Optimizing the bioavailability of itraconazole

Connecticut Medicine

Volumn 64, Issue 7, 2000, Pages 415-417

  Grant, Edward M ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ANTIMYCOBACTERIAL AGENT; BENZODIAZEPINE; BUSULFAN; CALCIUM CHANNEL BLOCKING AGENT; CARBAMAZEPINE; CLARITHROMYCIN; DIGOXIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT; INDINAVIR; ISONIAZID; ITRACONAZOLE; NEVIRAPINE; OMEPRAZOLE; PHENOBARBITAL; PHENYTOIN; PROTEINASE INHIBITOR; PROTON PUMP INHIBITOR; QUINIDINE; RANITIDINE; RIFABUTIN; RIFAMPICIN; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SUCRALFATE; UNINDEXED DRUG; VINCA ALKALOID;

AREA UNDER THE CURVE; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG COMPETITION; DRUG FORMULATION; FOOD DRUG INTERACTION; HUMAN; SHORT SURVEY; STOMACH SECRETION;

ANTIFUNGAL AGENTS; BIOLOGICAL AVAILABILITY; CAPSULES; DRUG INTERACTIONS; HUMANS; ITRACONAZOLE; SOLUTIONS;

EID: 0033863742     PISSN: 00106178     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (6)

1. Van Peer A, Woestenborghs R, Heykants J, et al: The effect of food and dose on the oral systemic availability of itraconazole in healthy subjects. Eur J Clin Pharmacol 1989; 36:423-6.
2. Jaruratanasirikul S, Sriwiriyajan S: Effect of omeprazole on the pharmacokinetics of itraconazole. Eur J Clin Pharmacol 1998; 54: 159-61.
3. Lange D, Pavao JH, Wu J, Klausner M: Effect of a cola beverage on the bioavailability of itraconazole in the presence of H. blockers. J Clin Pharmacol 1997; 37:535-40.
4. MOSBY's GENRx™ - The Complete Reference for Generic and Brand Drugs - 10th Ed.: 2000.
5. Barone JA, Moskovitz BL, Guarnieri J, et al: Enhanced bioavailability of itraconazole in hydroxypropyl-β-cyclodextrin solution vs capsules in healthy volunteers. Antimicrob Agents Chemother 1998; 42:1862-5.
6. Barone JA, Moskovitz BL, Guarnieri J, et al: Food interaction and steady-state pharmacokinetics of itraconazole oral solution in healthy volunteers. Pharmacotherapy 1998; 18:295-301.