Peptide display on bacterial flagella: Principles and applications

International Journal of Medical Microbiology

Volumn 290, Issue 3, 2000, Pages 223-230

  Westerlund Wikström, Benita ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Adhesive; Display; Flagellum; Peptides; Random; Vaccines

Indexed keywords

ADHESIN; BACTERIUM ADHERENCE; CONFORMATIONAL TRANSITION; EPITOPE MAPPING; ESCHERICHIA COLI; FLAGELLIN; FLAGELLUM; HYBRID PROTEIN; PEPTIDE LIBRARY; PEPTIDE SYNTHESIS; PHAGE DISPLAY; THIOREDOXIN;

EID: 0033861792     PISSN: 14384221     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1438-4221(00)80119-8     Document Type: Review

References (41)

1. Bourdet-Sicard, R., Rüdiger, M., Jockusch, B. M., Gounon, P., Sansonetti, P. J., Tran Van Nhieu, G.: Binding of the Shigella protein IpaA to vinculin induces F-actin depolymerization. EMBO J. 18, 5853-5862 (1999).
2. Cattozzo, E. M., Stocker, B. A., Radaelli, A., De Giuli Morghen, C., Tognon, M.: Expression and immunogenicity of V3 loop epitopes of HIV-1, isolates SC and WMJ2, inserted in Salmonella flagellin. J. Biotechnol. 28, 191-203 (1997).
3. Choudhury, D., Thompson, A., Stojanoff, V., Langermann, S., Pinkner, J., Hultgren, S. J., Knight, S. D.: X-ray structure of the FimC-FimHchaperone-adhesin complex from uropathogenic Escherichia coli. Science 285, 1061-1065 (1999).
4. Dilts, D. A., Riesenfield-Orn, I., Fulginiti, J. P., Ekwall, E., Granert, C., Nonenmacher, J., Brey, R. N., Cryz., S. J., Karlsson, K., Bergman, K., Thompson, T., Hu, B., Bruckner, A. H., Lindberg, A. A.: Phase I clinical trials of aroA aroD and aroA aroD htrA attenuated S. typhi vaccines; effects of formulation on safety and immunogenicity. Vaccine 18, 1473-1484 (2000).
5. Georgiou, G., Stathopoulos, C., Daugherty, P. S., Nayak, A. R., Iverson, B. L., Curtiss III, R.: Display of heterologous proteins on the surface of microorganisms: From the screening of combinatorial libraries to live recombinant vaccines. Nature Biotechnol. 15, 29-33 (1997).
6. Hamburger, Z. A., Brown, M. S., Isberg, R. R., Bjorkman, P.: Crystal structure of invasin: A bacterial integrin-binding protein. Science 286, 291-295 (1999).
7. 1 encodes a dominant surface epitope and a stabilizing factor for functional flagella. J. Bacteriol. 176, 2406-2414 (1994).
8. Ikeda, T., Oosawa, K., Hotani, H.: Self-assembly of the filament capping protein, FliD, of bacterial flagella into an annular structure. J. Mol. Biol. 259, 679-686 (1996).
9. Källenius, G., Winberg, J.: Bacterial adherence to periurethral cells in girls prone to urinary tract infections. Lancet ii, 540-543 (1978).
10. Karlsson, K.-A.: Animal glycosphingolipids as membrane attachment sites for bacteria. Annu. Rev. Biochem. 58, 309-350 (1989).
11. Katti, S. K., LeMaster, D. M., Eklund, H.: Crystal structure of thioredoxin from E. coli at 1.68 angstroms resolution. J. Mol. Biol. 212, 167-184 (1990).
12. Kelly, G., Prasannan, S., Daniell, S., Fleming, K., Frankel, G., Dougan, G., Connerton, I., Matthews, S.: Structure of the cell-adhesion fragment of intimin from enteropathogenic Escherichia coli. Nature Struct. Biol. 6, 313-318 (1999).
13. Korhonen, T. K., Virkola, R., Westerlund, B., Holthöfer, H., Parkkinen, J.: Tissue tropism of Escherichia coli adhesins in human extraintestinal infections. Curr. Top. Microbiol. Immunol. 151, 115-127 (1990).
14. Kuwajima, G.: Flagellin domain that affects H antigenicity of Escherichia coli K-12. J. Bacteriol. 170, 485-488 (1988a).
15. Kuwajima, G.: Construction of a minimum-size functional flagellin of Escherichia coli. J. Bacteriol. 170, 3305-3309 (1988b).
16. Kuwajima, G., Asaka, J.-I., Fujiwara, T., Fujiwara, T., Nakano, K., Kondoh, E.: Presentation of an antigenic determinant from hen egg-white lysozyme on the flagellar filament of Escherichia coli. Biotechnology 6, 1080-1083 (1988).
17. LaVallie, E. R., Diblasio, E. A., Kovacic, C., Grant, K. L., Schendel, P. F., McCoy, J. M.: A thioredoxin gene fusion expression system that circumvents inclusion body formation in the Escherichia coli cytoplasm. Biotechnology 11, 1187-1193 (1993).
18. Levi, R., Arnon, R.: Synthetic recombinant influenza vaccine induces efficient long-term immunity and cross-strain protection. Vaccine 14, 85-92 (1996).
19. Lu, Z., Murray, K. S., Van Cleave, V., LaVallie, E. R., Stahl, M. L., McCoy, M.: Expression of thioredoxin random peptide libraries on the Escherichia coli cell surface as functional fusions to flagellin: a system designed for exploring protein-protein interactions. Biotechnology 13, 366-372 (1995).
20. Luna, M. G., Martins, M. M., Newton, S. M., Costa, S. O., Almeida, D. F., Ferreira, L. C.: Cloning and expression of colonization factor antigen I (CFA/I) epitopes of enterotoxigenic Escherichia coli (ETEC) in Salmonella flagellin. Res. Microbiol. 148, 217-218 (1997).
21. nd edition (F. C. Neidhardt, J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, H. E. Umbarger, eds.), pp. 123-145. American Society for Microbiology, Washington D. C. 1995.
22. McEwen, J., Levi, R., Horwitz, R. J., Arnon, R.: Synthetic recombinant vaccine expressing influenza haemagglutinin epitope in Salmonella flagellin leads to partial protection in mice. Vaccine 10, 405-411 (1992).
23. Namba, K., Yamashita, I., Vonderviszt, F.: Structure of the core and central channel of bacterial flagella. Nature 342, 648-654 (1989).
24. Newton, S. M. C., Jacob, C. O., Stocker, B. A.: Immune response to cholera toxin epitope inserted in Salmonella flagellin. Science 244, 70-72 (1989).
25. Newton, S. M. C., Kotob, M., Poirier, T. P., Stocker, B. A. D., Beachey, E. H.: Expression and immunogenicity of a streptococcal M protein epitope inserted in Salmonella flagellin. Infect. Immun. 59, 2158-2165 (1991).
26. Newton, S. M. C., Joys, T. M., Anderson, S. A., Kennedy, R. C., Hovi, M. E, Stocker, B. A.: Expression and immunogenicity of an 18-residue epitope of HIV1 gp41 inserted in the flagellar protein of a Salmonella live vaccine. Res. Microbiol. 146, 203-216 (1995).
27. Pickett, T. E., Pasetti, M. F., Galen, J. E., Sztein, M. B., Levine, M. M.: In vivo characterization of the murine intranasal model for assessing the immunogenicity of attenuated Salmonella enterica serovar Typhi strains as live mucosal vaccines and as live vectors. Infect. Immun. 68, 205-213 (2000).
28. Rich, R. L., Demeler, B., Ashby, K., Deivanayagam, C. C. S., Petrich, J. W., Patti, J. M., Narayana, S. V. L., Höök, M.: Domain structure of the Staphylococcus aureus collagen adhesin. Biochemistry 37, 15423-15433 (1998).
29. Rodi, D. J., Makowski, L.: Phage-display technology - finding a needle in a vast molecular haystack. Curr. Opin. Biotechnol. 10, 87-93 (1999).
30. Roggenkamp, A., Neuberger, H.-R., Flugel, A., Schmoll, T., Heesemann, J.: Substitution of two histidine residues in YadA protein of Yersinia enterocolitica abrogates collagen binding, cell adherence and mouse virulence. Mol. Microbiol. 16, 1207-1219 (1995).
31. Signäs, C., Raucci, G., Jönsson, K., Lindgren, P.-E., Ananantharamaiah, G. M., Höök, M., Lindberg, M.: Nucleotide sequence of the gene for a fibronectin-binding protein from Staphylococcus aureus: use of this peptide sequence in the synthesis of biologically active peptides. Proc. Natl. Acad. Sci USA 86, 699-703 (1989).
32. Ståhl, S., Uhlén, M.: Bacterial surface display: trends and progress. Trends Biotechnol. 15, 185-192 (1997).
33. Symersky, J., Patti, J. M., Carson, M., House-Pompeo, K., Teale, M., Moore, D., Jin, L., Schneider, A., DeLucas, L. J., Höök, M., Narayana, S. V. L.: Structure of the collagen-binding domain from a Staphylococcus aureus adhesin. Nature Struct. Biol. 4, 833-838 (1997).
34. Tamm, A., Tarkkanen, A.-M., Korhonen, T. K., Kuusela, P., Toivanen, P., Skurnik, M.: Hydrophobic domains affect the collagen-binding specificity and surface polymerization as well as the virulence potential of the YadA protein of Yersinia enterocolitica. Mol. Microbiol. 10, 995-1011 (1993).
35. Thankavel, K., Shah, A. H., Cohen, M. S., Ikeda, T., Lorenz, R. G., Curtiss III, R., Abraham, S. N.: Molecular basis for the enterocyte tropism exhibited by Salmonella typhimurium type 1 fimbriae. J. Biol. Chem. 274, 5797-5809 (1999).
36. Vanegas, R. A., Street, N. E., Joys, T. M.: In a vaccine model, selected substitution of a highly stimulatory T cell epitope of hen's egg lysozyme into a Salmonella flagellin does not result in a homologous, specific, cellular immune response and may alter the way in which the total antigen is processed. Vaccine 15, 321-324 (1997).
37. Verma, N. K., Ziegler, H. K., Wilson, M., Khan, M., Safley, S., Stocker, B. A., Schoolnik, G. K.: Delivery of class I and class II MHC-restricted T-cell epitopes of listeriolysin of Listeria monocytogenes by attenuated Salmonella. Vaccine 13, 142-150 (1995).
38. Westerlund-Wikström, B., Tanskanen, J., Virkola, R., Hacker, J., Lindberg, M., Skurnik, M., Korhonen, T. K.: Functional expression of adhesive peptides as fusions to Escherichia coli flagellin. Protein Eng. 10, 1319-1326 (1997).
39. Whittle, B. L., Lee, E., Weir, R. C., Verma, N. K.: Immune response to a Murray valley encephalitis virus epitope expressed in the flagellin of an attenuated strain of Salmonella. J. Med. Microbiol. 46, 129-138 (1997).
40. Wilson, D. R., Beveridge, T. J.: Bacterial flagellar filaments and their component flagellins. Can. J. Microbiol. 39, 452-472 (1993).
41. Wu, J. Y., Newton, S., Judd, S., Stocker, B., Robinson, W. S. (1989) Expression of immunogenic epitopes of hepatitis B surface antigen with hybrid flagellin proteins by a vaccine strain of Salmonella. Proc. Natl. Acad. Sci. USA 86, 4726-4730.