Hypoglycaemic activity of an aqueous extract from Ficus carica (fig tree) leaves in streptozotocin diabetic rats

Pharmaceutical Biology

Volumn 38, Issue 3, 2000, Pages 181-186

  Perez C ^a   Dominguez E ^a   Canal, J R ^a   Campillo, J E ^a   Torres, M D ^a  

^a UNIVERSITY OF EXTREMADURA   (Spain)

Author keywords

Ficus carica; Hypoglycaemic plant; Rat hindquarter perfusion; Streptozotocin diabetic rats

Indexed keywords

ANTIDIABETIC AGENT; FICUS CARICA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; INSULIN BLOOD LEVEL; INSULIN RELEASE; NONHUMAN; RAT; STREPTOZOCIN DIABETES;

ANIMALIA; CARICA; FICUS (ANGIOSPERM); FICUS CARICA;

EID: 0033862250     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1076/1388-0209(200007)3831-SFT181     Document Type: Article

References (29)

1. Adamson I, Okafor C (1990): A supplement of dikanut (Irvingia gabonensis) improves treatment of type II diabetics. West African J Med 9: 108-115.
2. Anderson JW, Akanji AO (1991): Dietary fiber - an overview. Diabetes Care 14: 1126-1131.
3. Bailey CJ, Day C (1989): Traditional plant medicines as treatments for diabetes. Diabetes Care 8: 553-564.
4. Dall'aglio E, Chang H, Hollenbeck CB, Mondon CE, Sims C, Reaven GM (1985): In vivo and in vitro resistance to maximal insulin-stimulated glucose disposal in insulin deficiency. Am J Physiol 249: E312-E316.
5. Day C (1995): Hypoglycaemic plant compounds. Practical Diabetes International 12: 269-271.
6. De Fronzo RA, Jacot E, Jequier E (1981): The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterisation. Diabetes 30: 1000-1007.
7. Fleurentin J, Pelt JM (1990): Las plantas medicinales. Mundo Científico 105: 927-934.
8. Guide to the Care and Use of Experimental Animals. Edited by The Canadian Council on Animal Care Vol. 1 (2nd ed., 1993) and Vol. 2 (1984).
9. Hikino H, Konno C, Miriu Y (1985): Isolation and hypoglycemic activity of ganoderans A and ganoderans B, glycans of "Ganoderma lucidum" fruit bodies. Planta Med 51: 339-340.
10. Ivorra MD, Paya M, Villar A (1989): A review of natural products and plants as potential antidiabetic drugs. J Ethnopharmacol 27: 243-275.
11. James D, Jenkins AB, Kraegen EW (1985): Heterogeneity of insulin action in individual muscles in vivo:euglycemic clamp studies in rats. Am J Physiol 248: E567-E574.
12. Kako M, Miura T, Usami M, Kato A, Kadowaki S (1995): Hypoglycemic effect of the rhizomes of ophiopogonis tuber in normal and diabetic mice. Biol Pharm Bull 18: 875-787.
13. Manchala R, Morse EL, Adibi SA (1990): Mechanism of clearance of dipeptides by perfused hindquarters: sarcolemmal hydrolysis of peptides. Am J Physiol 259: E463-E469.
14. Mandago MA, Boemu L, Bongomola M (1990): Plantes antidiabetiques de Kinshasa (Zaire). Mitt Inst Allg Bot Hamburg 23: 1021-1031.
15. Manfred L (1992): 7000 Recetas Botánicas a Base de 1300 Plantas Americanas. Edited by Kier S.A., Buenos Aires, Argentina, pp. 321-322.
16. Miura T, Kato A (1995): The difference in hypoglycemic action between Polygonati rhizoma and Polygonati officinalis rhizoma. Biol Pharm Bull 18: 1605-1606.
17. Natali A, Buzzigoli G, Ferranini E (1990): Effects of insulin on hemodynamics and metabolism in human forearm. Diabetes 39: 490-500.
18. Noor H, Hammonds P, Sutton R, Ashcroft SJH (1989): The hypoglycaemic and insulinotropic activity of Tinospora crispa: Studies with human and rat islets and HIT-T15 B cells. Diabetologia 32: 354-359.
19. Oshima Y, Sato K, Hikino H (1987): Isolation and hypoglycemic activity of quinquefolans A, B, and C, glycans of Panax quinquefolium roots. J Nat Prod 50: 188-190.
20. Penicaud L, Kande J, Girard JR (1985): Insulin action during fasting and refeeding in rat determined by euglycemic clamp. Am J Physiol 249: E514-E518.
21. Pérez C, Domínguez E, Ramiro JM, Romero A, Campillo JE, Torres MD (1996): A study on the glycaemic balance in streptozotocin-diabetic rats treated with an aqueous extract of Ficus carica (fig tree) leaves. Phytotherapy Res 10: 82-83.
22. Perl M, Hikino H (1989): Effects of some hypoglycemic glycans on glucose uptake and glucose metabolism by inverted intestinal fragments. Phytotherapy Res 5: 207-208.
23. Romans RG, Scott DA, Flisher AM (1940): Preparation of crystalline insulin. Ind Eng Chem 32: 908-912.
24. Ruderman NB, Houghton CRS Hems R (1971): Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism. Biochem J 124: 639-651.
25. Saltiel AR, Fox JA, Sherline P (1986): Insulin stimulated hydrolysis of a novel glycolipid generates modulators of cAMP phosphodiesterase. Science 233: 967-972.
26. Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR (1990): Traditional plant treatments for diabetes: Studies in normal and streptozotocin diabetic mice. Diabetologia 33: 462-464.
27. Thomson AR (1981): Las Plantas Medicinales. Edited by Blume S.A. Barcelona, Spain.
28. Watt J, Wood C (1988): Talking Health: Conventional and Complementary Approaches. Edited by London R Soc Med.
29. WHO Expert Committee (1980): Diabetes Mellitus. (Tech. Rep. Ser. 646). 2nd rep. Geneva, World Health Organization.