Effect of fluorine substitution on the interaction of lipophilic ions with the plasma membrane of mammalian cells

Biophysical Journal

Volumn 79, Issue 3, 2000, Pages 1490-1497

  Kürschner, Markus ^a   Nielsen, Katja ^a   Von Langen, Johannes R G ^a   Schenk, Wolfdieter A ^a   Zimmermann, Ulrich ^a   Sukhorukov, Vladimir L ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANION; CARBONYL DERIVATIVE; FLUORINE; FLUORINE DERIVATIVE; TUNGSTEN DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CHEMICAL INTERACTION; CYTOPLASM; ELECTRICITY; ION TRANSPORT; LIPOPHILICITY; MAMMAL CELL; MOUSE; NONHUMAN; PARTITION COEFFICIENT; SURFACE PROPERTY;

EID: 0033864598     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76400-9     Document Type: Article

References (6)

1. Almotrefi, A. A., N. Dzimiri, H. Y. Aboul-Enein, and L. S. Premkumar. 1993. Synthesis and pharmacological evaluation of the antifibrillatory effect of fluorinated derivatives of carazolol and celiprolol: comparison with propranolol. Gen. Pharmacol. 24:721-725.
2. Arnold, W. M., and U. Zimmermann. 1982. Rotating-field-induced rotation and measurement of the membrane capacitance of single mesophyll cells of Avena sativa. Z. Naturforsch. 37c:908-915.
3. Arnold, W. M., U. Zimmermann, W. Heiden, and J. Ahlers. 1988. The influence of tetraphenylborates (Hydrophobic anions) on yeast cell electro-rotation. Biochim. Biophys. Acta. 942:96-106.
4. Asuquo, A. E., and L. J. Piddock. 1993. Accumulation and killing kinetics of fifteen quinolones for Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. J. Antimicrob. Chemother. 31:865-880.
5. Barnard, S., R. C. Storr, P. M. O'Neill, and B. K. Park. 1993. The effect of fluorine substitution on the physicochemical properties and the analgesic activity of paracetamol. J. Pharm. Pharmacol. 45:736-744.
6. Benz, R. 1988. Structural requirement for the rapid movement of charged molecules across membranes. Experiments with tetraphenylborate analogues. Biophys. J. 54:25-33.