Human immunodeficiency virus type 1 Vif protein is an integral component of an mRNP complex of viral RNA and could be involved in the viral RNA folding and packaging process

Journal of Virology

Volumn 74, Issue 18, 2000, Pages 8252-8261

  Zhang, H ^a   Pomerantz, R J ^a   Dornadula, G ^a   Sun, Y ^a  

^a Center for Human Virology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; RNA BINDING PROTEIN; VIF PROTEIN; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOID CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN RNA BINDING; REVERSE TRANSCRIPTION; RNA PROCESSING; RNA STRUCTURE; VIRION; VIRUS INFECTIVITY; VIRUS REPLICATION;

AMINO ACID SEQUENCE; CELL LINE; GENE PRODUCTS, GAG; GENE PRODUCTS, VIF; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RIBONUCLEOPROTEINS; RNA, VIRAL; RNA-BINDING PROTEINS; SEQUENCE ALIGNMENT; VIRUS ASSEMBLY;

EID: 0033863969     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.18.8252-8261.2000     Document Type: Article

References (70)

1. Interaction of mRNA with proteins in vesicular stomatitis virus-infected cells
2. The human poly(A)-binding protein 1 shuttles between the nucleus and the cytoplasm
3. Replication and pathogenicity of human immunodeficiency virus type 1 accessory gene mutants in SCID-hu mice
4. RNA packaging
5. Specific binding of human immunodeficiency virus type 1 Gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays
6. A study of the dimer formation of Rous sarcoma virus RNA and of its effect on viral protein synthesis in vitro
7. Transcomplementation of VIF- HIV-1 mutants in CEM cells suggests that VIF affects late steps of the viral life cycle
8. - mutant particles from restrictive cells: Role of Vif in correct particle assembly and infectivity
9. Human immunodeficiency virus type 1 Vif protein binds to the Pr55(Gag) precursor
10. - human immunodeficiency virus type 1 is produced by chronically infected restrictive cells
11. Conserved structures and diversity of functions of RNA-binding proteins
12. RNA binding specificity of hnRNP A1: Significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing
13. Characterization of human immunodeficiency virus type 1 Vif particle incorporation
14. A mutant of human immunodeficiency virus with reduced RNA packaging and abnormal particle morphology
15. RNA secondary structure and binding sites for gag gene products in the 5' packaging signal of human immunodeficiency virus type 1
16. Structure of the retroviral genome
17. - human immunodeficiency virus type 1 particles which are restricted for the preretrotranscription steps
18. Gag, vif and nef genes contribute to the homologous viral interference induced by a nonproducer human immunodeficiency virus type 1 (HIV-1) variant: Identification of novel HIV1-inhibiting viral protein mutants
19. Specific binding of HIV-1 nucleocapsid protein to PSI RNA in vitro requires N-terminal zinc finger and flanking basic amino acid residues
20. First glimpses at structure-function relationships of the nucleocapsid protein of retroviruses
21. Binding sites of viral protein P19 onto Rous sarcoma virus RNA and possible controls of viral functions
22. Identification of highly attenuated mutants of simian immunodeficiency virus
23. Highly purified human immunodeficiency virus type 1 reveals a virtual absence of Vif in virions
24. Partial rescue of the Vif-negative phenotype of mutant human immunodeficiency virus type 1 strains from nonpermissive cells by intravirion reverse transcription
25. Structure and function of nuclear and cytoplasmic ribonucleoprotein particles
26. hnRNP proteins and the biogenesis of mRNA
27. The major core protein of messenger ribonucleoprotein particles (p50) promotes initiation of protein biosynthesis in vitro
28. The major protein of messenger ribonucleoprotein particles in somatic cells is a member of the Y-box binding transcription factor family
29. The sor gene of HIV-1 is required for efficient virus transmission in vitro
30. Sequence-specific binding of human immunodeficiency virus type 1 nucleocapsid protein to short oligonucleotides
31. Human immunodeficiency virus type 1 Vif does not influence expression or virion incorporation of gag-, pol-, and env-encoded proteins
32. + T lymphocytes
33. Essential role of vif in establishing productive HIV-1 infection in peripheral blood T lymphocytes and monocyte/macrophages
34. Construction and in vitro properties of HIV-1 mutants with deletions in 'nonessential' genes
35. Subcellular localization of the Vif protein of human immunodeficiency virus type 1
36. Role of Vif in human immunodeficiency virus type 1 reverse transcription
37. RNA chaperones and the RNA folding problem
38. Role of vif during packing of the core of HIV-1
39. Interaction and coencapsidation of human immunodeficiency virus type 1 Gag and Vif recombinant proteins
40. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells
41. Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions
42. An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein
43. Translational repression dependent on the interaction of the Xenopus Y-box protein FRGY2 with mRNA. Role of the cold shock domain, tail domain, and selective RNA sequence recognition
44. Tables for estimating sedimentation through linear concentration gradients of sucrose solution
45. The double-stranded RNA-binding protein Staufen is incorporated in human immunodeficiency virus type 1: Evidence for a role in genomic RNA encapsidation
46. Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants
47. Purification and visualization of native spliceosomes
48. Inhibition of protein synthesis in vesicular stomatitis virus infected Chinese hamster ovary cells: Role of virus mRNA-ribonucleoprotein particle
49. A quantitative reverse transcriptase-polymerase chain reaction for HIV-1-specific RNA species
50. Impact of human immunodeficiency virus type 1 RNA dimerization on viral infectivity and of stem-loop B on RNA dimerization and reverse transcription and dissociation of dimerization from packaging
51. Vif and the p55(Gag) polyprotein of human immunodeficiency virus type 1 are present in colocalizing membrane-free cytoplasmic complexes
52. The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells
53. Evidence for a newly discovered cellular anti-HIV-1 phenotype
54. The human immunodeficiency virus type 1 Vif protein modulates the postpenetration stability of viral nucleoprotein complexes
55. Virion incorporation of human immunodeficiency virus type-1 Vif is determined by intracellular expression level and may not be necessary for function
56. The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted: A role for Vif in determining virus host range and cross-species transmission
57. Complementation of vif-defective human immunodeficiency virus type 1 by primate, but not nonprimate, lentivirus vif genes
58. Conservation of an intact human immunodeficiency virus type 1 vif gene in vitro and in vivo
59. Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1
60. The HIV 'A' (sor) gene product is essential for virus infectivity
61. Classification and purification of proteins of heterogeneous nuclear ribonucleoprotein particles by RNA-binding specificities
62. HIV accessory proteins: Leading roles for the supporting cast
63. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
64. Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells
65. A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA
66. In vivo genetic variability of the HIV-1 vif gene
67. Diversity of the vif gene of human immunodeficiency virus type 1 in Uganda
68. Amphipathic domains in the C terminus of the transmembrane protein (gp41) permeabilize HIV-1 virions: A molecular mechanism underlying natural endogenous reverse transcription
69. Endogenous reverse transcription of human immunodeficiency virus type 1 in physiological microenvironments: An important stage for viral infection of nondividing cells
70. Reverse transcription takes place within extracellular HIV-1 virions: Potential biological significance