The effects of intrathecal morphine encapsulated in L- and D-dipalmitoylphosphatidyl choline liposomes on acute nociception in rats

Anesthesia and Analgesia

Volumn 91, Issue 2, 2000, Pages 423-428

  Nishiyama, Tomoki ^a,b,e   Ho, Rodney J Y ^c   Shen, Danny D ^c,d   Yaksh, Tony L ^a  

^a University of California   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Fred Hutchinson Cancer Research Center   (United States)

^e NONE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALFENTANIL; DIPALMITOYLPHOSPHATIDYLCHOLINE; LIPOSOME; MORPHINE DERIVATIVE; OPIATE;

ALLODYNIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; AREA UNDER THE CURVE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG ACTIVITY; ENCAPSULATION; MOTOR PERFORMANCE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SUSTAINED RELEASE PREPARATION;

EID: 0033862511     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/00000539-200008000-00036     Document Type: Article

References (24)

1. Analgesia mediated by a direct spinal action of narcotics
2. Prolongation of the pharmacologic effect of intrathecal meperidine by the use of a lipid solution of it
3. The utility of 2-hydroxypropyl-β-cyclodextrin as a vehicle for the intracerebral and intrathecal administration of drugs
4. Liposome encapsulation prolongs alfentanil spinal analgesia and alters systemic redistribution in the rat
5. Antinociception and side effects of liposome-encapsulated alfentanil after spinal delivery in rats
6. Intrathecal administration of liposomal morphine in a mouse model
7. 2 injury
8. Antinociception and side effects of L- and D-dipalmitoylphosphatidyl choline liposome-encapsulated alfentanil after spinal delivery in rats
9. Chronic catheterization of the spinal subarachnoid space
10. Characterization of variables defining hindpaw withdrawal latency evoked by radiant thermal stimuli
11. Sustained-release morphine for epidural analgesia in rats
12. Studies of the pharmacology and pathology of intrathecally administered 4-anilinopiperidine analogues and morphine in the rat and cat
13. Toxicity of bupivacaine encapsulated into liposomes and injected intravenously: Comparison with plain solutions
14. Prolonged analgesia and decreased toxicity with liposomal morphine in a mouse model
15. Direct cerebrospinal fluid delivery of an antiretroviral agent using multivesicular liposomes
16. Pharmacokinetics and efficacy of epidurally delivered sustained-release encapsulated morphine in dogs
17. Spinal anesthesia: Significant prolongation of the pharmacologic effect of tetracaine with lipid solution of the agent
18. Prolongation of canine epidural anesthesia by liposome encapsulation of lidocaine
19. Touch-evoked agitation produced by spinally administered phospholipid emulsion and liposomes in rats
20. Liposomes in drug delivery: Clinical, diagnostic and ophthalmic potential
21. Liposome toxicity in the mouse central nervous system
22. Distribution of morphine and meperidine after intrathecal administration in rat and mouse
23. Distribution in cerebrospinal fluid, blood and lymph of epidurally injected morphine and insulin in dogs