Effect of scoring design on the uniformity of extended release matrix tablet halves

Pharmazeutische Industrie

Volumn 62, Issue 7, 2000, Pages 547-550

  Duman, E ^a   Yuksel, N ^a   Olin, B ^a   Sakr, A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Extended release; Half tablets; Matrix tablets; Scoring design; Uniformity

Indexed keywords

ANXIOLYTIC AGENT; API 030611;

ARTICLE; DRUG DETERMINATION; DRUG FORMULATION; DRUG MANUFACTURE; SCORING SYSTEM; SUSTAINED RELEASE PREPARATION; TABLET;

EID: 0033862062     PISSN: 0031711X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Compressed tablets by direct compression
2. Drug release evaluation of diltiazem CR preparations
3. Analysis of in vitro dissolution of whole vs. half controlled-release Theophylline tablets
4. Dissolution and bioavailability studies of whole and halved sustained-release Theophylline tablets
5. Broken tablets: Does sum of the parts equal the whole?
6. Effect of dissolution from halving methylphenidate extended-release tablets
7. A review of methods used to compare dissolution profile data
8. In-vitro dissolution profile comparison: Statistics and analysis. Model dependent approach
9. On the assessment of similarity of drug dissolution profiles - A simulation study
10. Methods to compare dissolution profiles and a rationale for wide dissolution specifications for metoprolol tartrate tablets
11. Mathematical compression of dissolution profile
12. In vitro dissolution profile comparison - Statistics and similarity factor