Analysis of neurotoxin 3-N-oxalyl-L-2,3-diaminopropionic acid and its α-isomer in Lathyrus sativus by high-performance liquid chromatography with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC) derivatization

Journal of Agricultural and Food Chemistry

Volumn 48, Issue 8, 2000, Pages 3383-3386

  Chen, X ^b   Wang, F ^a   Chen, Q ^a   Xing Chen Qin, ^b   Li, Z ^a  

^a LANZHOU UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

Author keywords

6 Aminoquinolyl N hydroxysuccinimidyl carbamate; Lathyrus sativus; Neurotoxin; RP HPLC

Indexed keywords

3 N OXALYL LEVO 2,3 DIAMINOPROPIONIC ACID; 6 AMINOQUINOLYL N HYDROXYSUCCINIMIDYL CARBAMATE; 6-AMINOQUINOLYL-N-HYDROXYSUCCINIMIDYL CARBAMATE; AMINOQUINOLINE DERIVATIVE; CARBAMATE INSECTICIDE; CARBAMIC ACID DERIVATIVE; DIAMINO ACID; NEUROTOXIN; OXALYLDIAMINOPROPIONIC ACID; PROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMISTRY; COLORIMETRY; DERIVATIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERISM; LEGUME; METHODOLOGY; NEUROTOXICITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SAMPLING;

AMINO ACIDS, DIAMINO; AMINOQUINOLINES; CARBAMATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FABACEAE; ISOMERISM; NEUROTOXINS; PLANTS, MEDICINAL;

LATHYRUS SATIVUS;

EID: 0033864283     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf000033y     Document Type: Article

References (14)

1. Synthesis of a fluorescent derivatizing reagent,6-aminoquinolyl-N-hydroxysuccinimidyl carbamate, and its application for the analysis of hydrolysate amino acids via high-performance liquid chromatography
2. Determination of the neurolathyrogen β-N-oxalyl-L-α-,β-diaminopropionic acid using high-performance liquid chromatography with fluorometric detection
3. Synthesis of α- and β-N-oxalyl-α-,β-diaminopropionic acids and their isolation from seeds of Lathyrus sativus
4. Analysis of the neurotoxin β-ODAP and its α-isomer by precolumn derivatizatoin with phenylisothiocyanate
5. Determination of α- and β-oxalyldiaminopropionic acid in Lathyrus sativus by electrophoresis
6. A sensitive and specific colorimetric method for the determination of α,β-diaminopropionic acid and the Lathyrus sativus neurotoxin
7. Neurotoxic action of β-(N-oxalyl)-L-α-,β-diaminopropionic acid
8. The isolation and characterization of β-N-oxalyl-L-α,β-diaminopropionic acid: A neurotoxin from the seeds of Lathyrus sativus
9. β-N-oxalylamino-L-alanine: Action on high-affinity transport of neurotransmitters in rat brain and spiral cord synaptosomes
10. High performance lquid chromatography of nonprotein amino acids extracted from Acacia seeds
11. The need for a strain lacking human and animal neurotoxic properties
12. Pattern of Lathyrus sativus (Grass pea) consumption and beta-N-oxalyl-2,3-diaminopropionic acid (β-ODAP) content of food samples in the lathyrism endemic region of Northwest Ethiopia
13. L-2-Oxalylamino-3-amino-propionic acid, an isomer of Lathyrus sativus neurotoxin
14. Analysis of β-N-oxalyl-α,β-diaminopropionic acid and homoarginine in Lathyrus sativus by capillary zone electrophoresis