The tensegrity model applied to the lens: A hypothesis for the presence of the fiber cell ball and sockets

Medical Hypotheses

Volumn 55, Issue 1, 2000, Pages 36-39

  Yamada, T ^a   Richiert, D ^a   Tumminia, S J ^a   Russell, P ^a  

^a NATIONAL EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYSTALLIN;

ANIMAL CELL; CELL DIFFERENTIATION; CELL MATURATION; CELL NUCLEUS; CELL ORGANELLE; CONTROLLED STUDY; CYTOSKELETON; EPITHELIUM CELL; FIBER; IN SITU HYBRIDIZATION; LENS EPITHELIUM; LENS FIBER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW; TENSION;

ANIMALIA;

EID: 0033859047     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1054/mehy.1999.0994     Document Type: Article

References (20)

1. Ingber D. E., Jamieson J. D. Cells as tensegrity structures: architectural regulation of histodifferentiation by physical forces transduced over basement membrane. Andersson L. C., Gahmberg C. G., Elkblom P. Gene Expression During Normal and Malignant Differentiation. 1985;13-32 Academic Press, Orlando, FI.
2. Ingber D. E. Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton. J Cell Sci. 104:1993;613-627.
3. Ingber D. E., Dike L., Hansen L., Karp S., Liley H., Maniotis A., McNamee H., Mooney D., Plopper G., Sims J. Cellular tensegrity: exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis. Int Rev Cytol. 150:1994;173-224.
4. Ingber D. E., Prusty D., Sun Z., Betensky H., Wang N. Cell shape, cytoskeletal mechanics and cell cycle control in angiogenesis. J Biomech. 28:1995;1471-1484.
5. Ingber D. E. Tensegrity: the architectural basis of cellular mechano-transduction. Annu Rev Physiol. 59:1997;575-599.
6. Ingber D. E. Architecture of life. Sci Am. 278:1998;48-57.
7. Ingber D. E. Integrins as mechanochemical transducers. Curr Opin Cell Biol. 3:1991;841-848.
8. Sims J. R., Karp S., Ingber D. E. Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape. J Cell Sci. 102:1992;1215-1222.
9. Maniotis A. J., Chen C. S., Ingber D. E. Demonstration of mechanical connections between integrins, cytoskeletal filaments and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci USA. 94:1997;849-854.
10. Tumminia S. J., Mitton K. P., Arora J., Zelenka P., Epstein D. L., Russell P. Mechanical stretch alters the actin cytoskeletal network and signal transduction in human trabecular meshwork cells. Invest Ophthal Vis Sci. 39:1998;1361-1373.
11. Prescott A. R., Sandilands A., Hutcheson A. M., Carter J. M., Quinlan R. A. The intermediate filament cytoskeleton of the lens: an ever changing network through development and differentiation. Ophthalmic Res. 28:1996;58-61.
12. Piatigorsky J., Rothschild S. S., Milstone L. M. Differentiation of lens fibers in explanted embryonic chick lens epithelia. Develop Biol. 34:1973;334-345.
13. Bekhor I. MP26 messenger RNA sequences in normal and cataractous lens. Invest Ophthalmol Vis Sci. 29:1988;802-813.
14. Bekhor I., Shi S., Unakar N. J. Aldose reductase mRNA is an epithelial cell-specific gene transcript in both normal and cataractous rat lens. Invest Ophthalmol Vis Sci. 31:1990;1876-1885.
15. Block S. M. Kinesin: what gives? Cell. 93:1998;5-8.
16. Lohman T. M., Thorn K., Vale R. D. Staying on track: common features of DNA helicases and microtubule motors. Cell. 93:1998;9-12.
17. Kuwabara T. The maturation of the lens cell: a morphologic study. Exp Eye Res. 20:1975;427-443.
18. Bradley R. H., Ireland M., Maisel H. The cytoskeleton of chick lens cells. Exp Eye Res. 28:1979;441-453.
19. Vrensen G. F. J. M., Duindam H. J. Maturation of fiber membranes in the human eye lens. Ophthalmic Res. 27:1995;78-85.
20. Zigman S., Paxhia T., Marinetti G., Girsch S. Lipids of human lens fiber cell membranes. Curr Eye Res. 3:1984;887-896.