Alkylator resistance in human B lymphoid cell lines: (1) melphalan accumulation, cytotoxicity, Interstrand-DNA-Crosslinks, cell cycle analysis, and glutathione content in the melphalan-sensitive B-Lymphocytic cell line (WIL2) and in the melphalan-resistant B-CLL cell line (WSU-CLL)

Anticancer Research

Volumn 20, Issue 4, 2000, Pages 2561-2568

  Pu, Qingqiu ^a   Bianchi, Pepita ^b   Bezwoda, Werner Roberts ^b  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF THE WITWATERSRAND MEDICAL SCHOOL   (South Africa)

Author keywords

Alkylator resistance; Cell cycle; Interstrand DNA crosslinks; Melphalan accumulation

Indexed keywords

ALKYLATING AGENT; GLUTATHIONE TRANSFERASE; MELPHALAN;

AMINO ACID TRANSPORT; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; CROSS LINKING; DNA REPAIR; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG RESISTANCE; DRUG TRANSPORT; DRUG UPTAKE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, ALKYLATING; B-LYMPHOCYTES; BIOLOGICAL TRANSPORT; CELL CYCLE; CELL LINE; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; LEUKEMIA, B-CELL, CHRONIC; MELPHALAN;

EID: 0033862320     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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