microbiology Press, pp. 380-390.
29. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1989) Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
30. Schäfer, A., Tauch, A., Jäger, W., Kalinowski, J., Thierbach, G., and Pühler, A. (1994) Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: Selection of defined deletions in the chromosome of Corynebacterium glutamicum. Gene 145: 69-73.
31. Siewe, R.M., Weil, B., Burkovski, A., Eikmanns, B.J., Eikmanns, M., and Krämer, R. (1996) Functional and genetic characterization of the (methyl)ammonium uptake carrier of Corynebacterium glutamicum. J Biol Chem 271: 5398-5403.
32. Simon, R., Priefer, U., and Pühler, A. (1983) A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram-negative bacteria. Appl Microbiol Biotechnol 1: 784-791.
33. Studier, F.W., Rosenberg, A.H., Dunn, J.J., and Dubendorff, J.W. (1990) Use of T7 polymerase to direct expression of cloned genes. In Methods Enzymol, Vol. 185. San Diego, CA: Academic Press, pp. 60-89.
34. Thomas, G., Coutts, G., and Merrick, M. (2000) The glnKamtB operon, a conserved gene pair in prokaryotes. Trends Genet 16: 11-14.
35. Van Dommelen, A., Keijers, V., Vanderleyden, J., and de Zamaroczy, M. (1998) (methyl)ammonium transport in the nitrogen-fixing bacterium Azospirillum brasiliense. J Bacteriol 180: 2652-2659.
36. II protein in the regulation of glutamine synthetase in Escherichia coli. Mol Microbiol 21: 133-146.
37. Wilson, T.E., Fahrner, T.J., Johnston, M., and Milbrandt, J. (1991) Identification of the DNA binding site for NGFI-B by genetic selection in yeast. Science 252: 1296-1230.
38. II protein. J Bacteriol 176: 108-114.
39. Wray, Jr, L.V., Zalieckas, J.M., and Fisher, S. (1998) Mutational analysis of the TnrA-binding sites in the Bacillus subtilis nrgAB and gabP promoter regions. J Bacteriol 180: 2943-2949.
40. Yanisch-Perron, C., Vieira, L., and Messing, J. (1985) Improved M13 phage cloning vectors and host strains: Nucleotide sequences of M13mp18 and pUC19 vectors. Gene 33: 103-119.