High-level amikacin resistance in Pseudomonas aeruginosa associated with a 3'-phosphotransferase with high affinity for amikacin

International Journal of Antimicrobial Agents

Volumn 15, Issue 4, 2000, Pages 257-263

  Torres, Carmen ^a   Perlin, Michael H ^b   Baquero, Fernando ^c   Lerner, Deborah L ^d   Lerner, Stephen A ^e  

^a UNIVERSITY OF LA RIOJA   (Spain)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

^d WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WAYNE STATE UNIVERSITY   (United States)

Author keywords

Amikacin resistance; APH(3') VI; Kinetics analyses; Pseudomonas aeruginosa; Purification

Indexed keywords

2' N ETHYLNETILMICIN; 6' N ETHYLNETILMICIN; AMIKACIN; BUTIROSIN; GENTAMICIN C; KANAMYCIN; LIVIDOMYCIN; NETILMICIN; PAROMOMYCIN; PHOSPHOTRANSFERASE; RIBOSTAMYCIN; STREPTOMYCIN; TOBRAMYCIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SOUTHERN BLOTTING;

AMIKACIN; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BLOTTING, SOUTHERN; DNA PRIMERS; DRUG RESISTANCE, MICROBIAL; KINETICS; MICROBIAL SENSITIVITY TESTS; PHOSPHOTRANSFERASES; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; SUBSTRATE SPECIFICITY;

EID: 0033861098     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-8579(00)00174-6     Document Type: Article

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