Anaplastic osteosarcoma with abundant eosinophilic cytoplasm and minimal osteoid production

Pathology International

Volumn 50, Issue 7, 2000, Pages 553-557

  Yamamoto, Tetsuji ^a,c   Marui, Takashi ^a   Mizuno, Kosaku ^a   Kizaki, Tomohiko ^b   Minami, Rieko ^a   Hanioka, Keisuke ^a   Hayashi, Yoshitake ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Hyogo Adult Disease Center   (Japan)

^c KOBE UNIVERSITY   (Japan)

Author keywords

Osteocalcin; Osteosarcoma; Tibia

Indexed keywords

OSTEOCALCIN; VIMENTIN;

ANAPLASTIC CARCINOMA; ARTICLE; AUTOPSY; BONE RADIOGRAPHY; BONE TISSUE; CASE REPORT; CHILD; ENDOPLASMIC RETICULUM; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; OSTEOLYSIS; OSTEOSARCOMA; PERIPHERAL NERVE; PRIORITY JOURNAL; TIBIA;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE NEOPLASMS; CHILD; CISPLATIN; CYTOPLASM; DOXORUBICIN; DRUG THERAPY, COMBINATION; EOSINE YELLOWISH-(YS); FATAL OUTCOME; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; METHOTREXATE; NEOPLASM PROTEINS; OSTEOSARCOMA; STAINING AND LABELING; TIBIA; TOMOGRAPHY, X-RAY COMPUTED; TUMOR MARKERS, BIOLOGICAL;

EID: 0033863605     PISSN: 13205463     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1827.2000.01077.x     Document Type: Article

References (11)

1. 1 Dahlin DV, Unni KK, eds. Bone Tumors: General Aspects and Data on 8542 Cases, 4th edn. Charles C Thomas, Springfield, 1986.
2. 2 Huvos AG, ed. Bone Tumors Diagnosis, Treatment, and Prognosis, 2nd edn. WB Saunders, Philadelphia, 1991.
3. 3 Ballance WA Jr, Mendelsohn G, Carter JR, Abdul-Karim FW, Jacobs G, Makley JT. Osteogenic sarcoma. Malignant fibrous histiocytoma subtype. Cancer 1988; 62: 763-771.
4. 4 Sugano I, Tajima Y, Ishida Y et al. Phalangeal intraosseous well-differentiated osteosarcoma of the hand. Virchows Arch. 1997; 430: 185-189.
5. 5 Hasegawa T, Shibata T, Hirose T, Seki K, Hizawa K. Osteosarcoma with epithelioid features. An immunohistochemical study. Arch. Pathol. Lab. Med. 1993; 117: 295-298.
6. 6 Vermeulen AH, Vermeer C, Bosman FT. Histochemical detection of osteocalcin in normal and pathological human bone. J. Histochem. Cytochem. 1989; 37: 1503-1508.
7. 7 Takada J, Ishii S, Ohta T et al. Usefulness of a novel monoclonal antibody against human osteocalcin in immunohistochemical diagnosis. Virchows Arch. A Pathol. Anat. Histopathol. 1992; 420: 507-511.
8. 8 Fanburg JC, Rosenberg AE, Weaver DL et al. Osteocalcin and osteonectin immunoreactivity in the diagnosis of osteosarcoma. Am. J. Clin. Pathol. 1997; 108: 464-473.
9. 9 Chano T, Matsumoto K, Ishizawa M et al. Analysis of the presence of osteocalcin, S-100 protein, and proliferating cell nuclear antigen in cells of various types of osteosarcomas. Eur. J. Histochem. 1996; 40: 189-198.
10. 10 Fanburg-Smith JC, Bratthauer GL, Miettinen M. Osteocalcin and osteonectin immunoreactivity in extraskeletal osteosarcoma: a study of 28 cases. Hum. Pathol. 1999; 30: 32-38.
11. 11 Kramer K, Hicks DG, Palis J et al. Epithelioid osteosarcoma of bone. Immunocytochemical evidence suggesting divergent epithelial and mesenchymal differentiation in a primary osseous neoplasm. Cancer 1993; 71: 2977-2982.